Results 101 to 110 of about 3,799 (315)

VLT/FLAMES-ARGUS observations of stellar wind-ISM cloud interactions in NGC 6357★ [PDF]

, 2009
M. S. Westmoquette, Jonathan D. Slavin, L. J. Smith, J. S. Gallagher   +3 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

MINDS. JWST-MIRI Observations of a Spatially Resolved Atomic Jet and Polychromatic Molecular Wind toward SY Cha

The Astrophysical Journal
The removal of angular momentum from protostellar systems drives accretion onto the central star and may drive the dispersal of the protoplanetary disk. Winds and jets can contribute to removing angular momentum from the disk, though the dominant process
Kamber R. Schwarz, Matthias Samland, Göran Olofsson, Thomas Henning, Andrew Sellek, Manuel Güdel, Benoît Tabone, Inga Kamp, Pierre-Olivier Lagage, Ewine F. van Dishoeck, Alessio Caratti o Garatti, Adrian M. Glauser, Tom P. Ray, Aditya M. Arabhavi, Valentin Christiaens, R. Franceschi, Danny Gasman, Sierra L. Grant, Jayatee Kanwar, Till Kaeufer, Nicolas T. Kurtovic, Giulia Perotti, Milou Temmink, Marissa Vlasblom   +23 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Investigating Protostellar Accretion-driven Outflows across the Mass Spectrum: JWST NIRSpec Integral Field Unit 3–5 μm Spectral Mapping of Five Young Protostars

The Astrophysical Journal
Investigating Protostellar Accretion is a Cycle 1 JWST program using the NIRSpec+MIRI integral field units to obtain 2.9–28 μ m spectral cubes of five young protostars with luminosities of 0.2–10,000 L _⊙ in their primary accretion phase.
Samuel A. Federman, S. Thomas Megeath, Adam E. Rubinstein, Robert Gutermuth, Mayank Narang, Himanshu Tyagi, P. Manoj, Guillem Anglada, Prabhani Atnagulov, Henrik Beuther, Tyler L. Bourke, Nashanty Brunken, Alessio Caratti o Garatti, Neal J. Evans II, William J. Fischer, Elise Furlan, Joel D. Green, Nolan Habel, Lee Hartmann, Nicole Karnath, Pamela Klaassen, Hendrik Linz, Leslie W. Looney, Mayra Osorio, James Muzerolle Page, Pooneh Nazari, Riwaj Pokhrel, Rohan Rahatgaonkar, Will R. M. Rocha, Patrick Sheehan, Katerina Slavicinska, Thomas Stanke, Amelia M. Stutz, John J. Tobin, Lukasz Tychoniec, Ewine F. Van Dishoeck, Dan M. Watson, Scott Wolk, Yao-Lun Yang   +38 more
doaj   +1 more source

GLOBAL SIMULATIONS OF THE INTERACTION OF MICROQUASAR JETS WITH A STELLAR WIND IN HIGH-MASS X-RAY BINARIES [PDF]

, 2015
Doosoo Yoon, Sebastian Heinz
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Stellar-wind-blown Bubbles as Environments for Late-time Rebrightening of Gamma-ray Burst Afterglows

The Astrophysical Journal Letters
We present multiwavelength afterglow fitting results for three events that exhibit late afterglow rebrightening behavior: EP240414a ( z = 0.401), GRB 240529A ( z = 2.695), and GRB 240218A ( z = 6.782), which span a broad range of redshifts, from the ...
Jia Ren, Xiao-Yan Li, Yun Wang, Lu-Lu Zhang, Da-Ming Wei, Zi-Gao Dai, Zhi-Ping Jin, Da-Bin Lin   +7 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Obscuring Supersoft X-ray Sources in Stellar Winds [PDF]

, 2011
Mikkel Nielsen, C. Dominik, G. Nelemans
openalex   +1 more source