Results 11 to 20 of about 106,531 (314)
YM155 as an inhibitor of cancer stemness simultaneously inhibits autophosphorylation of epidermal growth factor receptor and G9a-mediated stemness in lung cancer cells. [PDF]
PLoS ONE, 2017 Cancer stem cell survival is the leading factor for tumor recurrence after tumor-suppressive treatments. Therefore, specific and efficient inhibitors of cancer stemness must be discovered for reducing tumor recurrence.
Chun-Chia Cheng +10 more
doaj +2 more sources
The role of microRNAs in stemness of cancer stem cells
Oncology Reviews, 2013 Cancer is one of the most important diseases of humans, for which no cure has been found so far. Understanding the causes of cancer can pave the way for its treatment. Alteration in genetic elements such as oncogenes and tumor suppressor genes results in
Seyed Mohammad Ali Hosseini Rad +5 more
doaj +3 more sources
Stemness-driven clusters in ovarian cancer: immune characteristics and prognostic implications [PDF]
Frontiers in OncologyBackgroundOvarian cancer (OC) is the most common malignant gynecological tumor. Cancer cells with high stemness often exhibit resistance to anti-tumor therapies, contributing to recurrence and poor prognosis.
Xinyan Zeng +10 more
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Promotion of cancer cell stemness by Ras [PDF]
, 2021 peer reviewedCancer stem cells (CSC) may be the most relevant and elusive cancer cell population, as they have the exquisite ability to seed new tumors.
CHIPPALKATTI, Rohan +3 more
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Stemness in Cancer: Stem Cells, Cancer Stem Cells, and Their Microenvironment [PDF]
Stem Cells International, 2017 Stemness combines the ability of a cell to perpetuate its lineage, to give rise to differentiated cells, and to interact with its environment to maintain a balance between quiescence, proliferation, and regeneration. While adult Stem Cells display these properties when participating in tissue homeostasis, Cancer Stem Cells (CSCs) behave as their ...
Pedro M. Aponte, Andrés Caicedo
openaire +3 more sources
Stemming vision loss with stem cells [PDF]
Journal of Clinical Investigation, 2010 Dramatic advances in the field of stem cell research have raised the possibility of using these cells to treat a variety of diseases. The eye is an excellent target organ for such cell-based therapeutics due to its ready accessibility, the prevalence of vasculo- and neurodegenerative diseases affecting vision, and the availability of animal models to ...
Valentina, Marchetti +3 more
openaire +2 more sources
, 2022 Background: Pancreatic adenocarcinoma (PAAD) is one of the most aggressive and fatal gastrointestinal malignancies with high morbidity and mortality worldwide.
Jing Zheng (65946) +10 more
core +1 more source
, 2022 Background: Pancreatic adenocarcinoma (PAAD) is one of the most aggressive and fatal gastrointestinal malignancies with high morbidity and mortality worldwide.
Jing Zheng (65946) +10 more
core +1 more source
, 2022 Background: Pancreatic adenocarcinoma (PAAD) is one of the most aggressive and fatal gastrointestinal malignancies with high morbidity and mortality worldwide.
Jing Zheng (65946) +10 more
core +1 more source
, 2022 Background: Pancreatic adenocarcinoma (PAAD) is one of the most aggressive and fatal gastrointestinal malignancies with high morbidity and mortality worldwide.
Jing Zheng (65946) +10 more
core +1 more source