Results 71 to 80 of about 171,178 (245)
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer +14 more
wiley +1 more source
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
Numerical Analysis of Flow in U-Type Solid Oxide Fuel Cell Stacks
EnergiesNumerical analysis of a U-type solid oxide fuel cell stack was performed using computational fluid dynamics to investigate the effects of stack capacities and fuel/air utilization rates on the internal flow uniformity.
Hao Yuan Yin +5 more
doaj +1 more source
EFSA Journal, 2015 Single events MON 87708 and MON 89788 were combined to produce the stack two‐event soybean MON 87708 × MON 89788. The EFSA GMO Panel previously assessed the two single events and did not identify safety concerns in the context of their scope. No new data
EFSA Panel on Genetically Modified Organisms (GMO)
doaj +1 more source
PENGARUH PANJANG STACK SELUBUNG KABEL TERHADAP PERUBAHAN SUHU PADA SISTEM PENDINGIN TERMOAKUSTIK
Spektra: Jurnal Fisika dan Aplikasinya, 2017 Research on environmentally friendly thermo-acoustic coolants uses a heat exchanger from the cable sheath material. The resonator tube used in the thermoelectric cooler is a 5.25 cm diameter PVC (polyvinyl chloride) tube with a length of 87 cm ...
Indah Kharismawati, Hanif Rafika Putri
doaj +1 more source
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Trajectories of Physical Function in Canadian Children with Juvenile Idiopathic Arthritis
Arthritis Care &Research, Accepted Article.Objectives We describe trajectories of physical function in children newly diagnosed with juvenile idiopathic arthritis (JIA) and identify trajectories with persisting functional impairments and associated baseline characteristics. Methods We included patients enrolled in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry ...
Clare Cunningham +14 more
wiley +1 more source
Hidden Abstract Stack Markov Models with Learning Process
MathematicsWe present hidden abstract stack Markov models (HASMMs) with their learning process. The HASMMs we offer carry the more expressive nature of probabilistic context-free grammars (PCFGs) while allowing faster parameter fitting of hidden Markov models (HMMs)
Mete Özbaltan
doaj +1 more source
A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems
International Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam +2 more
wiley +1 more source