Results 101 to 110 of about 174,911 (284)

Functional characterization of synthetic leukotriene B and its stereochemical isomers. [PDF]

, 1981
Leukotriene B (LTB), a potent lipid chemotactic factor for neutrophils, is 5S,12R-dihydroxy-6,14-cis,8,10-trans-eicosatetraenoic acid (Fig 1), based upon direct comparison of natural LTB with synthetic 5S,12R-dihydroxy-6,8,10,14-eicosatetraenoic acid (5 ...
Austen, K, Corey, E, Drazen, J, Goetzl, Edward, Lewis, R, Soter, N   +5 more
core   +1 more source

A detailed view on 1,8-cineol biosynthesis by Streptomyces clavuligerus

Beilstein Journal of Organic Chemistry, 2016
The stereochemical course of the cyclisation reaction catalysed by the bacterial 1,8-cineol synthase from Streptomyces clavuligerus was investigated using stereospecifically deuterated substrates.
Jan Rinkel, Patrick Rabe, Laura zur Horst, Jeroen S. Dickschat   +3 more
doaj   +1 more source

Synthesis of cyclopropyl-substituted furans by Brønsted acid promoted cascade reactions [PDF]

, 2015
Chloroacetic acid promotes an efficient and diastereoselective intramolecular cascade reaction of electron-deficient ynenones to deliver products featuring a 2,3,5-trisubstituted furan bearing a fused cyclopropyl substituent at the 5-position ...
Achmatowicz, Albrecht, Barluenga, Benary, Boto, Casey, Ciufolini, Clark, Corma, Csuk, Csuk, Donaldson, Donohoe, Fedoryński, Feist, Fritz, Gandini, Gilchrist, González, González, Hashmi, Hou, Högberg, Jung, Knorr, Kobayashi, Krasnaya, Kuroda, Lebel, Li, Li, Lipshutz, Ma, MacMillan, Paal, Pellissier, Ripaud, Sperry, Vicente, Wang, Wessjohann, Wipf, Wu, Xia, Yang, Zhang, Zimmerman   +46 more
core   +2 more sources

Chemical Synthesis of the Lantibiotic Lacticin 481 Reveals the Importance of Lanthionine Stereochemistry

Journal of the American Chemical Society, 2013
Lantibiotics are a family of antibacterial peptide natural products characterized by the post-translational installation of the thioether-containing amino acids lanthionine and methyllanthionine.
P. Knerr, W. A. van der Donk
semanticscholar   +1 more source

Synergistic Anti-Candida Activity of Bengazole A in the Presence of Bengamide A †. [PDF]

, 2019
Bengazoles A⁻G from the marine sponge Jaspis sp. exhibit potent in vitro antifungal activity against Candida spp. and other pathogenic fungi. The mechanism of action (MOA) of bengazole A was explored in Candida albicans under both liquid culture and ...
Cheng, Tina, Jamison, Matthew T, Molinski, Tadeusz F, Wang, Xiao   +3 more
core  

Crystal structure, computational study, and Hirshfeld analysis of exo-1,2,3,5-tetraphenyl-1a',9b'-dihydrospiro[bicyclo[3.1.0]hexane-6,1′-cyclopropa[l]phenanthren]-2-en-4-one

Acta Crystallographica Section E: Crystallographic Communications
The reaction of dibenzonorcarynyliden(e/oid) with phencyclone was recently reported to give a congested spiropentane with endo stereochemistry. Herein we report that, in sharp contrast, an analogous reaction using tetracyclone, instead of phencyclone ...
Alexander D. Roth, Dasan M. Thamattoor
doaj   +1 more source

Stereochemical course of hydrolytic reaction catalyzed by alpha-galactosidase from cold adaptable marine bacterium of genus Pseudoalteromonas

Frontiers in Chemistry, 2014
The recombinant α-galactosidase of the marine bacterium (α-PsGal) was synthesized with the use of the plasmid 40Gal, consisting of plasmid pET-40b (+) (Novagen) and the gene corresponding to the open reading frame of the mature α-galactosidase of marine ...
Irina Yu Bakunina, Larissa A Balabanova, Vasiliy A Golotin, Lyubov V Slepchenko, Lyubov V Slepchenko, Vladimir V Isakov, Valeriy A Rasskazov   +6 more
doaj   +1 more source

AN INDEX TO THE LITERATURE OF STEREOCHEMISTRY [PDF]

, 1892
Arnold Eiloart
openalex   +1 more source

Survey of Pharmacological Activity and Pharmacokinetics of Selected β-Adrenergic Blockers in Regard to Their Stereochemistry

Applied Sciences, 2019
The present survey concentrates on pharmacodynamics and pharmacokinetics of selected β-adrenergic blockers from the point of view of their stereochemistry. It could be shown that the activity in the arylaminoethanol and aryloxyaminopropanol group of
Ružena Čižmáriková, Ladislav Habala, Jindra Valentová, Mário Markuliak   +3 more
doaj   +1 more source

The Sequence of the Enterococcal Cytolysin Imparts Unusual Lanthionine Stereochemistry

Nature Chemical Biology, 2013
The enterococcal cytolysin is a two-component lantibiotic of unknown structure with hemolytic activity that is important for virulence. We prepared cytolysin by co-expression of each precursor peptide with the synthetase CylM in E.
Weixin Tang, W. A. van der Donk
semanticscholar   +1 more source