Results 121 to 130 of about 2,874 (264)

The Stellar Initial Mass Function and Beyond

open access: yes, 2002
Presented at the IAOC Workshop on "Galactic Star Formation Across the Stellar Mass Spectrum", La Serena, Chile, March 2002; published in the ASP Conference Series, edited by J. M. De Buizer and N. S. van der Bliek.
openaire   +2 more sources

On the Signature of Black Holes on the Quenched Stellar Mass Function

open access: yesThe Astrophysical Journal
Abstract As star-forming galaxies approach or exceed a stellar mass of around 1011 M ⊙, they are increasingly likely to be quenched in a process generically called mass quenching. Central galaxies, which are quenched via mass rather than environmental quenching, therefore accumulate in a peak around ...
Antonio J. Porras-Valverde   +1 more
openaire   +3 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Calibrating Eruptive Mass Loss in Red Supergiants with Local Group Data

open access: yesThe Astrophysical Journal
We calibrate a physically motivated, super-Eddington eruptive mass-loss prescription for red supergiants (RSGs) using Local Group stellar populations.
Shelley J. Cheng   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Rotation curves velocities obtained by warm low-density plasma simulating dark halos and “dark matter”

open access: yesAIP Advances
The free electron model with Boltzmann statistics for spherical low-density plasmas is developed further, with asymptotic relations obtaining the density of electrons, mass densities, and the potentials of such plasmas.
Y. Ben-Aryeh
doaj   +1 more source

Constraining the Initial Mass Function via Stellar Transients

open access: yesUniverse
The stellar initial mass function (IMF) represents a fundamental quantity in astrophysics and cosmology describing the mass distribution of stars from low mass all the way up to massive and very massive stars. It is intimately linked to a wide variety of topics, including stellar and binary evolution, galaxy evolution, chemical enrichment, and ...
Francesco Gabrielli   +6 more
openaire   +3 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

The stellar mass function of Praesepe

open access: yesThe Astrophysical Journal, 1995
D. M. Williams   +2 more
openaire   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

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