Results 121 to 130 of about 111,751 (340)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The coevolution of the velocity and mass functions of galaxies and dark haloes

, 2010
We employ a bias-corrected abundance matching technique to investigate the coevolution of the LCDM dark halo mass function (HMF), the observationally derived velocity dispersion and stellar mass functions (VDF, SMF) of galaxies between z=1 and 0.
Abadi, Auger, Battaglia, Battaglia, Behroozi, Bell, Bell, Bernardi, Bezanson, Blumenthal, Bolton, Boylan-Kolchin, Brown, Bryan, Bullock, Bundy, Cappellari, Cattaneo, Cenarro, Chae, Chae, Chartas, Choi, Cimatti, Cimatti, Conroy, Conroy, Conselice, Cool, Courteau, de Ravel, Desroches, di Serego Alighieri, Dunkley, Dutton, Faber, Feldmann, Ferrarese, Fontana, Fontanot, Gao, Gavazzi, Gnedin, Grillo, Guo, Ho, Hopkins, Hopkins, Hopkins, Hyde, Ilbert, Jenkins, Kazantzidis, Klypin, Klypin, Kochanek, Koopmans, Kravtsov, Kyu-Hyun Chae, Lacey, Li, Loeb, Lokas, Longhetti, Lukić, Macciò, Marchesini, Masjedi, Matsuoka, Moster, Nakajima, Navarro, Navarro, Newman, Nipoti, Oguri, Pizagno, Pizzella, Pozzetti, Press, Pérez-González, Reed, Rudd, Saha, Scarlata, Seigar, Shankar, Sheth, Sheth, Sheth, Springel, Stringer, Tasitsiomi, Tinker, Tissera, Tonry, Treu, Trujillo, Vale, van der Wel, van der Wel, van Dokkum, van Dokkum, Wake, Warren, Wechsler, White, White, Winn, Xue   +109 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Constraints on the Galaxy Formation Models during the Epoch of Reionization with High-redshift Observations

The Astrophysical Journal
We use high-resolution N -body dark matter simulations and L-G alaxies semianalytical galaxy formation models to explore the high- z galaxy properties and estimate the budget of ionizing photons.
Qing-Bo Ma, Xiao-Rong Chen, Ming Li, Qi Guo, Benedetta Ciardi, Anshuman Acharya, Xin Wang   +6 more
doaj   +1 more source

A Statistical Semi-Empirical Model: Satellite galaxies in Groups and Clusters

, 2018
We present STEEL a STatistical sEmi-Empirical modeL designed to probe the distribution of satellite galaxies in groups and clusters. Our fast statistical methodology relies on tracing the abundances of central and satellite haloes via their mass ...
Bernardi, M., Grylls, P. J., Shankar, F., Zanisi, L.   +3 more
core   +1 more source

Faint Stars in a Faint Galaxy. II. The Low-mass Stellar Initial Mass Function of the Boötes I Ultrafaint Dwarf Spheroidal Galaxy [PDF]

, 2022
Carrie Filion, I. Platais, Rosemary F. Ġ. Wyse, V. Kozhurina-Platais   +3 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Surprisingly Similar: The Mass Function of Gaia Neutron Stars and Firstborn Double Neutron Stars

The Astrophysical Journal Letters
The mass distribution of neutron stars (NSs) encodes information about their formation and binary evolution. We compare the masses of two distinct populations: (I) the recently identified Gaia NSs in wide orbits with solar-like companions and (II) the ...
Aryanna Schiebelbein-Zwack, L. A. C. van Son, Maya Fishbach, Will M. Farr   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Linking haloes to galaxies: how many halo properties are needed?

, 2011
Recent studies emphasize that an empirical relation between the stellar mass of galaxies and the mass of their host dark matter subhaloes can predict the clustering of galaxies and its evolution with cosmic time.
Baldry, Behroozi, Berlind, Bernardi, Binney, Bode, Borch, Bundy, Cheng Li, Conroy, Conroy, Conroy, Cox, Croton, Croton, Davis, De Lucia, Drory, Drory, Eyal Neistein, Font, Fontana, Gao, Gao, Guo, Harker, Kauffmann, Khochfar, Kravtsov, Li, Li, Macciò, Mandelbaum, Marchesini, McCarthy, Michael Boylan-Kolchin, Mihos, Moster, Neistein, Panter, Pérez-González, Sawala, Shankar, Simone M. Weinmann, Somerville, Springel, Springel, Tinker, Vale, van den, Wang, Wechsler, Weinmann, Weinmann, Yang, Zehavi   +55 more
core   +1 more source