Results 131 to 140 of about 158,943 (323)
Quantifying biogenic bias in screening libraries. [PDF]
, 2009 In lead discovery, libraries of 10(6) molecules are screened for biological activity. Given the over 10(60) drug-like molecules thought possible, such screens might never succeed.
Hert, Jérôme +4 more
core +1 more source
Direct imaging of carbohydrate stereochemistry [PDF]
arXivCarbohydrates, essential biological building blocks, exhibit functional mechanisms tied to their intricate stereochemistry. Subtle stereochemical differences, such as those between the anomers maltose and cellobiose, lead to distinct properties due to their differing glycosidic bonds; the former is digestible by humans, while the latter is not.
arxiv
Proteins: Structure, Function, and Bioinformatics, 2009 A correct alignment is an essential requirement in homology modeling. Yet in order to bridge the structural gap between template and target, which may not only involve loop rearrangements, but also shifts of secondary structure elements and repacking of ...
E. Krieger +8 more
semanticscholar +1 more source
Poučevanje stereokemije z multimedijo in s praktičnimi modeli: odnos med zmožnostmi naravoslovnega mišljenja pri študentih in učinkovitostjo vrste modela [PDF]
This paper presents an analysis of the use of multimedia and hands-on models on university students\u27 understanding of stereochemistry. The relationship between students\u27 scientific reasoning skills and their understanding of stereochemistry was ...
Devetak, Iztok +5 more
core +1 more source
THE STEREOCHEMISTRY OF THE PIMARIC ACIDS [PDF]
, 1959 O. E. Edwards, Robert Howe
openalex +1 more source
Optically active beams: non-reciprocal optical activity in free space induced by spin-orbital interaction of light [PDF]
arXiv, 2019 Optical activity, the power of a medium to rotate the polarization of a light beam, has contributed significantly to molecular structure assessments in stereochemistry, biomolecular science and crystallography. Thus far, it is commonly believed that optical activity is manifested only in the chiral media which can give rise to circular birefringence of
arxiv
Molecular Therapy: Nucleic Acids, 2021 The 599 peptide has been previously shown to effectively deliver small interfering RNAs (siRNAs) to cancer cells, inducing targeted-oncogene silencing, with a consequent inhibition of tumor growth. Although effective, this study was undertaken to advance
Charles E. Holjencin +10 more
doaj
Five-membered ring annelation in [2.2]paracyclophanes by aldol condensation
Beilstein Journal of Organic Chemistry, 2014 Under basic conditions 4,5,12,13-tetraacetyl[2.2]paracyclophane (9) cyclizes by a double aldol condensation to provide the two aldols 12 and 15 in a 3:7 ratio.
Henning Hopf +2 more
doaj +1 more source