Results 11 to 20 of about 30,785 (250)
The role of ST2 and ST2 genetic variants in schistosomiasis [PDF]
Chronic schistosomiasis and its severe complication, periportal fibrosis, are characterized by a predominant Th2 response. To date, specific single nucleotide polymorphisms in ST2 have been some of the most consistently associated genetic variants for asthma.We investigated the role of ST2 (a receptor for the Th2 cytokine IL-33) in chronic and late ...
Li Gao, Huifang Liang, Jianping Zhao
exaly +5 more sources
ST2 IN REJECTION OF THE TRANSPLANTED HEART [PDF]
This review summarizes the current literature devoted to the analysis of prognostic role of ST2 biomarker in rejection of the transplanted heart. ST2 is one of the most promising diagnostic markers of the development and severity of heart failure as well
O. P. Shevchenko +3 more
doaj +6 more sources
Performance Evaluation of AFIAS ST2 and Ichroma ST2 Assays in Comparison with Presage ST2 Assay
Background: Elevated soluble suppression of tumorigenicity 2 (sST2) levels may predict mortality in heart failure (HF) patients. The AFIAS ST2 assay (AFIAS ST2, Boditech Med Inc., Chuncheon, Korea) and ichroma ST2 assay (ichroma ST2, Boditech Med Inc ...
Hanah Kim +6 more
doaj +3 more sources
Cardiovascular diseases are leading cause of mortality and morbidity, and are responsible for 1 out of every 6 deaths in the United States.1 Cardiac remodeling is an important determinant of long term outcomes and occurrence of heart failure (HF). Many times one requires additional tools like biomarkers to identify high risk individuals, to diagnose ...
Aditi Dattagupta, Sathyamurthy Immaneni
openaire +4 more sources
Profiling of Tregs across tissues reveals plasticity in ST2 expression and hierarchies in tissue-specific phenotypes [PDF]
Summary: Foxp3+ regulatory T cells (Tregs) are critical mediators of peripheral tolerance and immune homeostasis and exert tissue-specific functions. In many nonlymphoid tissues, Tregs show enriched expression of the IL-33 receptor ST2.
Sabine Spath +4 more
doaj +2 more sources
The ST2+ Treg/amphiregulin axis protects from immune-mediated hepatitis [PDF]
IntroductionThe alarmin IL-33 has been implicated in the pathology of immune-mediated liver diseases. IL-33 activates regulatory T cells (Tregs) and type 2 innate lymphoid cells (ILC2s) expressing the IL-33 receptor ST2.
Selina Wachtendorf +10 more
doaj +3 more sources
The search for novel biomarkers in sepsis-induced cardiomyopathy – A new challenge to overcome [PDF]
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection and it remains the most frequent cause of death amongst critically ill patients worldwide, despite recent medical advancements.
Cristian Sorin Prepeliuc +7 more
doaj +1 more source
Dynamics of NT-proBNP and ST2 levels as markers of heart failure in patients with endogenous Cushing syndrome (hypercortisolism) [PDF]
Aim. To evaluate frequency of heart failure syndrome in patients with endogenous hypercortisolism and to establish relationship between effective treatment for hypercortisolism and regression of heart failure with particular emphasis on the observation ...
Raisa S. Kosharnaia +4 more
doaj +1 more source
Aim. To develop a predictive model of the risk of adverse outcomes within 12 months after myocardial infarction (MI) in patients over 70 years of age with frailty syndrome.Material and methods.
O. Yu. Aidumova +2 more
doaj +1 more source
Sex-Specific Thresholds for Cardiac Biomarkers—We Need to Move Forward
Cardiovascular biomarkers play a major diagnostic role for cardiologists. Different biomarkers provide different insights into a variety of cardiovascular conditions and in doing so they improve diagnosis and management.
Ronstan Lobo, Allan S. Jaffe
doaj +1 more source

