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STEM crisis or STEM surplus? Yes and yes [PDF]
Monthly Labor Review, 2015 The last decade has seen considerable concern regarding a shortage of science, technology, engineering, and mathematics (STEM) workers to meet the demands of the labor market. At the same time, many experts have presented evidence of a STEM worker surplus. A comprehensive literature review, in conjunction with employment statistics, newspaper articles,
Xue, Yi, Larson, Richard Charles
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E2F3 accelerates the stemness of colon cancer cells by activating the STAT3 pathway
Frontiers in Oncology, 2023 IntroductionColon cancer is one of the most prevalent malignancies and causes of cancer-related deaths worldwide. Thus, further research is required to explicate the latent molecular mechanisms and look for novel biomarkers. E2F3 has been confirmed to be
Qingkun Gao +5 more
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PLoS ONE, 2017 Cancer stem cell survival is the leading factor for tumor recurrence after tumor-suppressive treatments. Therefore, specific and efficient inhibitors of cancer stemness must be discovered for reducing tumor recurrence.
Chun-Chia Cheng +10 more
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Cells, 2021 Thymosin β4 (Tβ4) is a small, 44-amino acid polypeptide. It has been implicated in multiple processes, including cell movement, angiogenesis, and stemness. Previously, we reported that melanoma cell lines differ in Tβ4 levels.
Aleksandra Makowiecka +7 more
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Hematopoietic stem cell metabolism and stemness
Blood Science, 2019 AbstractHematopoietic stem cells (HSCs) are considered to originate from the aorta-gonad-mesonephros, migrate into fetal liver for a rapid expansion, and eventually reside into a unique hypoxic bone marrow niche, where they maintain their homeostasis throughout their life span.
Dan Huang +4 more
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The effect of extracellular acidosis on the behaviour of mesenchymal stem cells in vitro [PDF]
European Cells & Materials, 2017 The stem cell fraction of a cell population is finely tuned by stimuli from the external microenvironment. Among these stimuli, a decrease of extracellular pH (pHe) may occur in a variety of physiological and pathological conditions, including hypoxia ...
A Massa +6 more
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Bioengineering & Translational Medicine, 2023 Organoids hold inestimable therapeutic potential in regenerative medicine and are increasingly serving as an in vitro research platform. Still, their expanding applications are critically restricted by the canonical culture matrix and system.
Zi‐Yan Xu +8 more
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CellsThe Connexin43 transmembrane protein (Cx43), encoded by the GJA1 gene, is a member of a multigenic family of proteins that oligomerize to form hemichannels and intercellular channels, allowing gap junctional intercellular communication between adjacent ...
Sarah Fournier +3 more
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Stemming on STEM: A STEM Education Framework for Students with Disabilities
Journal of Science Education for Students with Disabilities, 2016 There has been increased attention paid to science, technology, engineering, and mathematics also known as STEM. The focus on STEM has been both educational and occupational. Unfortunately, students with disabilities perform below their peers without disabilities in math and science.
Hwang, Jiwon, Taylor, Jonte C
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Combined oral contraceptive (COC) use in obese adult women dramatically increases the relative risk of developing a pulmonary embolism (PE). The risk of a PE in obese adolescent females taking contraceptives is currently unknown. The purpose of this investigation was to determine the effect of body mass index (BMI) and contraceptive
John Puetz, Joanne Salas
wiley +1 more source