Results 21 to 30 of about 1,492,484 (317)

Processing Adipose Tissue Samples in a GMP Environment Standardizes the Use of SVF in Cell Therapy Treatments: Data on 302 Patients

open access: yesBiomedicines, 2023
Stromal vascular fraction (SVF) cells, together with adipose-derived mesenchymal stem cells, are becoming the tool of choice for many clinical applications.
Martina Cremona   +5 more
doaj   +1 more source

Stem cells, cancer, and cancer stem cells [PDF]

open access: yesNature, 2001
Stem cell biology has come of age. Unequivocal proof that stem cells exist in the haematopoietic system has given way to the prospective isolation of several tissue-specific stem and progenitor cells, the initial delineation of their properties and expressed genetic programmes, and the beginnings of their utility in regenerative medicine.
Reya, T.   +3 more
openaire   +3 more sources

Treatment of shoulder osteoarthritis and rotator cuff tears with bone marrow concentrate and whole bone marrow injections

open access: yesCogent Medicine, 2019
Background: Human bone marrow has shown promise as a minimally invasive approach in treating a variety of musculoskeletal conditions due to the presence of stem cells, platelets, and growth factors in solution.
Marc Darrow   +4 more
doaj   +1 more source

Stem cells supporting other stem cells [PDF]

open access: yesFrontiers in Genetics, 2013
Adult stem cell therapies are increasingly prevalent for the treatment of damaged or diseased tissues, but most of the improvements observed to date are attributed to the ability of stem cells to produce paracrine factors that have a trophic effect on existing tissue cells, improving their functional capacity.
openaire   +3 more sources

PTEN, Stem Cells, and Cancer Stem Cells [PDF]

open access: yesJournal of Biological Chemistry, 2009
Like normal stem cells, "cancer stem cells" have the capacity for indefinite proliferation and generation of new cancerous tissues through self-renewal and differentiation. Among the major intracellular signaling pathways, WNT, SHH, and NOTCH are known to be important in regulating normal stem cell activities, and their alterations are associated with ...
Reginald, Hill, Hong, Wu
openaire   +2 more sources

Treatment of unresolved lower back pain with platelet-rich plasma injections

open access: yesCogent Medicine, 2019
Background: Platelet-Rich Plasma (PRP) is a non-invasive modality that has been used to treat musculoskeletal conditions for the past two decades. Based on our research, there were no publications that studied the effect of PRP on unresloved lower back ...
Marc Darrow   +4 more
doaj   +1 more source

Prostate Stem Cells and Cancer Stem Cells [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2018
Stem/progenitor cells play central roles in processes of organogenesis and tissue maintenance, whereas cancer stem cells (CSCs) are thought to drive tumor malignancy. Here, we review recent progress in the identification and analysis of normal prostate stem/progenitor cells as well as putative CSCs in both genetically engineered mouse models as well as
Jia J, Li, Michael M, Shen
openaire   +2 more sources

Nitric oxide has contrasting age-dependent effects on the functionality of murine hematopoietic stem cells

open access: yesStem Cell Research & Therapy, 2016
Background The success of hematopoietic stem cell (HSC) transplantation is dependent on the quality of the donor HSCs. Some sources of HSCs display reduced engraftment efficiency either because of inadequate number (e.g., fetal liver and cord blood), or ...
Sapana Jalnapurkar   +4 more
doaj   +1 more source

Integrating deep learning and unbiased automated high-content screening to identify complex disease signatures in human fibroblasts

open access: yesNature Communications, 2022
By coupling robotic cell culture systems with artificial intelligence–powered image analysis, Schiff et al. identify previously unseen characteristics of Parkinson’s disease in patient skin cells that distinguish them from healthy controls.
Lauren Schiff   +42 more
doaj   +1 more source

MicroRNAs as Important Regulators Mediate the Multiple Differentiation of Mesenchymal Stromal Cells

open access: yesFrontiers in Cell and Developmental Biology, 2021
MicroRNAs (miRNAs) are endogenous short non-encoding RNAs which play a critical role on the output of the proteins, and influence multiple biological characteristics of the cells and physiological processes in the body.
Chao Yang   +5 more
doaj   +1 more source

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