Results 131 to 140 of about 1,561 (160)

Targeting phase separation: a promising treatment option for hepatocellular carcinoma. [PDF]

Cell Commun Signal
Zhou Z, Jin S, Li X, Zhang D, Zhang S, Zhou H, Cai J, Song T, Wang X, Kong Q, Tang Z, Tan J, Zhang J.   +12 more
europepmc   +1 more source

The impact of subunit type, alternative splicing, and auxiliary proteins on AMPA receptor trafficking. [PDF]

J Biol Chem
Couch T, McCullock TW, MacLean DM.
europepmc   +1 more source

ATLAS: a rationally designed anterograde transsynaptic tracer. [PDF]

Nat Methods
Rivera JF, Huang H, Weng W, Sohn H, Girasole AE, Li S, Albanese MA, Qin M, Tao C, Klug ME, Rao S, Paletzki R, Herring BE, Kanoski SE, Zhang LI, Gerfen CR, Sabatini BL, Arnold DB.   +17 more
europepmc   +1 more source

CYFIP1 governs the development of cortical axons by modulating calcium availability. [PDF]

Nat Commun
Ricci C, Midroit MJ, Caicci F, Achsel T, Domínguez-Iturza N, Bagni C.   +5 more
europepmc   +1 more source

The role of the Stargazin-like protein gamma 7.

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Stargazin modulates AMPA receptor antagonism

Neuropharmacology, 2008
AMPA receptors mediate the majority of fast synaptic transmission and underlie several forms of synaptic plasticity. AMPARs also have an important role in several neuronal pathologies. Therefore, studying the structure and function of these receptors is important for understanding general mechanisms of synaptic transmission as well as for the ...
Valentin Stein
exaly   +4 more sources

A novel action of stargazin as an enhancer of AMPA receptor activity

Neuroscience Research, 2004
Stargazin (gamma-2) is disrupted in the ataxic and epileptic mutant mouse, stargazer (stg). The striking defect in the stg cerebellum is the lack of functional AMPA receptors on granule cells. Recently, it has been reported that gamma-2 and its related molecules are crucial for the surface expression, synaptic targeting and recycling of AMPA receptors,
Masahiko Watababe, Masahiro Fukaya, Masanobu Kano   +2 more
exaly   +4 more sources

Molecular Mechanism of AMPA Receptor Modulation by TARP/Stargazin [PDF]

Neuron, 2017
AMPA receptors (AMPARs) mediate the majority of fast excitatory transmission in the brain and critically contribute to synaptic plasticity and pathology. AMPAR trafficking and gating are tightly controlled by auxiliary transmembrane AMPAR regulatory proteins (TARPs).
Mohammad S Qneibi, Moshe Gillor, Yael Stern-Bach   +2 more
exaly   +3 more sources

Calpain-mediated regulation of stargazin in adult rat brain [PDF]

Neuroscience, 2011
Changes in AMPA receptors have been proposed to underlie changes in synaptic efficacy in hippocampus and other brain structures. Calpain activation has also been discussed as a potential mechanism to produce lasting modifications of synaptic structure and function.
Xiaoning Bi, Michel Baudry
exaly   +3 more sources

Bidirectional Synaptic Plasticity Regulated by Phosphorylation of Stargazin-like TARPs [PDF]

Neuron, 2005
Synaptic plasticity involves protein phosphorylation cascades that alter the density of AMPA-type glutamate receptors at excitatory synapses; however, the crucial phosphorylated substrates remain uncertain. Here, we show that the AMPA receptor-associated protein stargazin is quantitatively phosphorylated and that stargazin phosphorylation promotes ...
Susumu Tomita, Roger Nicoll, Valentin Stein   +2 more
exaly   +3 more sources