Results 101 to 110 of about 26,038 (246)

Phase I Metabolism of Novel Phencyclidine Derivative 3‐Cl‐PCP: In Vitro Studies With Pooled Human Liver Microsomes and Investigation of a Post‐Mortem Case

open access: yesDrug Testing and Analysis, EarlyView.
A fatal 3‐chloro‐phencyclidine (3‐Cl‐PCP) intoxication was investigated by analyzing postmortem samples and a pooled human liver microsomes assay. Tentative metabolite identification was performed by liquid chromatography‐quadrupole time‐of‐flight mass spectrometry (LC‐QTOF‐MS). Seven phase I metabolites were identified.
Johannes Kutzler   +3 more
wiley   +1 more source

Stable isotope dilution assay for the accurate determination of mycotoxins in maize by UHPLC-MS/MS. [PDF]

open access: yesAnal Bioanal Chem, 2012
Varga E   +7 more
europepmc   +1 more source

Investigations Into the Metabolism and Elimination of Tesofensine in Human Urine

open access: yesDrug Testing and Analysis, EarlyView.
This study investigated tesofensine metabolism and urinary elimination after a single 483 μg intake via a dietary supplement. In six volunteers, urine was collected up to 659 h. LC‐HRMS/MS identified four tentative metabolites; maximum urinary concentrations reached 4 ng/mL within 4–48 h.
O. Krug, A. Thomas, M. Thevis
wiley   +1 more source

Identification of Synthetic Urine by Analysis of Stable Carbon and Nitrogen Isotope Ratios and Comparison to Established GC‐MS/MS and LC‐MS/MS Analysis

open access: yesDrug Testing and Analysis, EarlyView.
This study compared GC‐MS/MS, EA‐IRMS, and LC‐MS/MS for detecting synthetic and manipulated urine samples in doping control and forensic analysis. EA‐IRMS proved particularly effective for identifying mixtures of synthetic and authentic urine, providing a reliable complement to established authenticity testing methods.
Frank Hülsemann   +4 more
wiley   +1 more source

Cannabidiol in Anorexia Nervosa: A Double‐Blind Randomized Placebo Controlled Pilot Study to Test Safety, Pharmacokinetics, and Symptom Change

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder marked by an intense fear of gaining weight and persistent body dissatisfaction, both during periods of underweight and after weight restoration. The endocannabinoid system may offer therapeutic benefits, particularly in reducing anxiety.
Neha Sahota   +8 more
wiley   +1 more source

Solar Fuels Via Methane Valorization: Thermochemical Pathways, Unified Metrics, and Techno‐Economic Perspectives

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A first‐of‐its‐kind review benchmarks three solar methane valorization pathways with unified performance metrics for clean fuel production. Meeting global climate targets and sustainable energy demands requires carbon‐neutral fuels and innovative conversion pathways.
Muhammad Abdulmoez   +3 more
wiley   +1 more source

Origin of Physicochemical and Mechanical Stability of Low‐Temperature Prepared TiO2‐Based Photocatalytic Films: Surface Hydroxyl Density Matching

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Material science advances show how surface chemistry improves low‐temperature prepared TiO2‐SiO2 composite films. Using a colloidal‐based synthesis method instead of a powdered‐based one, researchers exploit hydroxyl groups' interfacial interactions to create nanoscale structures with superior physicochemical and mechanical stability.
Andraž Šuligoj   +7 more
wiley   +1 more source

Strategies for Identification and Mitigation of Sanguinarine in Mustard Oil Adulterated by Argemone—A Comprehensive Review

open access: yesFood Chemistry International, EarlyView.
Sanguinarine, a toxic alkaloid present in argemone, can lead to epidemic dropsy or chronic diseases through DNA intercalation and immune system suppression. Regulatory efforts face challenges due to economic motivations for adulteration as well as technical, social, and infrastructure barriers.
Gururaj Pejavara Narayana   +4 more
wiley   +1 more source

Evaluation of sunn hemp performance and nutritive value in Maine, USA

open access: yesGrassland Research, EarlyView.
Abstract Background Sunn hemp (Crotalaria juncea L. and Crotalaria ochroleuca G. Don) was evaluated as a warm‐season legume to mitigate the “summer slump” in Maine's forage production caused by heat and moisture deficit stress. Methods This study compared three cultivars: “Crescent Sunn,” “Loei,” and “Red Mini,” at 60 and 90 days after seeding over the
Jaime Garzon, Edgar Cardenas
wiley   +1 more source

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