Results 111 to 120 of about 1,187 (260)

MINDS. JWST-MIRI Observations of a Spatially Resolved Atomic Jet and Polychromatic Molecular Wind toward SY Cha

The Astrophysical Journal
The removal of angular momentum from protostellar systems drives accretion onto the central star and may drive the dispersal of the protoplanetary disk. Winds and jets can contribute to removing angular momentum from the disk, though the dominant process
Kamber R. Schwarz, Matthias Samland, Göran Olofsson, Thomas Henning, Andrew Sellek, Manuel Güdel, Benoît Tabone, Inga Kamp, Pierre-Olivier Lagage, Ewine F. van Dishoeck, Alessio Caratti o Garatti, Adrian M. Glauser, Tom P. Ray, Aditya M. Arabhavi, Valentin Christiaens, R. Franceschi, Danny Gasman, Sierra L. Grant, Jayatee Kanwar, Till Kaeufer, Nicolas T. Kurtovic, Giulia Perotti, Milou Temmink, Marissa Vlasblom   +23 more
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Investigating Protostellar Accretion-driven Outflows across the Mass Spectrum: JWST NIRSpec Integral Field Unit 3–5 μm Spectral Mapping of Five Young Protostars

The Astrophysical Journal
Investigating Protostellar Accretion is a Cycle 1 JWST program using the NIRSpec+MIRI integral field units to obtain 2.9–28 μ m spectral cubes of five young protostars with luminosities of 0.2–10,000 L _⊙ in their primary accretion phase.
Samuel A. Federman, S. Thomas Megeath, Adam E. Rubinstein, Robert Gutermuth, Mayank Narang, Himanshu Tyagi, P. Manoj, Guillem Anglada, Prabhani Atnagulov, Henrik Beuther, Tyler L. Bourke, Nashanty Brunken, Alessio Caratti o Garatti, Neal J. Evans II, William J. Fischer, Elise Furlan, Joel D. Green, Nolan Habel, Lee Hartmann, Nicole Karnath, Pamela Klaassen, Hendrik Linz, Leslie W. Looney, Mayra Osorio, James Muzerolle Page, Pooneh Nazari, Riwaj Pokhrel, Rohan Rahatgaonkar, Will R. M. Rocha, Patrick Sheehan, Katerina Slavicinska, Thomas Stanke, Amelia M. Stutz, John J. Tobin, Lukasz Tychoniec, Ewine F. Van Dishoeck, Dan M. Watson, Scott Wolk, Yao-Lun Yang   +38 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Stellar-wind-blown Bubbles as Environments for Late-time Rebrightening of Gamma-ray Burst Afterglows

The Astrophysical Journal Letters
We present multiwavelength afterglow fitting results for three events that exhibit late afterglow rebrightening behavior: EP240414a ( z = 0.401), GRB 240529A ( z = 2.695), and GRB 240218A ( z = 6.782), which span a broad range of redshifts, from the ...
Jia Ren, Xiao-Yan Li, Yun Wang, Lu-Lu Zhang, Da-Ming Wei, Zi-Gao Dai, Zhi-Ping Jin, Da-Bin Lin   +7 more
doaj   +1 more source

Stellar Winds

The Astrophysical Journal, 1970
Peter Goldreich, William H. Julian
openaire   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Measuring the magnetic fields in the chromospheres of low-mass stars [PDF]

Nat Commun
Cang T, Petit P, Donati J, Tian H, Fu J, Li H, Bellotti S, Hu X, Ma X, Ariste AL, Xing K, Morin J, Lu H, Zong W.   +13 more
europepmc   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source