Results 111 to 120 of about 3,799 (315)

Role of Longitudinal Waves in Alfvén-wave-driven Solar/Stellar Wind [PDF]

open access: hybrid, 2021
Kimihiko Shimizu   +2 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

A Study of Emission Lines in Carbon Stars

open access: yesThe Astrophysical Journal
Carbon stars are chemically peculiar stars with high carbon abundance, showing strong carbon molecule bands and rare emission lines in their spectra. This paper explores the stellar activity of carbon stars by identifying emission line features in their ...
Lichan Zhou   +5 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

PROJECT-J: The Shocking H2 Outflow from HH 46

open access: yesThe Astrophysical Journal
We analyze the H _2 emission observed in the HH 46 Class I system as part of PROtostellar JEts Cradle Tested with JWST (PROJECT-J), to investigate the origin and excitation of the warm molecular outflow. We used NIRSpec and MIRI spectral maps (1.6–27.9 μ
Maria Gabriela Navarro   +16 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

An Extremely Young Protostellar Core, MMS 1/OMC-3: Episodic Mass Ejection History Traced by the Micro SiO Jet

open access: yesThe Astrophysical Journal
We present ∼0.″2 (∼80 au) resolution observations of the CO(2–1) and SiO(5–4) lines made with the Atacama large millimeter/submillimeter array toward an extremely young intermediate-mass protostellar source ( t _dyn < 1000 yr), MMS 1 located in the Orion
Satoko Takahashi   +13 more
doaj   +1 more source

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