Results 131 to 140 of about 1,542 (158)
The impact of subunit type, alternative splicing, and auxiliary proteins on AMPA receptor trafficking. [PDF]
Couch T, McCullock TW, MacLean DM.
europepmc +1 more source
CYFIP1 governs the development of cortical axons by modulating calcium availability. [PDF]
Ricci C +5 more
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ATLAS: a rationally designed anterograde transsynaptic tracer. [PDF]
Rivera JF +17 more
europepmc +1 more source
Membrane Protein Modulators in Neuroinflammation. [PDF]
Chen L +5 more
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Learning from stargazin: the mouse, the phenotype and the unexpected
The stargazin gene (also referred to as Cacng2) has been identified by forward genetics in a spontaneous mouse mutant with ataxic gait, upward head-elevating movements (hence the name stargazer for the mouse) and episodes of spike-wave discharges. Stargazin is related to the gamma-1 subunit of skeletal muscle voltage-dependent calcium channel (VDCC ...
Osten, P., Stern-Bach, Y.
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Stargazin involvement with bipolar disorder and response to lithium treatment
Multiple reports have implicated chromosomal region 22q13.1 in both schizophrenia and bipolar disorder. The calcium channel gamma-2 subunit gene (cacng2, Stargazin) located on 22q13.1 was recently reported to be associated with schizophrenia. We aimed to examine the expression levels of Stargazin in post-mortem brain samples of patients with ...
Silberberg, G +9 more
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Stargazin modulates AMPA receptor antagonism
Neuropharmacology, 2008AMPA receptors mediate the majority of fast synaptic transmission and underlie several forms of synaptic plasticity. AMPARs also have an important role in several neuronal pathologies. Therefore, studying the structure and function of these receptors is important for understanding general mechanisms of synaptic transmission as well as for the ...
Valentin Stein
exaly +4 more sources
Stargazin interacts functionally with the AMPA receptor glutamate-binding module
Neuropharmacology, 2007Neuronal AMPA receptors comprise pore forming glutamate receptor (GluR) proteins and auxiliary transmembrane AMPA receptor regulatory (TARP) subunits. TARPs traffic AMPA receptors to synapses and regulate channel gating. Both intracellular and extracellular regions in TARPs regulate AMPA receptors; however, the details for these interactions remain ...
Yuko Fukata +2 more
exaly +3 more sources
Stargazin modulates AMPA receptor gating and trafficking by distinct domains
Nature, 2005AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid) receptors mediate fast excitatory synaptic transmission in the brain. These ion channels rapidly deactivate and desensitize, which determine the time course of synaptic transmission. Here, we find that the AMPA receptor interacting protein, stargazin, not only mediates AMPA receptor ...
Susumu Tomita, Roger Nicoll
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