Results 11 to 20 of about 14,120 (194)

Two ST11 Klebsiella pneumoniae strains exacerbate colorectal tumorigenesis in a colitis-associated mouse model [PDF]

Gut Microbes, 2021
Sequence type (ST) 11 is one of the major lineages of carbapenem-resistant Klebsiella pneumoniae (CRKP). Although the gastrointestinal (GI) carriage of CRKP predisposes individuals to subsequent infections, little is known for its impact on gut ...
Ming-Ko Chiang, Pei-Yi Hsiao, Yen-Yi Liu, Hui-Ling Tang, Chien-Shun Chiou, Min-Chi Lu, Yi-Chyi Lai   +6 more
doaj   +3 more sources

Emergence of ST11-K47 and ST11-K64 hypervirulent carbapenem-resistant Klebsiella pneumoniae in bacterial liver abscesses from China: a molecular, biological, and epidemiological study [PDF]

Emerging Microbes and Infections, 2020
Background: Multidrug-resistant bacteria, especially those with high virulence, are an emerging problem in clinical settings.Methods: We conducted a multicentre epidemiological and comparative genomic analysis on the evolution, virulence and ...
Qiwen Yang, Xinmiao Jia, Menglan Zhou, Hui Zhang, Wenhang Yang, Timothy Kudinha, Yingchun Xu   +6 more
doaj   +3 more sources

Expanding of ST11 Carbapenemase-Producing Klebsiella pneumoniae Subclones in a Chinese Hospital, Shenzhen, China

Infection and Drug Resistance, 2021
Min Zhang,1,2 Jia Li,3 Yuemei Lu,4 Weiyuan Wu,4 Jinsong Wu,4 Yanji Xu,1,5 Yuxin Zhong,1,2 Shiyi Liu,1,2 Chuchu Lin,6 Shuye Xu,3 Dandan Chen,1,2 Xuefeng Gao,7 Yutian Luo,8 Huaisheng Chen,8 Xueyan Liu,8 Wei Huang1,2 1Shenzhen People’s Hospital ...
Zhang M, Li J, Lu Y, Wu W, Wu J, Xu Y, Zhong Y, Liu S, Lin C, Xu S, Chen D, Gao X, Luo Y, Chen H, Liu X, Huang W   +15 more
doaj   +5 more sources

Worldwide transmission of ST11-KL64 carbapenem-resistant Klebsiella pneumoniae: an analysis of publicly available genomes

mSphere, 2023
ST11-KL64 is an internationally distributed lineage of carbapenem-resistant Klebsiella pneumoniae and is the most common type in China. The international and interprovincial (in China) transmission of ST11-KL64 CRKP remains to be elucidated. We used both
Junna Wang, Yu Feng, Zhiyong Zong
doaj   +3 more sources

Analysis of the Association Between Antimicrobial Resistance Genes and Virulence Factors in ST11 and Non-ST11 CR-KP Bloodstream Infections in the Intensive Care Unit

Infection and Drug Resistance
Yanye Tu,1 Hui Gao,1 Rongqing Zhao,1 Jiliang Yan,1 Diyu Wu2 1Clinical Laboratory of Ningbo Medical Centre Lihuili Hospital, Ningbo University, Ningbo, Zhejiang Province, People’s Republic of China; 2School of Laboratory Medicine and Life Science, Wenzhou
Tu Y, Gao H, Zhao R, Yan J, Wu D
doaj   +3 more sources

Disease Susceptibility to ST11 Complex Meningococci Bearing Serogroup C or W135 Polysaccharide Capsules, North America

Emerging Infectious Diseases, 2004
Clusters of meningococcal disease caused by a hyperinvasive lineage of Neisseria meningitidis, the ST11 complex, bearing a serogroup C polysaccharide capsule, have been prominent in Europe and North America since the early 1990s.
Andrew J. Pollard, Jan Ochnio, Margaret Ho, Martin Callaghan, Mark Bigham, Simon Dobson   +5 more
doaj   +4 more sources

Comparative Proteomic Profiling of Clinical <i>Klebsiella pneumoniae</i> Strains and the Corresponding Outer Membrane Vesicles. [PDF]

J Extracell Biol
ABSTRACT Klebsiella pneumoniae (K. pneumoniae) has become a global threat due to the convergence of carbapenem resistance and hypervirulence. Outer membrane vesicles (OMVs) play important roles in bacterial pathogenicity, yet their functional coordination with strains remains unclear.
Li Z, Xi J, Jia X, He Y, Wang G, Chen S, Chu X, Zhang Q, Zhu Y, Yu W, Jia P, Liu X, Yang Q.   +12 more
europepmc   +2 more sources

Clinical evolution of ST11 carbapenem resistant and hypervirulent Klebsiella pneumoniae [PDF]

Communications Biology, 2021
AbstractCarbapenem-resistant and hypervirulent K. pneumoniae (CR-HvKP) strains that have emerged recently have caused infections of extremely high mortality in various countries. In this study, we discovered a conjugative plasmid that encodes carbapenem resistance and hypervirulence in a clinical ST86 K2 CR-HvKP, namely 17ZR-91. The conjugative plasmid
Miaomiao Xie, Xuemei Yang, Qi Xu, Lianwei Ye, Kaichao Chen, Zhiwei Zheng, Ning Dong, Qiaoling Sun, Lingbin Shu, Danxia Gu, Edward Wai-Chi Chan, Rong Zhang, Sheng Chen   +12 more
openaire   +4 more sources

Emergence of colistin-resistant hypervirulent Klebsiella pneumoniae (CoR-HvKp) in China

Emerging Microbes and Infections, 2022
Colistin is regarded as a last-resort agent to combat infections caused by multidrug-resistant (MDR) Gram-negative bacteria, especially carbapenem-resistant isolates.
Xiaoyu Liu, Yarong Wu, Ying Zhu, Peiyao Jia, Xue Li, Xinmiao Jia, Wei Yu, Yujun Cui, Ruifu Yang, Wei Xia, Yingchun Xu, Qiwen Yang   +11 more
doaj   +1 more source

Whole Genome Sequencing Reveals High Prevalence of Antimicrobial Resistance Genes in <i>Salmonella</i> Isolates From Diarrheal Patients in Jinan, China. [PDF]

Can J Infect Dis Med Microbiol
Background The global emergence of multidrug‐resistant (MDR) Salmonella enterica poses a significant public health threat, particularly in developing countries where antibiotic consumption remains high. However, genomic data on circulating Salmonella strains in Eastern China remain limited.
Ma C, Li N, Wang L, Li K, Liu M, Zhou J, Liu H.   +6 more
europepmc   +2 more sources