Results 81 to 90 of about 478,710 (331)
Single-Cell Labeling Strategies to Dissect Neuronal Structures and Local Functions
Biology, 2023 The brain network consists of ten billion neurons and is the most complex structure in the universe. Understanding the structure of complex brain networks and neuronal functions is one of the main goals of modern neuroscience. Since the seminal invention
Keigo Kohara, Masayoshi Okada
doaj +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Arquivos de Gastroenterologia, 2019 BACKGROUND: Esophageal cancer is the eighth most common cancer. The prognosis is bleak in patients with advanced stages. Patients with early disease have a better prognosis than those with advanced stage.
Jean Félix PIÑERÚA-GONSÁLVEZ +2 more
doaj +1 more source
Loss of neurons from laminas I-III of the spinal dorsal horn is not required for development of tactile allodynia in the spared nerve injury model of neuropathic pain [PDF]
, 2005 It has been proposed that death of inhibitory interneurons in the dorsal horn contributes to the neuropathic pain that follows partial nerve injury. In this study, we have used two approaches to test whether there is neuronal death in the dorsal horn in ...
Arham, A.Z. +3 more
core +2 more sources
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Interfacial polymerization for colorimetric labeling of protein expression in cells. [PDF]
PLoS ONE, 2014 Determining the location of rare proteins in cells typically requires the use of on-sample amplification. Antibody based recognition and enzymatic amplification is used to produce large amounts of visible label at the site of protein expression, but ...
Jacob L Lilly +5 more
doaj +1 more source
Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling [PDF]
, 2003 Background— Transplantation of endothelial progenitor cells (EPCs) improves vascularization and left ventricular function after experimental myocardial ischemia.
Aicher, A +9 more
core +1 more source
Multiplexed Plasmonic Nano-Labeling for Bioimaging of Cytological Stained Samples [PDF]
, 2021 Paule Marcoux-Valiquette +8 more
openalex +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
The tip-link antigen, a protein associated with the transduction complex of sensory hair cells, is protocadherin-15 [PDF]
, 2006 Sound and acceleration are detected by hair bundles, mechanosensory structures located at the apical pole of hair cells in the inner ear. The different elements of the hair bundle, the stereocilia and a kinocilium, are interconnected by a variety of link
Ahmed, Zubair M +14 more
core +2 more sources