Results 51 to 60 of about 6,330 (191)

Outbreak of OXA-48 carbapenemase-producing Klebsiella pneumoniae in Greece involving an ST11 clone [PDF]

Journal of Antimicrobial Chemotherapy, 2012
First detected in Enterobacteriaceae isolates in Turkey, the OXA-48 carbapenemase has gradually disseminated in the wider Mediterranean area and Europe. Despite reports from other European regions, until now no such isolates have been detected in Greece.
Voulgari, E., Zarkotou, O., Ranellou, K., Karageorgopoulos, D.E., Vrioni, G., Mamali, V., Themeli-Digalaki, K., Tsakris, A.   +7 more
openaire   +3 more sources

Emergence of tigecycline-resistant Klebsiella pneumoniae ST11 clone in patients without exposure to tigecycline

The Journal of Infection in Developing Countries, 2021
Introduction: Tigecycline is a unique class of semi-synthetic glycylcyclines developed to treat infections caused by multidrug-resistant Klebsiella pneumoniae. In the past decades, eight tigecycline-resistant Acinetobacter baumannii isolates have been identified in Tehran and no Klebsiella pneumoniae has been reported.
Rezvan Goodarzi, Mohammadreza Arabestani, Mohmmad Yousef Alikhani, Fariba Keramat, Babak Asghari   +4 more
openaire   +4 more sources

Emergence of Hypervirulent ST11-K64 Klebsiella pneumoniae Poses a Serious Clinical Threat in Older Patients [PDF]

Frontiers in Public Health, 2022
The carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) poses a severe therapeutic challenge to global public health, and research on CR-hvKP in older patients remain limited. In this study, we aimed to investigate the clinical and molecular characteristics and risk factors of CR-hvKP infections in older patients.
Tian Wei, Chengyun Zou, Jie Qin, Jianmin Tao, Li Yan, Jiangjun Wang, Hong Du, Fang Shen, Yanqin Zhao, Haiying Wang   +9 more
openaire   +3 more sources

Emergence of ST11-K47 and ST11-K64 hypervirulent carbapenem-resistant Klebsiella pneumoniae in bacterial liver abscesses from China: a molecular, biological, and epidemiological study

, 2020
Background: Multidrug-resistant bacteria, especially those with high virulence, are an emerging problem in clinical settings. Methods: We conducted a multicentre epidemiological and comparative genomic analysis on the evolution, virulence and ...
Timothy Kudinha (647162), Xinmiao Jia (4783635), Wenhang Yang (8428944), Yingchun Xu (320157), Qiwen Yang (795448), Menglan Zhou (3444182), Hui Zhang (7197)   +6 more
core   +1 more source

Tracking a hospital outbreak of KPC-producing ST11 Klebsiella pneumoniae with whole genome sequencing [PDF]

Clinical Microbiology and Infection, 2015
An outbreak of carbapenem-resistant Klebsiella pneumoniae strains emerged at a hospital, and was tracked in order to understand the spread of these infectious pathogens. A total of 66 K. pneumoniae strains were collected from sterile samples in 2012. The MICs of 20 antimicrobial agents were determined for all strains.
Jiang, Y., Wei, Z., Wang, Y., Hua, X., Feng, Y., Yu, Y.   +5 more
openaire   +2 more sources

Dynamic Epidemiology and Virulence Characteristics of Carbapenem-Resistant Klebsiella pneumoniae in Wenzhou, China from 2003 to 2016

Infection and Drug Resistance, 2020
Yajie Zhao,1,2 Siqin Zhang,1 Renchi Fang,1 Qing Wu,1 Jiahui Li,1 Yizhi Zhang,1 Andrea Rocker,3 Jianming Cao,2 Trevor Lithgow,3 Tieli Zhou1 1Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People ...
Zhao Y, Zhang S, Fang R, Wu Q, Li J, Zhang Y, Rocker A, Cao J, Lithgow T, Zhou T   +9 more
doaj  

Genetic and Phenotypic Characteristics of Carbapenem-Resistant Klebsiella pneumoniae Isolates from a Tertiary Hospital in Beijing

Infection and Drug Resistance, 2022
Qin Ni,1,2,* Xingwei Yao,3,* Jinhui Li,2,* Jinghan Ma,3,* Kaiying Wang,2 Xiong Liu,2 Peihan Li,2 Lang Yang,2 Peng Li,2 Shenlong Li1,2 1Epidemiology, Zhengzhou University, Zhengzhou, People’s Republic of China; 2Biosafety, Chinese PLA ...
Ni Q, Yao X, Li J, Ma J, Wang K, Liu X, Li P, Yang L, Li P, Li S   +9 more
doaj  

Clonal Dissemination of Clinical Carbapenem-Resistant Klebsiella pneumoniae Isolates Carrying fosA3 and blaKPC–2 Coharboring Plasmids in Shandong, China

Frontiers in Microbiology, 2021
Treatment strategies of infection by carbapenem-resistant Klebsiella pneumoniae (CRKP) are limited. Fosfomycin, a broad-spectrum antibiotic, has attracted renewed interest in combination therapy to fight K. pneumoniae infections.
Yingying Hao, Yingying Hao, Xuguang Zhao, Cui Zhang, Yuanyuan Bai, Zhen Song, Xinglun Lu, Ran Chen, Yaoyao Zhu, Yueling Wang   +9 more
doaj   +1 more source

Uncovering the gut microbiota as a reservoir of ST11 hypervirulent KPC-2-producing Klebsiella pneumoniaeUncovering the gut microbiota as a reservoir of ST11 hypervirulent KPC-2-producing Klebsiella pneumoniae [PDF]

, 2019
Abstract Background: The emergence and spread of ST11 carbapenem-resistant, hypervirulent K. pneumonia (ST11-CR-HvKP) in China generated great concern from the public health community. The identification of ST11-CR-HvKP strain is expected to become a serious public health issue in China, considering the carbapenem resistance and virulence had ...
Beiwen Zheng, Hao Xu, Tao Lv, Lihua Guo, Xiao Yu, Chen Huang, Shuntian Zhang, Yunbo Chen, Huiming Han, Ping Shen, Yonghong Xiao, Lanjuan Li   +11 more
openaire   +1 more source

Molecular epidemiology, risk factors, and outcomes of carbapenem-resistant Klebsiella pneumoniae infection in a tertiary hospital in eastern China: for a retrospective study conducted over 4 years

Frontiers in Microbiology, 2023
ObjectivesCarbapenem-resistant Klebsiella pneumoniae (CRKP) have been extensively disseminated worldwide, resulting in increased mortality. We performed a retrospective analysis of the epidemiology and risk factors for the outcome of CRKP infection in a ...
Jun Cheng, Dongmei Zhao, Xuejiao Ma, Jiabin Li   +3 more
doaj   +1 more source