Results 51 to 60 of about 2,694 (155)

Cell Therapy for Periodontal, Soft‐Tissue, and Craniofacial Regeneration

Journal of Periodontal Research, EarlyView.
The clinical translation of mesenchymal stem/stromal cells (MSCs) represents a major advancement in dentistry, especially for periodontal, soft‐tissue, and craniofacial regeneration. However, several challenges remain to be addressed, including the absence of standardised protocols, limited scalability, regulatory hurdles, a lack of well‐controlled ...
Kamal Mustafa, Shuntaro Yamada, Nerea Sanchez, Magdalena Mayol, Cecilie Gjerde, Mariano Sanz   +5 more
wiley   +1 more source

Healing of large periapical lesions following delivery of dental stem cells with an injectable scaffold: New method and three case reports

Indian Journal of Dental Research, 2014
Regenerative endodontics is the creation and delivery of tissues to replace diseased, missing, and traumatized pulp. A call for a paradigm shift and new protocol for the clinical management of these cases has been brought to attention. These regenerative
Vahab Shiehzadeh, Farhad Aghmasheh, Farideh Shiehzadeh, Mohammad Joulae, Emad Kosarieh, Farid Shiehzadeh   +5 more
doaj   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Dose‐dependent effects of photobiomodulation on stem cells from human exfoliated deciduous teeth cultured on polylactic acid films: An in vitro study

Photochemistry and Photobiology, EarlyView.
660‐nm photobiomodulation increased metabolic activity, modulated cell cycle distribution, and increased apparent surface coverage in dental stem cells cultured on polylactic acid films, with 4 J/cm2 producing the most consistent response and a greater G2/M fraction than 1 J/cm2.
Rômulo Augusto de Paiva Macedo, Vladimir Galdino Sabino, Hugo Alexandre Oliveira Rocha, Moacir Franco de Oliveira, Carlos Eduardo Bezerra de Moura, Carlos Augusto Galvão Barboza   +5 more
wiley   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Phenotypic characterizations and comparison of adult dental stem cells with adipose-derived stem cells

International Journal of Preventive Medicine, 2010
Objectives: Mesenchymal stem cells or ′′multipotent stromal cells′′ are heterogeneous cell population with self-renewal and multi-linage differentiation.
Razieh Alipour, Farzaneh Sadeghi, Batool Hashemi-Beni, Sayyed Hamid Zarkesh-Esfahani, Fariba Heydari, Sayyed Behrouz Mousavi, Minoo Adib, Manizheh Narimani, Nafiseh Esmaeili   +8 more
doaj  

Cytotoxicity assessment of polyhydroxybutyrate/chitosan/nano- bioglass nanofiber scaffolds by stem cells from human exfoliated deciduous teeth stem cells from dental pulp of exfoliated deciduous tooth

Dental Research Journal, 2018
Background: The aim of this study was to compare the cytotoxicity and the biocompatibility of three different nanofibers scaffolds after seeding of stem cells harvested from human deciduous dental pulp.
Batool Hashemi-Beni, Maryam Khoroushi, Mohammad Reza Foroughi, Saeed Karbasi, Abbas Ali Khademi   +4 more
doaj   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Stem Cell and EV/sEV Strategies for Neuroimmune Niche Reprogramming in Selected CNS Disorders: Mechanisms, Engineered Delivery, and Translational Readiness

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Stem cell‐ and EV/sEV‐based interventions may reprogram the CNS neuroimmune niche by suppressing glial inflammation, enhancing trophic and synaptic support, stabilizing BBB communication, and improving metabolic resilience. Clinical translation will require mechanism‐linked potency assays, MISEV‐aligned EV reporting, biodistribution, GMP manufacturing,
Wenjing Lu, Junqiang Yan, Hongfang Feng
wiley   +1 more source

Carbon Quantum Dots: From Mechanisms to Biomedical Applications

MedComm, Volume 7, Issue 10, October 2026.
Carbon quantum dots (CQDs) are promising carbon‐based nanomaterials with broad biomedical applications, including bioimaging, drug delivery, biosensing, and tissue regeneration. This Review summarizes the biological mechanisms of CQDs in tissue regeneration, focusing on their regulation of cellular functions, immune responses, and redox balance.
Bingxin Fan, Nianqiang Jin, Nuo Jin, Jiayu Shen, Xinliang Duan, Sichen Han, Yao Yuan, Zilin Wang   +7 more
wiley   +1 more source