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Gan to kagaku ryoho. Cancer & chemotherapy, 2011
Clinical efficacies of various molecular-targeted drugs have been recently demonstrated. Most of these drugs are kinase inhibitors. A most successful drug Glivec is an inhibitor of Bcr-Abl fusion kinase, derived from a well-known causative chromosome translocation of chronic myeloid leukemia(CML). Although other kinase inhibitors have also proved to be
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Clinical efficacies of various molecular-targeted drugs have been recently demonstrated. Most of these drugs are kinase inhibitors. A most successful drug Glivec is an inhibitor of Bcr-Abl fusion kinase, derived from a well-known causative chromosome translocation of chronic myeloid leukemia(CML). Although other kinase inhibitors have also proved to be
openaire +1 more source
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
Nature Reviews. Cancer, 2014Hua Yu +4 more
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Therapeutically exploiting STAT3 activity in cancer — using tissue repair as a road map
Nature Reviews. Cancer, 2018J. Huynh, A. Chand, D. Gough, M. Ernst
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