Results 41 to 50 of about 8,618 (210)
Cardiovascular Diabetology, 2021 Background Soluble suppression of tumorigenesis-2 (sST2) is implicated in myocardial overload and has long been recognized as an inflammatory marker related to heart failure and acute coronary syndrome, but data on the prognostic value of sST2 in ...
Man Li +6 more
semanticscholar +1 more source
PLoS ONE, 2020 BackgroundProinflammatory interleukin-33 (IL-33) binds to its receptor ST2L and is involved in inflammation and the malignant behavior of cancer cells.
Keizo Takenaga +3 more
doaj +1 more source
medRxiv, 2021 Importance: Although several biomarkers have shown correlation to prognosis in COVID-19 patients, their clinical value is limited because of lack of specificity, suboptimal sensibility, or poor dynamic behavior.
M. Sánchez-Marteles +8 more
semanticscholar +1 more source
Effect of β-Blocker Therapy on the Level of Soluble ST2 Protein in Pediatric Dilated Cardiomyopathy
Medicina, 2022 Background and Objectives: A prognosis for kids with pediatric dilated cardiomyopathy (PDCM) is urgently needed to identify high-risk patients. This study aimed to determine the association of levels and soluble suppression of tumorigenicity 2 (sST2) and
Meng Jiao +7 more
doaj +1 more source
The Tyrosine Phosphatase SHP-1 Associates with the sst2 Somatostatin Receptor and Is an Essential Component of sst2-mediated Inhibitory Growth Signaling [PDF]
Journal of Biological Chemistry, 1997 Activation of the somatostatin receptor sst2, a member of the Gi protein-coupled receptor family, results in the stimulation of a protein-tyrosine phosphatase activity involved in the sst2-mediated growth inhibitory signal. Here, we report that SHP-1, a cytoplasmic protein-tyrosine phosphatase containing two Src homology 2 domains constitutively ...
F, Lopez +8 more
openaire +2 more sources
The miRNA199a/SIRT1/P300/Yy1/sST2 signaling axis regulates adverse cardiac remodeling following MI
Scientific Reports, 2021 Left ventricular remodeling following myocardial infarction (MI) is related to adverse outcome. It has been shown that an up-regulation of plasma soluble ST2 (sST2) levels are associated with lower pre-discharge left ventricular (LV) ejection fraction ...
M. Asensio-Lopez +5 more
semanticscholar +1 more source
Predictive values of sST2 and IL-33 for heart failure in patients with acute myocardial infarction
Experimental biology and medicine, 2021 Timely prediction of the risk of heart failure in acute myocardial infarction patients is critical for better prognosis. This article aims to evaluate the predictive value of serum soluble growth stimulation expressed gene 2 (sST2) and interleukin-33 in ...
Jingxian Xing, Junyan Liu, T. Geng
semanticscholar +1 more source
IL-33 and its decoy sST2 in patients with Alzheimer’s disease and mild cognitive impairment
Journal of Neuroinflammation, 2020 Background Interleukin-33 is a cytokine endowed with pro- and anti-inflammatory properties that plays a still poorly defined role in the pathogenesis of a number of central nervous system (CNS) conditions including Alzheimer’s disease (AD).
M. Saresella +7 more
semanticscholar +1 more source
Frontiers in Cardiovascular Medicine, 2022 BackgroundBoth β1 adrenergic receptor autoantibody (β1-AA) and soluble suppression of tumorigenicity-2 (sST2) take a role in the pathological remodeling of heart failure.
Yanxiang Sun +6 more
doaj +1 more source
Science Advances, 2020 We uncovered sST2 as an obesity-induced adipokine that exacerbates adipose Treg/ILC2 depletion and promotes insulin resistance. Depletion of fat-resident regulatory T cells (Tregs) and group 2 innate lymphoid cells (ILC2s) has been causally linked to ...
Xu-Yun Zhao +7 more
semanticscholar +1 more source