Results 61 to 70 of about 254,908 (357)
The pharmacogenomics of statins
Pharmacological Research, 2014 The statin class of cholesterol-lowering drugs have been used for decades to successfully lower plasma cholesterol concentrations and cardiovascular risk. Adverse effects of statins are generally considered mild, but increase with age of patients and polypharmacy.
Ingrid C, Gelissen, Andrew J, McLachlan
openaire +2 more sources
Arthritis Care &Research, EarlyView.Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada +7 more
wiley +1 more source
Secondary prevention of coronary heart disease in older patients after the national service framework: population based study [PDF]
, 2006 Objective To examine the extent of uptake of medication for secondary prevention of coronary heart disease in older British men and women before (1998-2001) and after (2003) the implementation of the national service framework.Design Two population based,
Morris, RW +15 more
core +1 more source
The Use of Statins in Primary Prevention of Cardiovascular Disease: Benefits versus Risks
, 2022 Background: Cardiovascular disease (CVD) remains a major global health issue. The use of statins in people with a history of CVD is generally well established, however, debate remains about their use for primary prevention in people without CVD.
Irawati, Sylvi +4 more
core +2 more sources
Methodist DeBakey Cardiovascular Journal, 2019 The discovery of statins (3-hydroxy-3-methylglutaryl CoA reductase inhibitors) is a consequence of the highly targeted, arduous search for naturally occurring compounds that inhibit cholesterol biosynthesis. An enormous amount of basic scientific, genetic, and clinical research substantiated the role of lipoprotein-derived cholesterol in atherogenesis.
Peter P, Toth, Maciej, Banach
openaire +2 more sources
Arthritis Care &Research, EarlyView.Objective Hydroxychloroquine (HCQ) is the cornerstone of systemic lupus erythematosus (SLE) management with benefits extending beyond SLE control, including protection against atherosclerotic cardiovascular disease (ASCVD). Although HCQ blood levels reflect recent exposure and long‐term intake reflects medication adherence, the impact of longitudinal ...
Shivani Garg +5 more
wiley +1 more source
S44 | STATINS | Statins Collection from Public Resources
, 2019 <p>This is the collection associated with list S44 STATINS on the NORMAN Suspect List Exchange.</p> <p><a href="https://www.norman-network.com/?q=suspect-list-exchange">https://www.norman-network.com/?q=suspect-list-exchange< ...
Schymanski, Emma +3 more
core +1 more source
Do statins offer therapeutic potential in inflammatory arthritis? [PDF]
, 2004 No abstract ...
McInnes, I.B., McCarey, D., Sattar, N.
core +1 more source
Arthritis Care &Research, EarlyView.Objective Systemic sclerosis (SSc) is characterized by cardiovascular risk excess not fully explained by traditional factors. Whether the severity of microvascular damage correlates with structural subclinical atherosclerosis remains unclear. We investigated the relationship between nailfold videocapillaroscopy (NVC) abnormalities and carotid ...
Eugenio Capparelli +13 more
wiley +1 more source
Statins: antimicrobial resistance breakers or makers? [PDF]
PeerJ, 2017 Introduction The repurposing of non-antibiotic drugs as adjuvant antibiotics may help break antimicrobial resistance (AMR). Statins are commonly prescribed worldwide to lower cholesterol.
Humphrey H.T. Ko +3 more
doaj +2 more sources