Results 31 to 40 of about 2,694 (155)

Secreted factors from cultured dental pulp stem cells promoted neurite outgrowth of dorsal root ganglion neurons and ameliorated neural functions in streptozotocin‐induced diabetic mice

Journal of Diabetes Investigation, 2020
Aims/Introduction Transplantation of stem cells promotes axonal regeneration and angiogenesis in a paracrine manner. In the present study, we examined whether the secreted factors in conditioned medium of stem cells from human exfoliated deciduous teeth (
Emiri Miura‐Yura, Shin Tsunekawa, Keiko Naruse, Nobuhisa Nakamura, Mikio Motegi, Hiromi Nakai‐Shimoda, Saeko Asano, Makoto Kato, Yuichiro Yamada, Takako Izumoto‐Akita, Akihito Yamamoto, Tatsuhito Himeno, Masaki Kondo, Yoshiro Kato, Jiro Nakamura, Hideki Kamiya   +15 more
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Dental stem cells: Dentinogenic, osteogenic, and neurogenic differentiation and its clinical cell based therapies

Indian Journal of Dental Research, 2012
Each year approximately 400 billion is spent treating Americans suffering some type of tissue loss or end-stage organ failure. This includes millions of dental and oral craniofacial procedure, ranging from tooth restorations to major reconstruction of ...
Gurlal Singh Brar, Ravi Sher Singh Toor
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Impaired neurite development associated with mitochondrial dysfunction in dopaminergic neurons differentiated from exfoliated deciduous tooth-derived pulp stem cells of children with autism spectrum disorder

Biochemistry and Biophysics Reports, 2018
Autism spectrum disorder (ASD) is a highly heterogeneous neurodevelopmental disorder characterized by impaired social interactions, restrictive interests, and repetitive stereotypic behaviors.
Huong Thi Nguyen Nguyen, Hiroki Kato, Keiji Masuda, Haruyoshi Yamaza, Yuta Hirofuji, Hiroshi Sato, Thanh Thi Mai Pham, Fumiko Takayama, Yasunari Sakai, Shouichi Ohga, Tomoaki Taguchi, Kazuaki Nonaka   +11 more
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Mitochondria Regulate the Differentiation of Stem Cells from Human Exfoliated Deciduous Teeth

Cell Structure and Function, 2017
Stem cells from human exfoliated deciduous teeth (SHED) are isolated from the dental pulp tissue of primary teeth and can differentiate into neuronal cells. Although SHED are a desirable type of stem cells for transplantation therapy and for the study of neurological diseases, a large part of the neuronal differentiation machinery of SHED remains ...
Kato, Hiroki, Thi Mai Pham, Thanh, Yamaza, Haruyoshi, Masuda, Keiji, Hirofuji, Yuta, Han, Xu, Sato, Hiroshi, Taguchi, Tomoaki, Nonaka, Kazuaki   +8 more
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Peripheral Nerve Regeneration by Secretomes of Stem Cells from Human Exfoliated Deciduous Teeth [PDF]

Stem Cells and Development, 2015
Peripheral nerve regeneration across nerve gaps is often suboptimal, with poor functional recovery. Stem cell transplantation-based regenerative therapy is a promising approach for axon regeneration and functional recovery of peripheral nerve injury; however, the mechanisms remain controversial and unclear. Recent studies suggest that transplanted stem
Yukiko, Sugimura-Wakayama, Wataru, Katagiri, Masashi, Osugi, Takamasa, Kawai, Kenichi, Ogata, Kohei, Sakaguchi, Hideharu, Hibi   +6 more
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Establishing methods for isolation of stem cells from human exfoliated deciduous from carious deciduous teeth

Interventional Medicine and Applied Science, 2018
Aim This study aims to establish the isolation method of stem cells from pulp tissue of carious deciduous teeth. Methods The teeth were soaked in 1% povidone–iodine solution for about 1 min followed by washing in PBS with 1% antibiotic–antimycotic thrice.
Zainuri, Masagus, Putri, Ratih Rinendya, Bachtiar, Endang W.   +2 more
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Immunomodulatory Role of Stem Cells from Human Exfoliated Deciduous Teeth on Periodontal Regeneration [PDF]

Tissue Engineering Part A, 2018
Periodontitis is initiated by the infection of periodontal bacteria and subsequent tissue inflammation due to immunoreaction, eventually leading to periodontal apparatus loss. Stem cells from human exfoliated deciduous teeth (SHEDs) have exhibited beneficial characteristics in dental tissue regeneration. However, the immunomodulatory functions of SHEDs
Gao, Xianling, Shen, Zongshan, Guan, Meiliang, Huang, Qiting, Chen, Lingling, Qin, Wei, Ge, Xiaohu, Chen, Haijia, Xiao, Yin, Lin, Zhengmei   +9 more
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Allogeneic stem cells derived from human exfoliated deciduous teeth (SHED) for the management of periapical lesions in permanent teeth: Two case reports of a novel biologic alternative treatment [PDF]

Journal of Dental Research, Dental Clinics, Dental Prospects, 2017
Stem cells are the pluripotent cells that have the capacity to differentiate into other specialized cells. Recently, many experiments have been conducted to study the potentiality of stem cells in the tissue regeneration.
Madu Ghana Shyam Prasad, Juvva Ramakrishna, Duvvi Naveen Babu   +2 more
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Effect of Calcium-enriched Mixture (CEM) cement on increasing mineralization in stem cells from the dental pulps of human exfoliated deciduous teeth [PDF]

Journal of Dental Research, Dental Clinics, Dental Prospects, 2018
Background.Stem cells isolated from human exfoliated deciduous teeth (SHED) are highly capable of proliferation and differentiation into odontogenic, osteogenic, adipose tissue and neural cells.
Rezvan Rafatjou, Iraj Amiri, Atousa Janeshin   +2 more
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Stem Cells from Human Exfoliated Deciduous Teeth – Isolation, Long Term Cultivation and Phenotypical Analysis

Acta Medica, 2010
Aims: Our aims were to isolate stem cells from human exfoliated deciduous teeth (SHED), to cultivate them in vitro and to investigate their basic biological properties, phenotype and to compare our findings with dental pulp stem cells (DPSC) isolated ...
Jakub Suchánek, Benjamín Víšek, Tomáš Soukup, Sally Kamal El-Din Mohamed, Romana Ivančaková, Jaroslav Mokrý, Eman H. A. Aboul-Ezz, A. Omran   +7 more
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