Results 291 to 300 of about 250,824 (344)

Fedratinib reveals chemotherapeutic potential in esophageal squamous cell cancer. [PDF]

Front Pharmacol
Luo M, Zhu J, Yang Y, Liao C, Liu X, Tang M, Xu L, Zhong X, Ma Q, Guo X.   +9 more
europepmc   +1 more source

Phloretin Suppresses Preadipocyte Differentiation by Targeting PPARγ/Transferrin to Activate Ferroptosis Signaling Pathway

Food Frontiers, EarlyView.
Phloretin alleviates HFD‐induced obesity and suppresses adipogenesis by activating the ferroptosis pathway, potentially via targeting PPARγ and transferrin. ABSTRACT Phloretin, a plant‐derived dihydrochalcone bioactive compound, potentially modulates preadipocyte differentiation, although this remains controversial and requires further clarification ...
Jie Li, Qihui Zhu, Yang Li, Haiyu Zhao, Yi Bi, Chuanying Pan, Min Wang, Lin Han, Xianyong Lan   +8 more
wiley   +1 more source

STAT3 c.1915C > T variant-associated Hyper-IgE syndrome in a child: a case report. [PDF]

Front Pediatr
Dai Q, Wang Y, Wang Z, Ru L.
europepmc   +1 more source

Canned Foods: Evolution, Benefits, and Health Implications of Modern Packaging

Food Safety and Health, EarlyView.
This graphical abstract presents a concise visual overview of canned food technology, highlighting its historical evolution, key benefits, and associated health risks. It integrates timelines, icons, and summary points to clearly communicate advancements in preservation, consumer advantages, and potential safety concerns in a single schematic ...
Shaswati Rout, Priyadarsini Sahoo, Anuprita Ray, Shuvendu Shekhar Mohapatra   +3 more
wiley   +1 more source

Inhibition of FOS-Like Antigen 1 Reduces Chemoresistance to Temozolomide Through Stemness Reprogramming via IL-6/STAT3^Tyr705 Pathway. [PDF]

MedComm (2020)
Sim J, Park J, Heo J, Kim YJ, Kim D, Jeon YH, Lee JE, Choi SH, Kim HJ, Hwang SJ, Kim J, Cho KG, Yoo J, Moon JH, Moon JS, Sung KS, Lim J.   +16 more
europepmc   +1 more source

Genomic and Immune Correlates of EZH2 Expression and Activity in Olfactory Neuroblastoma

Head &Neck, EarlyView.
ABSTRACT Purpose Olfactory neuroblastoma (ONB) is a rare sinonasal malignancy with limited therapeutic options in the recurrent/metastatic setting; little is known regarding its responsiveness to immunotherapy. Inhibition of enhancer of zeste homolog 2 (EZH2) has been shown to improve T‐cell‐mediated killing and susceptibility to immune checkpoint ...
Elisabetta Xue, Tolulope Adeyelu, Harris Krause, Andrew Elliott, Ranee Mehra, Heloisa Soares, Emil Lou, Ari Vanderwalde, David Spetzler, Dara Bracken‐Clarke, Nyall R. London Jr., James L. Gulley, Charalampos S. Floudas   +12 more
wiley   +1 more source

Targeting the JAK/STAT Signaling Pathway in Breast Cancer: Leaps and Hurdles. [PDF]

Biomedicines
Aho S, Coste C, Purcari L, Trédan O, Poulard C, Mery B, Boisvert FM, Le Romancer M.   +7 more
europepmc   +1 more source

BRUCE liver-KO enhances MASLD/MASH development in the steatotic PTEN-KO background by impairing mitochondrial metabolism and activating STAT3. [PDF]

Cell Death Dis
Che L, Stevenson CK, Plas DR, Wang J, Du C.   +4 more
europepmc   +1 more source

Very-early-onset autoimmune hypothyroidism: a report of two cases with STAT3 gain-of-function variant. [PDF]

Eur Thyroid J
Ravi R, Niskanen A, Reeve MP, Makkonen K, Niinikoski H, Toppari J, Kero J.   +6 more
europepmc   +1 more source

Stat3 mediates Fyn kinase-driven dopaminergic neurodegeneration and microglia activation

Disease Models & Mechanisms
Sahiba Siddiqui, Fang Liu, Anumantha G. Kanthasamy, Maura McGrail   +3 more
doaj   +1 more source