Results 41 to 50 of about 25,920 (226)
Staurosporine stimulates phospholipase D activation in human polymorphonuclear leukocytes [PDF]
, 1993 Treatment of 1-O-[3H]alkyl-2-acyl-phosphatidylcholine-prelabeled human polymorphonuclear leukocytes (PMNs) with Staurosporine (50 nM to 1 μM) induced a time- and concentration-dependent generation of tritiated phosphatidic acid (PA), reaching ...
Périanin, Axel +9 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2022 In a variety of physiological and pathophysiological conditions, cells are exposed to acidic environments. Severe synovial fluid acidification also occurs in a progressive state of osteoarthritis (OA) affecting articular chondrocytes.
Michael Kittl +16 more
doaj +1 more source
Angewandte Chemie, EarlyView.Re‐envisioning the Ligandable Proteome: Reactive Metallo‐Scaffolds (r‐mS) combine non‐covalent protein engagement by a metallo‐scaffold with covalent cysteine capture through a tethered chloroacetamide warhead. Chemoproteomic profiling reveals unique enzyme engagement including ligases, kinases and methyltransferases, highlighting opportunities for ...
Jessica E. Waters +15 more
wiley +2 more sources
Staurosporine blocks evoked release of FM1-43 but not acetylcholine from frog motor nerve terminals [PDF]
, 1995 The protein kinase inhibitor staurosporine inhibited, and often abolished, activity-dependent destaining of frog motor nerve terminals that had been preloaded with the fluorescent dye FM1-43.
WJ Betz, AW Henkel
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Herba Polonica, 2021 Flavonoids are widely distributed in the wild. They constitute a large group of compounds that have a beneficial effect on the human body. Apigenin and kaempferol, which belong to the flavone subgroup, have, inter alia, an antitumor effect. The influence
Kosiedowska Magdalena +4 more
doaj +1 more source
Staurosporine-producing Streptomyces sp. strain 11 × 1 cell-free culture filtrates control diseases caused by the oomycete plant pathogens Pythium myriotylum and Phytophthora sojae [PDF]
Oomycetes are devastating soil-borne plant pathogens, and cause numerous losses on diverse crops worldwide. In this study, our aim was to identify actinomycetes with antimicrobial activity towards oomycetes from the rhizosphere of soybean.
Lihui Wei (511898) +14 more
core +1 more source
Staurosporine, a protein kinase inhibitor, activates K-Cl cotransport in LK sheep erythrocytes [PDF]
, 1994 K-Cl cotransport can participate in volume regulation in a number of cell types. Swelling activation of K-Cl cotransport in sheep erythrocytes proceeds by a two-step process, A<-->B<-->C (Dunham et al., J. Gen. Physiol.
P. B. Dunham, I. Bize
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Anti-Parasitic Compounds from Streptomyces sp. Strains Isolated from Mediterranean Sponges
Marine Drugs, 2010 Actinomycetes are prolific producers of pharmacologically important compounds accounting for about 70% of the naturally derived antibiotics that are currently in clinical use. In this study, we report on the isolation of Streptomyces sp.
Heidrun Moll +5 more
doaj +1 more source
Herba Polonica, 2021 Introduction: There are many scientific reports on the beneficial effects of epigallocatechin gallate and resveratrol on the human body, e.g. antioxidant properties, a protective effect on the circulatory system and reduction of inflammation.
Burczak Arkadiusz +3 more
doaj +1 more source
Total Synthesis of (+)-RK-286c, (+)-MLR-52, (+)-Staurosporine, and (+)-K252a [PDF]
, 2016 Total Synthesis of (+)-RK-286c, (+)-MLR-52, (+)-Staurosporine, and ...
Brian M. Stoltz (1297560) +2 more
core +1 more source