Results 31 to 40 of about 6,330 (191)

Two outbreak cases involving ST65-KL2 and ST11-KL64 hypervirulent carbapenem-resistant Klebsiella pneumoniae: similarity and diversity analysis

Communications Biology
The rise of the convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniae has been increasingly reported in recent years, however, there are few outbreak cases for these producing NDM carbapenemase. In this study, ST65-KL2 and ST11-
Feilong Zhang, Zhihua Li, Ziyao Li, Xinmeng Liu, Zichen Lei, Xianxia Zhuo, Xinrui Yang, Jiankang Zhao, Yulin Zhang, Binghuai Lu   +9 more
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Virulence attenuation in ST11-K64 Klebsiella pneumoniae explains its divergent clinical manifestation from ST23-K1 [PDF]

Virulence
The clinical threat posed by Klebsiella pneumoniae is dual-faceted, encompassing both hypervirulence and carbapenem resistance. The emergence of hypervirulent carbapenem-resistant K.
Shujing Li, Ying Zhang, Qian Zeng, Lilan Zheng, Jing Yan, Yong Wang, Yun Liu, Lianhua Yu, Yi Li, Meng Li, Jun Feng, Xiaofei Jiang   +11 more
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Whole-genome sequencing reveals the genomic characterization and evolution of carbapenem-resistant Klebsiella pneumoniae in Gansu, China [PDF]

Frontiers in Cellular and Infection Microbiology
IntroductionKlebsiella pneumoniae has emerged as a major opportunistic pathogen, with rising antimicrobial resistance representing a critical public health concern.
Juanjuan Hou, Juan Liu, Mingliang Guo, Juan Li, Chen Qin, Guoping Zhang   +5 more
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Clinical evolution of ST11 carbapenem resistant and hypervirulent Klebsiella pneumoniae [PDF]

Communications Biology, 2021
AbstractCarbapenem-resistant and hypervirulent K. pneumoniae (CR-HvKP) strains that have emerged recently have caused infections of extremely high mortality in various countries. In this study, we discovered a conjugative plasmid that encodes carbapenem resistance and hypervirulence in a clinical ST86 K2 CR-HvKP, namely 17ZR-91. The conjugative plasmid
Miaomiao Xie, Xuemei Yang, Qi Xu, Lianwei Ye, Kaichao Chen, Zhiwei Zheng, Ning Dong, Qiaoling Sun, Lingbin Shu, Danxia Gu, Edward Wai-Chi Chan, Rong Zhang, Sheng Chen   +12 more
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Spread of ST11-O13/KL47 hypervirulent carbapenem-resistant Klebsiella pneumoniae isolates in China

Scientific Reports
Carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a serious threat to global public health. Hypervirulent CRKP (Hv-CRKP) can cause life-threatening infections, with significantly higher virulence and mortality compared to classical CRKP.
Zhiwei Liu, Huiwen Li, Tingting Li, Gongzhao Wang, Gang Li, Jing Wu, Pan Fu, Chuanqing Wang   +7 more
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Clinical Outcomes and Microbiological Characteristics of Sequence Type 11 Klebsiella pneumoniae Infection

Frontiers in Medicine, 2022
BackgroundSequence type 11 (ST11) Klebsiella pneumoniae (Kp) is highly prevalent in China and is a typical sequence type among KPC-producing isolates. This study aimed to evaluate the clinical outcomes and microbiological features of ST11 Kp infections ...
Ping Yang, Ping Yang, Zhenchao Wu, Chao Liu, Jiajia Zheng, Nan Wu, Zhangli Wu, Zhangli Wu, Juan Yi, Ming Lu, Ming Lu, Ning Shen, Ning Shen, Ning Shen   +13 more
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Emergence of colistin-resistant hypervirulent Klebsiella pneumoniae (CoR-HvKp) in China

Emerging Microbes and Infections, 2022
Colistin is regarded as a last-resort agent to combat infections caused by multidrug-resistant (MDR) Gram-negative bacteria, especially carbapenem-resistant isolates.
Xiaoyu Liu, Yarong Wu, Ying Zhu, Peiyao Jia, Xue Li, Xinmiao Jia, Wei Yu, Yujun Cui, Ruifu Yang, Wei Xia, Yingchun Xu, Qiwen Yang   +11 more
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The Origins of ST11 KL64 Klebsiella pneumoniae: a Genome-Based Study

Microbiology Spectrum, 2023
Carbapenem-resistant Klebsiella pneumoniae (CRKP) has emerged as a severe threat globally and is associated with increased lengths of hospital stay and high mortality in affected patients. The spread of CRKP is largely driven by a few dominant lineages, including ST11-KL64, the dominant type in China with a ...
Junna Wang, Yu Feng, Zhiyong Zong
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ST11, the dominant clone of KPC-producing Klebsiella pneumoniae in China [PDF]

Journal of Antimicrobial Chemotherapy, 2010
Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae has spread rapidly in China. In this study, we aimed to investigate the molecular epidemiology of KPC-producing K. pneumoniae isolates in China.Ninety-five carbapenem-resistant K. pneumoniae isolates from 13 hospitals in nine cities covering five provinces in China were analysed.
Yan, Qi, Zeqing, Wei, Shujuan, Ji, Xiaoxing, Du, Ping, Shen, Yunsong, Yu   +5 more
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Infection caused by Klebsiella pneumoniae ST11 in a patient after craniectomy [PDF]

Folia Microbiologica, 2019
Klebsiella pneumoniae infections have always been an important problem in public health, but today, the increasing resistance of these bacteria to antibiotics due to β-lactamases production has renewed interest in K. pneumoniae infections. The aim of the study was to present a case of a neurosurgical patient with multidrug-resistant K.
Ojdana, Dominika, Kochanowicz, Jan, Sacha, Paweł, Sieńko, Anna, Wieczorek, Piotr, Majewski, Piotr, Hauschild, Tomasz, Mariak, Zenon, Tryniszewska, Elżbieta   +8 more
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