Results 41 to 50 of about 5,690 (176)
Arthritis &Rheumatology, EarlyView.Objective Axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) are overlapping yet distinct conditions within the SpA spectrum. As divergent immunophenotypes may influence disease course and therapeutic response, we compared immune cell subsets, cytokine profiles, and inflammatory mediators.
Natalie Frede +11 more
wiley +1 more source
Biomarkers of lung congestion and injury in acute heart failure
ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi +9 more
wiley +1 more source
The Significance of Elevated sST2 in Children with Kawasaki Disease
ChildrenObjectives: To investigate the level and clinical significance of soluble growth stimulation expressed gene 2 protein (sST2) in children with Kawasaki Disease (KD). Methods: A retrospective analysis was performed on 287 cases of KD in pediatric cardiology Department of Shengjing Hospital Affiliated to China Medical University from November 2021 to ...
Zhaohua Yang +4 more
openaire +3 more sources
慢性阻塞性肺疾病患者血清IL-33、sST2、CRP水平与病情严重程度的相关性研究
Zhongguo shiyan zhenduanxue, 2021 目的探讨慢性阻塞性肺疾病(COPD)患者血清白介素33(IL-33)、可溶性生长刺激表达基因2蛋白(sST2)、C反应蛋白(CRP)与病情严重程度的相关性。方法收集南通市第二人民医院呼吸内科2019年1月-2020年10月期间COPD患者146例,检测并比较患者血清IL-33、sST2和CRP的变化,测定并计算COPD患者的FEV1占预计值百分比(FEV1%预计值),分析CRP、sST2、sST2/IL-33比值与FEV1%预计值的相关性。结果 COPD急性加重期(AECOPD)患者血清CRP ...
张曙晴 +4 more
doaj
Predictive value of soluble ST2 in adolescent and adult patients with complex congenital heart disease. [PDF]
PLoS ONE, 2018 BACKGROUND:Soluble suppression of tumorogenicity 2 (sST2) has been shown to be of prognostic value in patients with chronic and acute left heart failure.
Mohammed Laqqan +3 more
doaj +1 more source
Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy
ESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo +7 more
wiley +1 more source
iMeta, EarlyView.The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Cellular Noise Suppression by the Regulator of G Protein Signaling Sst2 [PDF]
Molecular Cell, 2014 G proteins and their associated receptors process information from a variety of environmental stimuli to induce appropriate cellular responses. Generally speaking, each cell in a population responds within defined limits despite large variation in the expression of protein signaling components.
Dixit, Gauri +4 more
openaire +2 more sources
EJNMMI Research, 2020 Background Somatostatin receptor (SST) targeting, specifically of the subtype 2 (SST2), with radiolabeled somatostatin analogs, is established for imaging and treatment of neuroendocrine tumors.
Rosalba Mansi +5 more
doaj +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT One of the most serious complications associated with the use of the chemotherapeutic agent doxorubicin (DOX) is cardiomyopathy. Although cardioprotective drugs such as angiotensin receptor‐neprilysin inhibitors (ARNI) are used to prevent cardiomyopathy in DOX patients, no studies have reported the relationship between ARNI and endoplasmic ...
Mert Unvan +3 more
wiley +1 more source