The Role of Stargazin in the Pathogenesis of Psychiatric Disorders
Psychiatric disorders including intellectual disabilities and mood and affective disorders affect around one quarter of the general population. Schizophrenia and intellectual disability have been consistently associated to both cognitive and social impairment as a putative consequence of impaired synaptic function. However, although numerous genes have
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Convergence and divergence of molecular mechanisms in Hebbian and homeostatic plasticity. [PDF]
Feighan KM +3 more
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Activation of silent synapses driven by emerging technologies: mechanisms, disease associations, and prospects for clinical translation. [PDF]
Li Y +8 more
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Orthogonal RNA-regulated destabilization domains for three-color RNA imaging with minimal RNA perturbation. [PDF]
Pham TG +5 more
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Arc weakens synapses by dispersing AMPA receptors from postsynaptic density via modulating PSD phase separation. [PDF]
Chen X +6 more
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The mouse stargazer gene encodes a neuronal Ca2+-channel gamma subunit [see comments]
Stargazer mice have spike-wave seizures characteristic of absence epilepsy, with accompanying defects in the cerebellum and inner ear. We describe here a novel gene, Cacng2, whose expression is disrupted in two stargazer alleles.
Biddlecome, G H +9 more
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Local RhoA activation induces anillin-independent septin recruitment in interphase cells. [PDF]
Chandrasekar S +5 more
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Dissertação de Mestrado em Biologia Celular e Molecular apresentada à Faculdade de Ciências e TecnologiaA plasticidade sináptica que ocorre ao nível das sinapses excitatórias é um dos mecanismos cerebrais mais importantes para um normal desenvolvimento ...
Rondão, Tiago Batista Abrantes
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Huntingtin and its allies at the cortico-striatal synapse. [PDF]
Zuccato C, Scolz A, Iennaco R.
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GluR2Q and GluR2R AMPA Subunits are not Targets of lypd2 Interaction. [PDF]
Lauriello A, McVeigh Q, Sung RJ.
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