Results 221 to 230 of about 207,642 (299)

Identification of <i>Drosophila melanogaster</i> as a model organism in COPD research. [PDF]

Front Immunol
Zhang Y, Kou J, Zhang Y, Huang H, Yang Y, Liu C, Lu T, Zhao X, Liu Y, He J.   +9 more
europepmc   +1 more source

PRMT5 Mediates Sepsis‐Associated Lung Injury by Modulating JAK1 Arginine Methylation: A Mechanism Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Lung injury is a common complication in critical sepsis. PRMT5 is implicated in endothelial inflammation and lung diseases, but its role in sepsis‐associated lung injury remains unclear. This study collected clinical sepsis samples and detected the mRNA expression of PRMT5.
Bo Wang, Zhen Ge, Fei‐Xiang Chen
wiley   +1 more source

Epigenomic control of immunity: from mechanisms to therapeutic targets in inflammatory bowel diseases. [PDF]

Int Immunol
Shih HY, Sciumè G, Mikami Y.
europepmc   +1 more source

LncRNA NORAD Enhances Inflammatory Injury in Sepsis‐Associated Acute Lung Damage Through miR‐150‐5p/STAT1‐Dependent NF‐κB Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute lung injury (ALI) is a severe complication of sepsis, yet the role of lncRNA NORAD in its pathogenesis remains unclear. Using LPS‐stimulated BEAS‐2B and HBEC3‐KT cells as well as cecal ligation and puncture (CLP)‐induced ALI models in C57BL/6 mice, we found that NORAD expression was markedly upregulated and promoted cell injury ...
Han Liu, Xi‐Xi Chen, Gui‐Hua Wei, Feng Li, Hai‐Yan Zong   +4 more
wiley   +1 more source

Topical Astaxanthin Attenuates Imiquimod-Induced Psoriasiform Dermatitis by Downregulating Psoriasis-Associated Keratin Gene Expression (Krt16, Krt17, Krt6a) and Inhibiting the JAK-STAT Signaling Pathway. [PDF]

Molecules
Albahadly WKY, Al-Saedi HFS, Ashoor JA, Rasool MI, Hasan SA, ALtrufi MH.   +5 more
europepmc   +1 more source

LINC01605 Predicts the Poor Prognosis of Non‐Small Cell Lung Cancer and Promotes Chemotherapy Resistance by Regulating miR‐7111‐5p/ELK1

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Non‐small cell lung cancer (NSCLC) is characterized by high incidence, mortality, and poor patient prognosis, with chemotherapy resistance being a common challenge. This research intends to identify key molecules involved in NSCLC and elucidate the regulatory role of the LINC01605/miR‐7111‐5p/ELK1 axis in chemotherapy resistance. LINC01605 and
Fang Zhang, Zhi‐Liang Yang, Tian‐Tian Qin, Guo‐Jun Zhang, Xiang Li   +4 more
wiley   +1 more source

Mechanisms of transcriptional regulation of CCR5, which is the co-receptor for R5-tropic HIV and is also involved in other disease processes. [PDF]

Biochem Soc Trans
Wang L, Akisa SV, Sutton R.
europepmc   +1 more source

Underground Lag: Fungal Community and Edaphic Legacies After Disturbance

Land Degradation &Development, EarlyView.
ABSTRACT Páramos are neotropical mountain ecosystems that regulate water and store large amounts of carbon, but are increasingly degraded by agriculture and grazing. Although native vegetation often recolonizes after abandonment, belowground recovery remains poorly understood.
Wilmer Dajhan Navarrete‐López, Arantzazu Molins, María Elena Solarte, Camila Enriquez‐Paz, Joshua Borràs, Josefina Bota, Elena Baraza   +6 more
wiley   +1 more source

JAK/STAT-mediated regulation of PD-L1 expression in breast cancer: Molecular mechanisms and implications for immunotherapy. [PDF]

iScience
Sang H, Zhao X.
europepmc   +1 more source