Results 101 to 110 of about 985,930 (333)
The Astrophysical JournalIn interstellar environments, gas-phase polycyclic aromatic hydrocarbon (PAH) predominantly involves (photo)fragmentation, hydrogenation, and oxidation chemical routes, which lead to the formation of complex organic species.
Xiaoyi Hu +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
Possible role of human ribonuclease dicer in the regulation of R loops
FEBS Open Bio, EarlyView.R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel +3 more
wiley +1 more source
The Absolute Age of Milky Way Globular Clusters
The Astrophysical JournalGlobular clusters (GCs) provide statistically significant coeval populations of stars spanning various evolutionary stages, allowing robust constraints on stellar evolution model parameters and ages.
Jiaqi (Martin) Ying +4 more
doaj +1 more source
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
FEBS Open Bio, EarlyView.Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji +3 more
wiley +1 more source
Asteroseismic Structure Inversions of Main-sequence Solar-like Oscillators with Convective Cores
The Astrophysical JournalAsteroseismic inferences of main-sequence solar-like oscillators often rely on best-fit models. However, these models cannot fully reproduce the observed mode frequencies, suggesting that the internal structure of the model does not fully match that of ...
Lynn Buchele +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley +1 more source
High Time Resolution Photometry of Red Dwarf Flare Stars III. The Most Rapid and Faintest Observed Stellar Flares; their Physics and Statistics [PDF]
, 1989 G. M. Beskin +5 more
openalex +1 more source