Results 71 to 80 of about 12,750 (218)

IL-33 ameliorates Alzheimer’s disease-like pathology and cognitive decline [PDF]

, 2016
Alzheimer’s disease (AD) is a devastating condition with no known effective treatment. AD is characterized by memory loss as well as impaired locomotor ability, reasoning, and judgment.
Chan, Ivy C. W., Cheung, Tom H., Fu, Amy K. Y., Fu, Wing-Yu, Hung, Kwok-Wang, Ip, Nancy Y., Liew, Foo Y., Mak, Deejay S. Y., Yuen, Michael Y. F., Zhang, Baorong, Zhou, Xiaopu   +10 more
core   +1 more source

The modulating effect of circulating carbohydrate antigen 125 on ST2 and long-term recurrent morbidity burden

Scientific Reports
Soluble ST2 (sST2) is released in response to vascular congestion, inflammation, and pro-fibrotic stimuli. In heart failure (HF), elevated levels of sST2 are associated with a higher risk of adverse clinical outcomes.
Elena Revuelta-López, Rafael de la Espriella, Gema Miñana, Enrique Santas, Sandra Villar, Juan Sanchis, Antoni Bayés-Genís, Julio Núñez   +7 more
doaj   +1 more source

ST2 and IL-33 in pregnancy and pre-eclampsia. [PDF]

PLoS ONE, 2011
Normal pregnancy is associated with a mild systemic inflammatory response and an immune bias towards type 2 cytokine production, whereas pre-eclampsia is characterized by a more intense inflammatory response, associated with endothelial dysfunction and a
Ingrid Granne, Jennifer H Southcombe, James V Snider, Dionne S Tannetta, Tim Child, Christopher W G Redman, Ian L Sargent   +6 more
doaj   +1 more source

Monitoring of biomarkers in heart failure. [PDF]

, 2019
The role of biomarkers is increasingly recognized in heart failure (HF) management, for diagnosis, prognostication, and screening of high-risk patients.
Agewall, Agewall, Agewall, Agostoni, Andrew J S Coats, Ather, Bayes-Genis, Bhambhani, Binas, Broch, Demissei, Felker, Giuseppe M C Rosano, Graham, Greene, Hallén, Harjola, Hoedemaker, Ilaria Spoletini, Januzzi, Januzzi, Ky, McCarthy, Michele Senni, Mueller, Nadar, O'Meara, Pareek, Paul, Peacock, Perk, Ponikowski, Rastogi, Salmonson, Sarhene, Sato, Schneider, Shah, Squire, Stenemo, Tamargo, Troughton, Welsh, Xue   +43 more
core   +1 more source

Soluble ST2 and risk of cognitive impairment after acute ischemic stroke: a prospective observational study

BMC Geriatrics, 2021
Background Soluble suppression of tumorigenesis-2 (sST2) was reported to be associated with cognitive performance and risk of incident stroke. However, the impact of sST2 on cognitive function after ischemic stroke is unclear.
Yinwei Zhu, Chongquan Fang, Qi Zhang, Yaling Lu, Rui Zhang, Aili Wang, Xiaoqing Bu, Jintao Zhang, Zhong Ju, Yonghong Zhang, Tan Xu, Chongke Zhong   +11 more
doaj   +1 more source

Soluble suppression of tumorigenicity 2 associated with atrial fibrillation detected after stroke: A retrospective study

Heliyon, 2023
Background: The soluble suppression of tumorigenicity 2 (sST2) is closely associated with stroke and atrial fibrillation (AF). However, no studies on sST2 and AF detected after stroke (AFDAS) have been reported.
Wenquan Hou, Yong Li, Jing Wang, Menghua Xu, Siwen Wu, Wen Li, Suhua Qi   +6 more
doaj   +1 more source

Status of soluble ST2 levels in serum of HTLV-1 infected individuals [PDF]

, 2015
ST2 is a member of IL-1 receptor family expressed on Th2 cells and regulates Th2 responces. The gene of ST2 encodes soluble ST2 (sST2) and the transmembrane ST2 (ST2L) isoforms through alternative mRNA splicing.
Avval, Farnaz Zahedi, Boostani, Reza, Jarahi, Lida, Nadri, Mohammad, Shomali, Shadi, Youssefi, Masoud   +5 more
core   +1 more source

The Association of Serum IL-33 and sST2 with Breast Cancer [PDF]

Disease Markers, 2015
Breast cancer is one of the most common malignant diseases in women. The main cause of death from breast cancer is its metastases at distant sites in the body. Interleukin-33 (IL-33) is a cytokine of the IL-1 family and found overexpressed in various cancers.
Yang, Zhi-Ping, Ling, Dan-Yan, Xie, Yong-Hong, Wu, Wan-Xin, Li, Jin-Rui, Jiang, Jin, Zheng, Jia-Lian, Fan, Yao-Hua, Zhang, Ye   +8 more
openaire   +2 more sources

Serum Levels of Soluble ST2 and IL-10 Are Associated with Disease Severity in Patients with IgA Nephropathy

Journal of Immunology Research, 2016
Background. The IL-33/ST2 axis is involved in humoral immune responses. Method. The concentrations of sera IL-33 and sST2 in 74 patients and 34 healthy controls (HC) were measured by ELISA. Clinical and laboratory data were examined.
Zhihui Zhang, Haifeng Wang, Li Zhang, Rebecca Crew, Nan Zhang, Xiaolei Liu, Yanfang Jiang   +6 more
doaj   +1 more source

sST2: a new kid on the block for patients with ACHD [PDF]

Heart, 2019
Adults with congenital heart disease (ACHD) are an increasing and ageing population.1 Despite all advances in medical and surgical treatment, patients with ACHD are still afflicted by significant morbidity and mortality.2 Timely identification of those patients that are at risk can be difficult.
openaire   +2 more sources