Results 211 to 220 of about 8,110,573 (262)

JAK/STAT signaling pathway inhibitors in neurodegenerative diseases: current status and future perspectives. [PDF]

Front Aging Neurosci
Yang HX, Su BW, Bao YN, Wang WH, Lao JY, Ji HY, Han S, Cui XH, Ren HW, Luan ZL.   +9 more
europepmc   +1 more source

Multi-genomics data mining identified critical transcription factors and immune response pathways in traumatic optic nerve injury and retinal injury. [PDF]

Front Ophthalmol (Lausanne)
Li J, Zhang Y, Zhou S.
europepmc   +1 more source

JAK-STAT signaling pathway in cancer: from molecular mechanisms to clinical intervention. [PDF]

Mol Cancer
Zhang X, Li P, Ma F, Wang T, Chu Q, Wei S, Xue C, Wang Z, Lu J.   +8 more
europepmc   +1 more source

Optineurin Restricts ZIKV Replication Through Promoting IFN-Mediated JAK/STAT Signaling Pathway. [PDF]

J Med Virol
Huang Y, Ye H, Lai M, Xie H, Sun J, Chen L.   +5 more
europepmc   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Natural product derived phytochemicals as modulators of cancer stemness and drug resistance. [PDF]

Front Oncol
Qazi AK, Parray MO, Syed SH.
europepmc   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

One virus-many strategies: type-specific interactions between human adenoviruses and innate immunity. [PDF]

J Virol
Hanrieder L, Schreiner S.
europepmc   +1 more source

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source