Results 11 to 20 of about 33,191 (261)

ST2 IN REJECTION OF THE TRANSPLANTED HEART [PDF]

open access: yesВестник трансплантологии и искусственных органов, 2016
This review summarizes the current literature devoted to the analysis of prognostic role of ST2 biomarker in rejection of the transplanted heart. ST2 is one of the most promising diagnostic markers of the development and severity of heart failure as well
O. P. Shevchenko   +3 more
doaj   +4 more sources

Profiling of Tregs across tissues reveals plasticity in ST2 expression and hierarchies in tissue-specific phenotypes

open access: yesiScience, 2022
Summary: Foxp3+ regulatory T cells (Tregs) are critical mediators of peripheral tolerance and immune homeostasis and exert tissue-specific functions. In many nonlymphoid tissues, Tregs show enriched expression of the IL-33 receptor ST2.
Sabine Spath   +4 more
doaj   +2 more sources

ST2: Current status

open access: yesIndian Heart Journal, 2018
Cardiovascular diseases are leading cause of mortality and morbidity, and are responsible for 1 out of every 6 deaths in the United States.1 Cardiac remodeling is an important determinant of long term outcomes and occurrence of heart failure (HF). Many times one requires additional tools like biomarkers to identify high risk individuals, to diagnose ...
Aditi Dattagupta, Sathyamurthy Immaneni
openaire   +4 more sources

The ST2+ Treg/amphiregulin axis protects from immune-mediated hepatitis [PDF]

open access: yesFrontiers in Immunology
IntroductionThe alarmin IL-33 has been implicated in the pathology of immune-mediated liver diseases. IL-33 activates regulatory T cells (Tregs) and type 2 innate lymphoid cells (ILC2s) expressing the IL-33 receptor ST2.
Selina Wachtendorf   +10 more
doaj   +2 more sources

IL-33–ST2 signaling promotes stemness in subtypes of myeloid leukemia cells through the Wnt and Notch pathways [PDF]

open access: yes, 2023
Cell stemness is characterized by quiescence, pluripotency, and long-term self-renewal capacity. Therapy-resistant leukemic stem cells (LSCs) are the primary cause of relapse in patients with chronic and acute myeloid leukemia (CML and AML). However, the
Gabriela M. Baerlocher   +17 more
core   +1 more source

Soluble ST2 is regulated by p75 neurotrophin receptor and predicts mortality in diabetic patients with critical limb ischemia [PDF]

open access: yes, 2012
<b>Objective—</b><p></p> The p75 neurotrophin receptor (p75<sup>NTR</sup>) contributes to diabetes mellitus−induced defective postischemic neovascularization.
Spinetti, Gaia   +34 more
core   +1 more source

Disordered IL-33/ST2 activation in decidualizing stromal cells prolongs uterine receptivity in women with recurrent pregnancy loss [PDF]

open access: yes, 2012
Decidualization renders the endometrium transiently receptive to an implanting blastocyst although the underlying mechanisms remain incompletely understood.
Nicou, M   +88 more
core   +2 more sources

IL-33/ST2 Axis in Organ Fibrosis [PDF]

open access: yes, 2018
Interleukin 33 (IL-33) is highly expressed in barrier sites, acting via the suppression of tumorigenicity 2 receptor (ST2). IL-33/ST2 axis has long been known to play a pivotal role in immunity and cell homeostasis by promoting wound healing and tissue ...
Ourania S. Kotsiou   +2 more
core   +2 more sources

Soluble ST2 associates with diabetes but not established cardiovascular risk factors: a new inflammatory pathway of relevance to diabetes? [PDF]

open access: yes, 2012
Preliminary data mostly from animal models suggest the sST2/IL-33 pathway may have causal relevance for vascular disease and diabetes and thus point to a potential novel inflammatory link to cardiometabolic disease.
Kevin A. Deans (125089)   +104 more
core   +2 more sources

The Diagnostic and Prognostic Value of Soluble ST2 in Sepsis [PDF]

open access: yesFrontiers in Medicine, 2021
Abstract Objective: To determine the diagnostic and prognostic value of soluble ST2 (sST2) in patients with sepsis. Methods: A total of 113 critically ill patients were enrolled from the emergency department of the Beijing Chaoyang Hospital Jing Xi Branch.
Xinghua Ye   +11 more
openaire   +3 more sources

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