Results 121 to 130 of about 1,100,727 (344)

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Stellar winds driven by multi-line scattering [PDF]

, 1983
This paper presents a model of a radiation-driven stellar wind with overlapping spectral lines. It is based on the Castor, Abbott, and Klein (CAK) theory.
Friend, D. B.
core   +1 more source

Accretion and Recovery in Giant Eruptions of Massive Stars

The Astrophysical Journal
Giant eruptions are episodic high-rate mass-loss events that massive stars experience in the late-stage of their evolution before exploding as a core-collapse supernova.
Bhawna Mukhija, Amit Kashi
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Molecular Bubble and Outflow in S Mon Revealed by Multiband Data Sets

The Astrophysical Journal
We identify a molecular bubble, and study the star formation and its feedback in the S Mon region, using multiple molecular lines, young stellar objects (YSOs), and infrared data.
Dejian Liu, Ye Xu, YingJie Li, Zehao Lin, Chaojie Hao, WenJin Yang, Jingjing Li, Xinrong Liu, Yiwei Dong, Shuaibo Bian, Deyun Kong   +10 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Atmospheric Heating and Wind Acceleration: Results for Cool Evolved Stars based on Proposed Processes

, 2014
A chromosphere is a universal attribute of stars of spectral type later than ~F5. Evolved (K and M) giants and supergiants (including the zeta Aurigae binaries) show extended and highly turbulent chromospheres, which develop into slow massive winds.
A. Brown, A. Chiavassa, A. Lobel, A. Lébre, A. Skumanich, A.D. McMurry, A.K. Dupree, B. Buchholz, B. Freytag, B. Pontieu De, B. Pontieu De, B. Pontieu De, B.E. Wood, C.-H. An, C.J. Schrijver, C.J. Schrijver, D. Fawzy, D. Rabin, D. Reimers, D.E. Osterbrock, D.F. Gray, D.J. Mullan, F.P. Pijpers, G.A. Gary, G.M. Harper, G.M. Harper, G.M. Harper, H. Alfvén, H. Peter, H. Peter, I. Pagano, J. Martínez-Sykora, J. Tu, J.A. Eaton, J.A. Eaton, J.D. Jackson, J.E. Leake, J.E. Leake, J.E. Leake, J.E. Leake, J.E. Vernazza, J.E. Vernazza, J.G. Doyle, J.G. Doyle, J.H. Piddington, J.L. Linsky, J.L. Linsky, J.M. Davila, J.M. Fontenla, J.M. Fontenla, J.V. Hollweg, J.V. Hollweg, K. Eriksson, K. Ohnaka, K.-P. Schröder, K.B. MacGregor, K.G. Carpenter, K.G. Carpenter, K.G. Carpenter, K.G. Carpenter, K.G. Strassmeier, L. Hartmann, L. Hartmann, L. Ofman, L. Ofman, L.S. Anderson, M. Auriére, M. Cuntz, M. Cuntz, M. Cuntz, M. Cuntz, M. Cuntz, M. Cuntz, M. Heinemann, M. Mathioudakis, M. Mitchner, M. Velli, M.C.M. Cheung, M.I. Pérez Martínez, M.L. Goodman, M.L. Goodman, M.L. Goodman, M.L. Khodachenko, M.R. Barkhudarov, M.S. Ruderman, N. Guerreiro, P. Charbonneau, P. Petit, P. Song, P. Ulmschneider, P. Ulmschneider, P.G. Judge, P.G. Judge, P.G. Judge, P.G. Judge, P.K. Shukla, R. Grappin, R. Lundin, R. Rosner, R. Rosner, R. Soler, R.A. Kopp, R.D. Robinson, R.G.M. Rutten, R.J. Morton, R.J. Morton, R.K. Konstantinova-Antova, R.K. Konstantinova-Antova, R.W Noyes, S. Tomczyk, S.B.F. Dorch, S.I. Braginskii, S.R. Cranmer, S.R. Cranmer, S.R. Cranmer, S.R. Cranmer, T. Simon, T. Tsuji, T.D. Arber, T.E. Holzer, T.K. Suzuki, T.K. Suzuki, T.K. Suzuki, T.R. Ayres, T.R. Ayres, T.R. Ayres, T.R. Ayres, U. Narain, U. Narain, U. Torkelsson, V. Hansteen, V. Krasnoselskikh, V.H. Hansteen, V.S. Airapetian, V.S. Airapetian, V.S. Airapetian, W.C. Danchi, W.H. Matthaeus, Y.-T. Lau, Z.E. Musielak   +139 more
core   +1 more source

The Milky Way Project MOBStIRS: Parameterizing Infrared Stellar-wind Bow Shock Morphologies with Citizen Science

The Astronomical Journal
Mass-loss influences stellar evolution, especially for massive stars with strong winds. Stellar wind bow shock nebulae driven by Galactic OB stars can be used to measure mass-loss rates ( $\dot{M}$ ).
Angelica S. Whisnant, Matthew S. Povich, Nikhil Patten, Henry A. Kobulnicky   +3 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

The interface between the stellar wind and interstellar medium around R Cassiopeiae revealed by far-infrared imaging [PDF]

, 2009
T. Ueta, R. E. Stencel, I. Yamamura, K. M. Geise, A. Karska, H. Izumiura, Y. Nakada, M. Matsuura, Y. Ita, T. Tanabe, Fukushi H, N. Matsunaga, H. Mito, A. K. Speck, T. Ueta, R. E. Stencel, I. Yamamura, K. M. Geise, A. Karska, H. Izumiura, Y. Nakada, M. Matsuura, Y. Ita, T. Tanabe, Fukushi H, N. Matsunaga, H. Mito, A. K. Speck   +27 more
openalex   +1 more source