Results 41 to 50 of about 193,899 (265)

Resistin Regulates Inflammation and Insulin Resistance in Humans via the Endocannabinoid System

Research
Resistin plays an important role in the pathophysiology of obesity-mediated insulin resistance in mice. However, the biology of resistin in humans is quite different from that in rodents. Therefore, the association between resistin and insulin resistance
Han-Mo Yang, Joonoh Kim, Baek-Kyung Kim, Hyun Ju Seo, Ju-Young Kim, Joo-Eun Lee, Jaewon Lee, Jihye You, Sooryeonhwa Jin, Yoo-Wook Kwon, Hyun-Duk Jang, Hyo-Soo Kim   +11 more
doaj   +1 more source

Companion Blood Cells Control Ovarian Stem Cell Niche Microenvironment and Homeostasis

Cell Reports, 2015
The extracellular matrix plays an essential role for stem cell differentiation and niche homeostasis. Yet, the origin and mechanism of assembly of the stem cell niche microenvironment remain poorly characterized.
Véronique Van De Bor, Geordie Zimniak, Lise Papone, Delphine Cerezo, Marilyne Malbouyres, Thomas Juan, Florence Ruggiero, Stéphane Noselli   +7 more
doaj   +1 more source

Niche formation and function in developing tissue: studies from the Drosophila ovary

Cell Communication and Signaling, 2023
Adult stem cells have a unique ability to self-renew and to generate differentiated daughter cells that are required in the body tissues. The identity of adult stem cells is maintained by extrinsic signals from other cell types, known as niche cells ...
Jian Jin, Ting Zhao
doaj   +1 more source

Lack of correlation of stem cell markers in breast cancer stem cells [PDF]

, 2014
BACKGROUND: Various markers are used to identify the unique sub-population of breast cancer cells with stem cell properties. Whether these markers are expressed in all breast cancers, identify the same population of cells, or equate to therapeutic ...
A M Thompson, AM Thompson, C Calabrese, C Ginestier, C Scheel, C Sheridan, CE Eyler, CL Chaffer, CM Fillmore, E Charafe-Jauffret, E Resetkova, EY Tan, F Vaillant, G Farnie, G Kristiansen, G Rappa, H Harrison, H Korkaya, J Stingl, J Zhou, JC Lawson, JM Rosen, K Engelmann, K He, K Murray, M Al-Hajj, M Boylan, M Christgen, M Kok, M Pajic, M V Appleyard, MA Ahmed, ME Prince, MH Wright, MJ Grimshaw, MV Appleyard, O Al-Assar, O Leis, O Moussa, P J Coates, P Kabos, R Nenutil, S Bao, S Liu, SY Kim, SY Park, T Tanei, TM Phillips, WW Hwang-Verslues, Y Liu   +49 more
core   +4 more sources

The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1-CD44 axis. [PDF]

, 2020
The endosteal bone marrow niche and vascular endothelial cells provide sanctuaries for leukemic cells. In murine chronic myeloid leukemia (CML) CD44 on leukemia cells and E-selectin on bone marrow endothelium are essential mediators for the engraftment ...
Aggoune, D., Godavarthy, P., Hayduk, N., Herkt, S., Krause, D., Kumar, R., Lausen, J., Lucas, T., Manavski, Y., Müller, M., Oehler, V., Oellerich, T., Pan, K., Pereira, R., Saussele, S., Voutsinas, J., Weissenberger, E., Wu, Q.   +17 more
core   +2 more sources

Sas-Ptp10D shapes germ-line stem cell niche by facilitating JNK-mediated apoptosis.

PLoS Genetics, 2023
The function of the stem cell system is supported by a stereotypical shape of the niche structure. In Drosophila ovarian germarium, somatic cap cells form a dish-like niche structure that allows only two or three germ-line stem cells (GSCs) reside in the
Kiichiro Taniguchi, Tatsushi Igaki
doaj   +1 more source

Spindle positioning in the stem cell niche [PDF]

, 2012
Stem cells are the source of differentiated cells that constitute tissues and organs. Two fundamental characteristics of stem cells are their abilities to self‐renew stem cell identity and to produce differentiated cells, the balance of which can be ...
Basto, Basto, Bond, Bond, Boyle, Brawley, Burkin, Cabernard, Cairns, Charge, Chen, Chen, Chen, Cheng, Cheng, Cheng, Clayton, Conboy, Conboy, Conboy, Conduit, Cornelison, Crittenden, Crittenden, Crittenden, Decotto, Deng, Falconer, Farkas, Fei, Fuchs, Fuller, Garcia-Mata, Hardy, Hirata, Inaba, Januschke, Kai, Kaltschmidt, Karpowicz, Karpowicz, Kawase, Kiel, Kiger, Knoblich, Knoblich, Kuang, Leatherman, Leatherman, Lechler, Lin, Lopez-Onieva, McGrail, Megraw, Megraw, Megraw, Megraw, Micchelli, Molofsky, Morris, Morrison, Ohlstein, Ohlstein, Pan, Poulson, Quyn, Rando, Rebollo, Rebollo, Riparbelli, Rossi, Roth, Rujano, Rusan, Sangiorgi, Sato, Sato, Schepers, Schulz, Shinin, Shivdasani, Siller, Silva, Smith, Snippert, Song, Song, Sotiropoulou, Spana, Stevens, Suzuki, Szakmary, Tajbakhsh, Tatsumi, Terry, Tulina, Vaizel-Ohayon, Voog, Waghmare, Wallenfang, Wang, Wang, Williams, Xie, Xie, Xie, Yadlapalli, Yamashita, Yamashita, Yamashita, Yamashita   +110 more
core   +1 more source

Vascular signalling mediated by ZWILLE potentiates WUSCHEL function during shoot meristem stem cell development in the Arabidopsis embryo [PDF]

, 2008
Stem cells are maintained in an undifferentiated state by signals from their microenvironment, the stem cell niche. Despite its central role for organogenesis throughout the plant's life, little is known about how niche development is regulated in the ...
Hinze, A., Jurgens, G., Laux, T., Takada, S., Tucker, E., Tucker, M.   +5 more
core   +1 more source

Hypoxic Culture Conditions as a Solution for Mesenchymal Stem Cell Based Regenerative Therapy [PDF]

, 2014
Cell-based regenerative therapies, based on in vitro propagation of stem cells, offer tremendous hope to many individuals suffering from degenerative diseases that were previously deemed untreatable.
Abu Kasim, N. H., Alabsi, A. M., Haque, N., Rahman, M. T.   +3 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source