Results 191 to 200 of about 118,878 (273)

The Multifaceted Legacy of Thalidomide: Chemistry and Biology Driving Modern Drug Design

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Thalidomide serves as a molecular nexus linking chemistry and biology: advances in synthesis and structural understanding enable protein degradation technologies, while its immunomodulatory activity underpins anti‐inflammatory and anticancer therapies.
Konstantina Nikovia, Michael Kapsalis, Michael Georgoulakis, Athanasios Panousis, Constantinos G. Neochoritis   +4 more
wiley   +1 more source

Rapid and Stereoselective Ring‐Opening Polymerization of rac‐Lactide Enabled by a Chiral Cyclopropenimine–Thiourea Catalyst

Angewandte Chemie, Volume 138, Issue 15, 6 April 2026.
Chiral cyclopropenimine–thiourea organocatalysts enabled both high reactivity and precise stereocontrol in the ring‐opening polymerization of rac‐lactide. The bifunctional system exhibited a TOF up to 1,710 h−1 with Pm = 0.90 at 25°C, and achieved Pm = 0.99 at −78°C while maintaining a TOF of 16.3 h−1.
Sumin Lee, Hooseung Lee, Hyeongwoo Nam, Seungyun Jo, Minseong Kim, Dongwook Kim, Du Yeol Ryu, Sarah Yunmi Lee, Byeong‐Su Kim   +8 more
wiley   +2 more sources

Editor's Choice JAAG: a JSON input file assembler for AlphaFold 3 with glycan integration. [PDF]

Glycobiology
Huang C, Moremen KW.
europepmc   +1 more source

Back to the Electrofuture: Named Reactions Powered by Electroorganic Syntheses

ChemSusChem, Volume 19, Issue 7, 14 April 2026.
Bridging classical named reactions with modern electroorganic chemistry, this review presents how electrochemical strategies can revive and reinterpret historically significant transformations, highlighting their emerging potential as sustainable alternatives in contemporary organic synthesis.
Debajit Maiti, Yoonji Heo, Geon Kang, Min Kim, Isaac Choi   +4 more
wiley   +1 more source

Caylobolide B: Structure Revision, Total Synthesis, Biological Characterization, and Discovery of New Analogues. [PDF]

Angew Chem Int Ed Engl
George MRP, Elsadek LA, Deering M, de Almeida LC, Tyler JL, Noble A, Paul VJ, Luesch H, Butts CP, Aggarwal VK.   +9 more
europepmc   +1 more source

Photocatalytic Stereoselective Editing of Alkynes to 3D Molecules via Hydrogen Atom Transfer-Mediated Dynamic Epimerization. [PDF]

Nat Commun
Gu Z, Zeng T, Yuan Z, Zheng H, Zhu G.
europepmc   +1 more source

Author Correction: Tripterygium wilfordii cytochrome P450s catalyze the methyl shift and epoxidations in the biosynthesis of triptonide. [PDF]

Nat Commun
Kongstad KT, Hansen NL, Kjaerulff L, Heck QK, Forman V, Staerk D, Møller BL, Andersen-Ranberg J.   +7 more
europepmc   +1 more source

Ultrasound-Triggered Self-Assembly of Discrete Oligourethanes into Supramolecular Gels: Importance of Stereocenter Sequence. [PDF]

ACS Macro Lett
Castellanos E, Dudziak W, Groch P, Szuwarzyński M, Szweda R.   +4 more
europepmc   +1 more source

Preparation of Organometallic Complexed Sugars:  Hetero Diels−Alder Reactivity of Tricarbonyl(formyltrimethylenemethane)- iron [PDF]

, 1997
Donaldson, William, Kleindl, Paul J.
core   +1 more source

Synthesis of bacteriochlorophyll <i>a</i>. [PDF]

Chem Sci
Chung DTM, Nguyen KC, Liu Y, Lindsey JS.
europepmc   +1 more source