Results 181 to 190 of about 63,316 (301)

Small molecules as arthropod kinin receptor antagonists, feeding modulators, or novel mosquitocidal agents

open access: yesPest Management Science, Volume 82, Issue 7, Page 6842-6863, July 2026.
A two‐pronged screen of small molecules – (1) on recombinant kinin receptor and (2) through topical application – identifies kinin receptor antagonists, feeding behavior modulators, and new mosquitocidal molecules. Abstract BACKGROUND Aedes aegypti and Culex quinquefasciatus mosquitoes are primary vectors for numerous human and animal pathogens and ...
Bianca M. Henriques‐Santos   +1 more
wiley   +1 more source

Stereochemistry-aware string-based molecular generation. [PDF]

open access: yesPNAS Nexus
Tom G   +4 more
europepmc   +1 more source

1,1‐and 1,2‐Diborylalkenes: Preparation and Synthetic Applications

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 12, 17 June 2026.
In this review, we highlight recent advances in the synthesis and reactivity of 1,1‐diborylalkenes and 1,2‐diborylalkenes, along with various transformations leading to C‐C, C‐heteroatom, and multicomponent products. By providing a comprehensive and practical resource, this review aims to assist researchers in exploring the synthetic utility of 1,1 and
Jayaram Vankudoth   +2 more
wiley   +1 more source

Racemisation of Amino Acids: From Synthetic Challenge to Biological Significance

open access: yesChemBioChem, Volume 27, Issue 11, 15 June 2026.
Racemisation, once considered an undesirable synthetic side reaction, also occurs naturally in amino acids and influences biological processes. Evidence links stereochemical conversion to ageing, protein turnover, and cellular development. This review examines mechanisms, control strategies in synthesis, applications and implications in physiology ...
Othman Al Musaimi
wiley   +1 more source

Ring‐Opening Arylation of Cyclic Diaryliodoniums via Cyclic Triaryliodanes as Aryne Precursors and Dynamic Aryl Reservoirs

open access: yesAngewandte Chemie, Volume 138, Issue 24, 8 June 2026.
Cyclic diaryliodonium salts engage aryl Grignard reagents to trigger a self‐propagating aryne–arylation cycle. Transient cyclic triaryliodanes serve as aryne precursors and dynamic aryl reservoirs, delivering iodine‐capped teraryls with predominant meta‐selectivity. The preserved C─I bond enables outward π‐extension or inward recyclization.
Daichi Ikeshita   +2 more
wiley   +2 more sources

Stereocontrol as a tool for shaping abiotic, sequence-defined oligourethanes.

open access: yesPolym Chem
Njoku S   +8 more
europepmc   +1 more source

Stereochemical Terminology in Chiral Drugs: Still Between Confusion and Misinterpretation. [PDF]

open access: yesACS Med Chem Lett
García de la Concepción J   +2 more
europepmc   +1 more source

Structural Basis for Nucleobase Activation by the Adenine DNA Glycosylase MutY

open access: yesChemBioChem, Volume 27, Issue 11, 15 June 2026.
DNA glycosylase MutY engages its adenine nucleobase substrate in a syn orientation with a catalytic Glu. X‐ray crystal structures of MutY with Glu replaced suggest that a disengaged “on hold” state with anti nucleobase orientation may explain how MutY avoids catastrophic activity at inappropriate adenines.
L. Peyton Russelburg   +4 more
wiley   +1 more source

1,4‐Digermacyclopenta‐1,3‐diene: Continuous Cyclic σ*–π Delocalization Enables Aromatic Stabilization in a Heavy‐Element 4π System

open access: yesAngewandte Chemie, Volume 138, Issue 24, 8 June 2026.
A five‐membered digermacycle exhibits an unusual 4π electron delocalization enabled by σ*(Ge–C)–π coupling within a nearly planar framework. Combined experimental and theoretical analyses reveal a continuous cyclic delocalization pathway, highlighting σ*–π interactions as a design principle for aromatic stabilization beyond classical π‐conjugated ...
Daichi Uchida   +2 more
wiley   +2 more sources

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