Results 201 to 210 of about 177,307 (324)

Synthesis of Novel BINOL Analogs: 3,3′‐Dicarbonyl‐1,1′‐binaphthyl‐4,4′‐diols as Precursors to the Uncharted 5,5′‐Binaphtho[2,1‐d]isoxazole

European Journal of Organic Chemistry, EarlyView.
The parent 5,5′‐binaphtho[2,1‐d]isoxazole and its 3,3′‐dimethyl and 3,3′‐diphenyl derivatives are synthesized via condensation of the respective dicarbonyl compounds with hydroxylamine, followed by cyclodehydration of the resulting dioximes. The dicarbonyl precursors are obtained through 4‐ or 6‐step sequences from 1‐naphthol or 1‐naphthaldehyde ...
Marek Surowiec, Ioannis E. Gerontitis, Petros G. Tsoungas, Panteleimon G. Takis, Panagiotis Stathopoulos, Erietta Pouliou, George Varvounis   +6 more
wiley   +1 more source

Mirror, mirror on the wall ... stereochemistry in therapeutics. [PDF]

, 1994
Dan M. Roden
openalex   +1 more source

Overall Retention of Methyl Stereochemistry during B₁₂-Dependent Radical SAM Methyl Transfer in Fosfomycin Biosynthesis

, 2021
Martin I. McLaughlin, Katharina Pallitsch, Gabriele Wallner, Wilfred A. van der Donk, Friedrich Hammerschmidt   +4 more
openalex   +1 more source

Cell‐Penetrating Poly(disulfide)s

Helvetica Chimica Acta, EarlyView.
The first 10 years of cell‐penetrating poly(disulfide)s (CPDs) are reviewed comprehensively. CPDs are prepared by ring‐opening polymerization of cyclic disulfides. The many sidechain structures and diverse biological applications realized so far beyond the original arginines identify CPDs as the most popular current delivery system that operates with ...
Michael Cognet, Giacomo Renno, Nicholas Rose, Yuheng Zhang, Pierre Josso, Julia Moreno, Xudong Ren, Jules Bouffard, Saidbakhrom Saidjalolov, Naomi Sakai, Stefan Matile   +10 more
wiley   +1 more source

The Relation Between Stereochemistry and Biological Activity of Platinum(II) Complexes Chelated with Chiral Diamine Ligands: An Intricate Problem

, 2007
François Dufrasne, M. Galanski
openalex   +2 more sources

Stereochemistry and charge density of hydrogen bonds with oxygen acceptor [PDF]

, 2011
Christian Jelsch, Maqsood Ahmed, Benoît Guillot, S. Domagała, Claude Lecomte   +4 more
openalex   +1 more source

A “One‐Pot” Metal‐Free Synthesis and Evaluation of Antiproliferative Activity of Diversely Functionalized Pyrrolidine‐2‐Ones

Journal of Heterocyclic Chemistry, EarlyView.
A new “one‐pot” metal‐free stereoselective method for the synthesis of novel diversely functionalized pyrrolidine‐2‐ones from N‐alkyl‐ or N‐arylsulfonamidoacetophenones was developed. The majority of obtained compounds possess low micromolar antiproliferative activities.
Samuel Dick, Matija Bekic, David Meuter, Gary Angles, Victoria Sena, Tatiana Timofeeva, Arturo Lopez Villalobos, Liliya V. Frolova   +7 more
wiley   +1 more source

Correction to "Incorporation of Multiple β²‑Hydroxy Acids into a Protein in Vivo Using an Orthogonal Aminoacyl-tRNA Synthetase". [PDF]

ACS Cent Sci
Hamlish NX, Abramyan AM, Shah B, Zhang Z, Schepartz A.   +4 more
europepmc   +1 more source

Highly Diastereo- and Enantioselective Allylboration of Aldehydes using alpha-Substituted Allyl/Crotyl Pinacol Boronic Esters via in Situ Generated Borinic Esters [PDF]

, 2013
Althaus M., Andersen M. W., Batey R. A., Batey R. A., Beckmann E., Blais J., Brown H. C., Brown H. C., Brown H. C., Brown H. C., Bubnov Y. N., Carosi L., Carosi L., Chemler S. R., Chen M., Chen M., Christine L. Willis, Cmrecki V., Cole T. E., Denmark S. E., Fang G. Y., Flamme E. M., Gonzalez A. Z., Guzman-Martinez A., Hancock K. G., Helen K. Scott, Hesse M. J., Hoffmann R. W., Hoffmann R. W., Hoffmann R. W., Hoffmann R. W., Hoffmann R. W., Hoffmann R. W., Ito H., Jack L.-Y. Chen, Kennedy J. W. J., Kister J., Kliman L. T., Kramer G. W., Lachance H., Larouche-Gauthier R., Matteson D. S., Matthew J. Hesse, Midland M. M., Park J. K., Pelz N. F., Peng F., Peng F., Pietruszka J., Pietruszka J., Posseme F., Pulis A., Ramachandran P. V., Shiner C. S., Sonawane R. P., Stymiest J. L., Varinder K. Aggarwal, Webster M. P., Woodward A. R., Yamamoto Y., Zschage O.   +60 more
core   +1 more source

Stereochemistry of Furfural Reduction by a Saccharomyces cerevisiae Aldehyde Reductase That Contributes to In Situ Furfural Detoxification

, 2010
Michael J. Bowman, Douglas B. Jordan, Karl E. Vermillion, Jay D. Braker, Jaewoong Moon, Z. Lewis Liu   +5 more
openalex   +2 more sources