Results 61 to 70 of about 2,694 (155)

The Role of EVs in the Aging Hematopoietic System

Aging Cell, Volume 25, Issue 10, October 2026.
Extracellular vesicles from aged bone marrow carry pro‐inflammatory cargo that drives blood stem cell decline, while youthful vesicles restore or maintain stem cell function. Circulating vesicles therefore represent both a readout of hematopoietic aging and a potential therapeutic route.
Esra G. Kosebent, Nathalie Havranek, Karoline Kollmann, Kristina Kirschner, Eszter Doma, Kavya Gupta   +5 more
wiley   +1 more source

Therapeutic potential of stem cells from human exfoliated deciduous teeth infusion into patients with type 2 diabetes depends on basal lipid levels and islet function

Stem Cells Translational Medicine, 2021
Mesenchymal stem cells (MSCs) hold great potential in treating patients with diabetes, but the therapeutic effects are not always achieved. Particularly, the clinical factors regulating MSC therapy in this setting are largely unknown.
Wenwen Li, Xuan Jiao, Jingyun Song, Bingdong Sui, Zhili Guo, Yingji Zhao, Jun Li, Songtao Shi, Qin Huang   +8 more
doaj   +1 more source

New technologies in oral reconstructive medicine: Consensus report of the AAP/OF/SEPA Workshop

Journal of Periodontology, Volume 97, Issue S1, Page S8-S32, September 2026.
Abstract Background The objectives of this Workshop were to evaluate the efficacy of scaffolding technologies for horizontal and vertical ridge augmentation; to evaluate the efficacy of substitute scaffolds for soft tissue augmentation in the context of implant therapy; to evaluate the efficacy of cells and/or biologics combined with scaffolds for ...
Mariano Sanz, Sašo Ivanovski, José Nart, Frank Schwarz, Hom‐Lay Wang, Tara L. Aghaloo, Bilal Al‐Nawas, Gustavo Avila‐Ortiz, Shayan Barootchi, Juan Blanco, Gonzalo Blasi, Nikolaos Donos, Balazs Feher, Irina F. Dragan, Maria L. Geisinger, Adrián Guerrero, Effie Ioannidou, Darnell Kaigler, Yvonne Hernandez‐Kapila, Purnima S. Kumar, Liran Levin, Antonio Liñares, George A. Mandelaris, Paula Matesanz‐Pérez, Alberto Monje, Eduardo Montero, Alberto Ortiz‐Vigón, Joan Otomo‐Corgel, Flavia Q. Pirih, Ausra Ramanauskaite, Isabella Rocchietta, Vanessa Ruiz‐Magaz, Hanae Saito, Nerea Sánchez, Javier Sanz Esporrin, Anton Sculean, Florian M. Thieringer, Daniel S. Thoma, Cristina Valles, Diego Velásquez, David T. Wu, William V. Giannobile   +41 more
wiley   +1 more source

Applications of Mesenchymal Stromal Cells for Treatment of Diseases

MedComm, Volume 7, Issue 9, September 2026.
This schematic summarizes the major therapeutic mechanisms of MSCs across different disease systems and highlights factors associated with MSCs dysfunction, together with current strategies to enhance MSCs function and therapeutic efficacy. This summary diagram illustrates that MSCs exert therapeutic effects in various diseases through multiple ...
Dongmei Xue, Yongsheng Li, Lei Wu
wiley   +1 more source

Teeth as Source of Stem Cells: an Alternative to Ethical Dilemmas

Revista de Bioética y Derecho, 2014
Stem cells have been the main object of study in the Restorative Medicine scientific field. When obtained from embryos, such cells may distinguish in all tissues, although the methods applied to obtain them have to deal with ethical and legal dilemmas ...
Mariana Rezende Machado, Rodrigo Grazinoli Garrido   +1 more
doaj   +1 more source

Characteristics and Therapeutic Potential of Dental Pulp Stem Cells on Neurodegenerative Diseases

Frontiers in Neuroscience, 2020
To evaluate the therapeutic potential of stem cells for neurodegenerative diseases, emphasis should be placed on clarifying the characteristics of the various types of stem cells.
Tomoyuki Ueda, Masatoshi Inden, Taisei Ito, Hisaka Kurita, Isao Hozumi   +4 more
doaj   +1 more source

Phenotyping of Human Pulp Cells After Cryopreservation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 18, September 2026.
ABSTRACT This study aimed to compare cell viability, morphology, cell yield, and stem cell‐associated marker expression of cryopreserved human dental pulp cells (HDPCs) across different passages following thawing and serial in vitro expansion. HDPCs were isolated from three healthy donors, cryopreserved at −80°C for 3 months, and subsequently evaluated
Camila Maura Morais Lima dos Santos, Washington Henrique Themoteo da Silva, Fernanda Rodrigues Guedes, Milla Christian de Paula, Leslie Morse, Ricardo Battaglino, Marcelo José Barbosa Silva, Ana Paula Turrioni   +7 more
wiley   +1 more source

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

iMeta, Volume 5, Issue 4, August 2026.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni, Jiaojiao Xie, Zhichun Zhang, Keming Zhang, Jie Ding, Mingyang Chang, Ying Su, Yunan Zhang, Mingfei Yao, Chengyuan Wang, Yan Yan, Wenjie Fang, Hainv Gao, Xuecong Tian, Yangshuo Li, Xinlin Zhu, Wen Zhang, Wanqing Liao, Gaoyuan Xu, Guojing Chen, Xiaoyi Lv, Chaoqin Yu, Weihua Pan, Vadim Molodtsov, Lanjuan Li, Yue Gao, Wei Zhou   +26 more
wiley   +1 more source

Young small extracellular vesicles rejuvenate replicative senescence by remodeling Drp1 translocation-mediated mitochondrial dynamics

Journal of Nanobiotechnology
Background Human mesenchymal stem cells have attracted interest in regenerative medicine and are being tested in many clinical trials. In vitro expansion is necessary to provide clinical-grade quantities of mesenchymal stem cells; however, it has been ...
Yingying Peng, Tingting Zhao, Shuxuan Rong, Shuqing Yang, Wei Teng, Yunyi Xie, Yan Wang   +6 more
doaj   +1 more source

Effects of chlorhexidine on stem cells from exfoliated deciduous teeth

Journal of the Formosan Medical Association, 2015
Chlorhexidine (CHX) is a type of chemical antiseptic that is widely used in dental practice. Stem cells from human exfoliated deciduous teeth (SHED) are multipotent cells.
Yuan-Yu Tu, Chien-Ying Yang, Rung-Shu Chen, Min-Huey Chen   +3 more
doaj   +1 more source