Carrier‐free nanodrugs for stemness inhibition‐enhanced photodynamic therapy
, 2023 Cancer stem cell (CSC) has been considered a key driver of tumor growth, recurrence, and metastasis due to its self‐renewal and tumor initiation capacities called stemness.
Kaiqi Long +4 more
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‐controlled stemness pathway in paediatric acute leukaemia [PDF]
, 2023 Esperanza-Cebollada E., et al. found a group of 24 microRNAs, to be differentially expressed between two groups of paediatric acute myeloid leukaemia (AML) cases with distinct outcomes.
Erkeland, Stefan J., Stefan J. Erkeland
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Astragaloside IV enhances the sensitivity of breast cancer stem cells to paclitaxel by inhibiting stemness [PDF]
, 2023 Background: Chemotherapy is one of the common treatments for breast cancer. The induction of cancer stem cells (CSCs) is an important reason for chemotherapy failure and breast cancer recurrence. Astragaloside IV (ASIV) is one of the effective components
Heloisa Sobreiro Selistre-de-Araujo +12 more
core
Cancer stemness in hepatocellular carcinoma: mechanisms and translational potential [PDF]
, 2020 Cancer stemness, referring to the stem-cell-like phenotype of cancer cells, has been recognised to play important roles in different aspects of hepatocarcinogenesis.
Tsui, YM, Chan, LK, Ng, IOL
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The effect of extracellular acidosis on the behaviour of mesenchymal stem cells in vitro [PDF]
European Cells & Materials, 2017 The stem cell fraction of a cell population is finely tuned by stimuli from the external microenvironment. Among these stimuli, a decrease of extracellular pH (pHe) may occur in a variety of physiological and pathological conditions, including hypoxia ...
A Massa +6 more
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Transcriptome analysis reveals high tumor heterogeneity with respect to re-activation of stemness and proliferation programs [PDF]
, 2021 Significant alterations in signaling pathways and transcriptional regulatory programs together represent major hallmarks of many cancers. These, among all, include the reactivation of stemness, which is registered by the expression of pathways that are ...
Ivanov, Timofei +16 more
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Bioengineering & Translational Medicine, 2023 Organoids hold inestimable therapeutic potential in regenerative medicine and are increasingly serving as an in vitro research platform. Still, their expanding applications are critically restricted by the canonical culture matrix and system.
Zi‐Yan Xu +8 more
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Stemming on STEM: A STEM Education Framework for Students with Disabilities
Journal of Science Education for Students with Disabilities, 2016 There has been increased attention paid to science, technology, engineering, and mathematics also known as STEM. The focus on STEM has been both educational and occupational. Unfortunately, students with disabilities perform below their peers without disabilities in math and science.
Hwang, Jiwon, Taylor, Jonte C
openaire +3 more sources
Differential regulation of morphology and stemness of mouse embryonic stem cells by substrate stiffness and topography [PDF]
, 2014 The maintenance of stem cell pluripotency or sternness is crucial to embryonic development and differentiation. The mechanical or physical microenvironment of stem cells, which includes extracellular matrix stiffness and topography, regulates cell ...
Long M(龙勉) +5 more
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CellsThe Connexin43 transmembrane protein (Cx43), encoded by the GJA1 gene, is a member of a multigenic family of proteins that oligomerize to form hemichannels and intercellular channels, allowing gap junctional intercellular communication between adjacent ...
Sarah Fournier +3 more
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