Results 31 to 40 of about 177,307 (324)

Chiral Aspects of Local Anesthetics

open access: yesMolecules, 2020
Thanks to the progress made in chemical technology (particularly in the methodologies of stereoselective syntheses and analyses) along with regulatory measures, the number of new chiral drugs registered in the form of pure enantiomers has increased over ...
Ružena Čižmáriková   +4 more
doaj   +1 more source

Chemistry, Cyclophosphamide, Cancer Chemotherapy, and Serendipity: Sixty Years On

open access: yesSubstantia, 2021
Cambridge Dictionary: serendipity | noun | the phenomenon of finding interesting or valuable things by chance. The year 2019 marked the 60th anniversary of the approval of cyclophosphamide (CP) as an anticancer by the U.S.
Gerald Zon
doaj   +1 more source

Stereoisomerism in pentaerythritol-bridged cyclotriphosphazene tri-spiranes: spiro and ansa 1,3-propanediyldioxy disubstituted derivatives [PDF]

open access: yes, 2005
Four isomeric products were isolated and purified from the reaction of 1,3-propanediol with the tetra-spirane cyclophosphazene-organophosphate compound (1): viz. the di-monospiro (2a), di-monoansa (2b) and two monospiro-monoansa derivatives (2c) and (2d).
Aylin, U.   +6 more
core   +1 more source

Stereochemistry

open access: yesDefinitions, 2019
The study of the spatial groups that affect the properties of atoms within molecules.
Graham Patrick
semanticscholar   +1 more source

Organic chemistry lecture course and exercises based on true scale models

open access: yesChemistry Teacher International, 2020
3D models of chemical structures are an important tool for chemistry lectures and exercises. Usually, simplified models based on standard bond length and angles are used.
Lederle Felix, Hübner Eike G.
doaj   +1 more source

Fast and Accurate Prediction of Refractive Index of Organic Liquids with Graph Machines

open access: yesMolecules, 2023
The refractive index (RI) of liquids is a key physical property of molecular compounds and materials. In addition to its ubiquitous role in physics, it is also exploited to impart specific optical properties (transparency, opacity, and gloss) to ...
François Duprat   +3 more
doaj   +1 more source

Addition of Di(trimethylsilyl) Phosphite to Schiff Bases of 2,5-Diformylfuran [PDF]

open access: yes, 2011
A series of 2,5-Furanyl-bis-(aminomethylphosphonic Acids) has been synthesized by the addition of di(trimethylsilyl) phosphite to azomethine bond of achiral Schiff bases derved from 2,5-diformylfuran.
Ciechańska, Magdalena   +3 more
core   +1 more source

The End of the Beginning of Mechanical Stereochemistry

open access: yesAccounts of Chemical Research
Conspectus Stereochemistry has played a key role in the development of synthetic chemistry for the simple reason that the function and properties of most molecules, from medicine to materials science, depend on their shape and thus the stereoisomer used.
S. Goldup
semanticscholar   +1 more source

DAG tales: the multiple faces of diacylglycerol—stereochemistry, metabolism, and signaling

open access: yesCellular and Molecular Life Sciences, 2015
The neutral lipids diacylglycerols (DAGs) are involved in a plethora of metabolic pathways. They function as components of cellular membranes, as building blocks for glycero(phospho)lipids, and as lipid second messengers.
Thomas O. Eichmann, A. Lass
semanticscholar   +1 more source

Plasma analysis of di- and trihydroxycholestanoic acid diastereoisomers in peroxisomal α-methylacyl-CoA racemase deficiency

open access: yesJournal of Lipid Research, 2001
We identified a new peroxisomal disorder caused by a deficiency of the enzyme α-methylacyl-coenzyme A (CoA) racemase. Patients with this disorder show elevated plasma levels of pristanic acid and the bile acid intermediates di- and trihydroxycholestanoic
Sacha Ferdinandusse   +5 more
doaj   +1 more source

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