Results 21 to 30 of about 2,387,298 (366)
Cells, 2023 Liver transplantation is currently the only curative therapy for patients with acute or chronic liver failure. However, a dramatic gap between the number of available liver grafts and the number of patients on the transplantation waiting list emphasizes ...
Burak Toprakhisar +2 more
doaj +1 more source
The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration. [PDF]
, 2019 Metabolic reprogramming is an active regulator of stem cell fate choices, and successful stem cell differentiation in different compartments requires the induction of oxidative phosphorylation.
Cunningham, Thomas J +9 more
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Stem Cells and Cancer Stem Cells [PDF]
, 2011 The different organs in human organism are constituted by tissues with mature and specialized cells and its specific stem cells. Stem cells represent only a minuscule fraction of cells that constitute each tissue but they are the only cells with self-renewal capacity. The organ-specific stem cells have specific properties that maintain tissue integrity
Alfredo Ribeiro-Silva +2 more
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Differential sensitivity of Glioma stem cells to Aurora kinase A inhibitors: implications for stem cell mitosis and centrosome dynamics [PDF]
, 2014 Glioma stem-cell-like cells are considered to be responsible for treatment resistance and tumour recurrence following chemo-radiation in glioblastoma patients, but specific targets by which to kill the cancer stem cell population remain elusive.
Chalmers, Anthony J. +3 more
core +3 more sources
Cell and Tissue Research, 2011 Glioblastomas are highly malignant primary brain tumors with one of the worst survival rates among all human cancers. With a more profound understanding of the cellular and molecular mechanisms of tumor initiation and acquired resistance to conventional radio- and chemotherapy, novel therapeutic targets might be discovered to optimize therapeutic ...
Tabatabai, G, Weller, M
openaire +4 more sources
Stem Cells International, 2022 Bone marrow aspirate concentrate (BMC) is commonly used as a therapeutic agent to resolve orthopedic injuries, using its unique cellularity to reduce inflammation and prime the region for repair.
Ryan C. Dregalla +3 more
doaj +1 more source
Stem cells: the intestinal stem cell as a paradigm [PDF]
Carcinogenesis, 2000 Stem cell research provides a foundation for therapeutic advancement in oncology, clinical genetics and a diverse array of degenerative disorders. For example, the elucidation of pathways governing proliferative regulation and differentiation within cellular systems will result in medical strategies aimed at the root cause of cancer.
Andrew G Renehan +2 more
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Stem cell population asymmetry can reduce rate of replicative aging [PDF]
Journal of Theoretical Biology 331 (2013) 19-27, 2012 Cycling tissues such as the intestinal epithelium, germ line, and hair follicles, require a constant flux of differentiated cells. These tissues are maintained by a population of stem cells, which generate differentiated progenies and self-renew. Asymmetric division of each stem cell into one stem cell and one differentiated cell can accomplish both ...
arxiv +1 more source
Multipotency of Adult Hippocampal NSCs In Vivo Is Restricted by Drosha/NFIB [PDF]
, 2016 Adult neural stem cells (NSCs) are defined by their inherent capacity to self-renew and give rise to neurons, astrocytes, and oligodendrocytes. In vivo, however, hippocampal NSCs do not generate oligodendrocytes for reasons that have remained enigmatic ...
Alice Grison +51 more
core +2 more sources
The Stem Cells and the Cancer Stem Cells [PDF]
Journal of Gynecology and Womens Health, 2019 n ...
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