Results 11 to 20 of about 63,316 (301)
The Stereochemistry of Ketoreduction [PDF]
Chemistry & Biology, 2005 In this issue of Chemistry & Biology, Leadlay and coworkers report overproduction of a number of ketoreductase domains from modular polyketide synthases. These discrete enzymes allow the stereochemistry of polyketide ketoreduction to be studied in isolation.
Caffrey, Patrick
openaire +3 more sources
Stereochemistry of the Brivaracetam Diastereoisomers [PDF]
Chirality, 2016 AbstractThe stereochemistry of all four stereoisomers of brivaracetam was determined using vibrational circular dichroism (VCD) spectroscopy. By comparing experimentally obtained VCD spectra and computationally simulated ones, the absolute configurations can be confidently assigned without prior knowledge of their relative stereochemistry.
Qiu, Shi +5 more
openaire +5 more sources
Stereochemistry-Tunable Isocyanide-Based Polymerization
, 2021 Regulation of stereochemistry is one of the most important research focuses in synthetic polymer chemistry; however, this area should be further developed.
Tianyu Cheng +11 more
core +1 more source
Stereochemistry-Controlled Mechanical Properties and Degradation in 3D-Printable Photosets
, 2021 Stereochemistry provides an appealing handle by which to control the properties of small molecules and polymers. While it is established that stereochemistry in linear polymers affects their bulk mechanical properties, the application of this concept to ...
Anissa L. Khalfa (11570389) +5 more
core +1 more source
Stereochemistry and Total Synthesis of Neonorhalichondrin B
, 2023 The first total synthesis of neonorhalichondrin B has been completed and the previously undetermined left half sidechain stereochemistry has been elucidated.
Rachelle, Quach +2 more
core +1 more source
Confirmation of the stereochemistry of spiroviolene
Beilstein Journal of Organic Chemistry, 2023 We confirm the previously revised stereochemistry of spiroviolene by X-ray crystallographically characterizing a hydrazone derivative of 9-oxospiroviolane, which is synthesized by hydroboration/oxidation of spiroviolene followed by oxidation of the resultant hydroxy group.
Yao Kong +9 more
openaire +3 more sources
Mannich base-connected syntheses mediated by ortho-quinone methides
Beilstein Journal of Organic Chemistry, 2018 This article provides an overview about specifically modified Mannich reactions where the process involves an ortho-quinone methide (o-QM) intermediate.
Petra Barta +2 more
doaj +1 more source
Marine Drugs, 2022 NMR data prediction is increasingly important in structure elucidation. The impact of force field selection was assessed, along with geometry and energy cutoffs.
Cristina Cuadrado +2 more
doaj +1 more source
Molecular Therapy: Nucleic Acids, 2021 The 599 peptide has been previously shown to effectively deliver small interfering RNAs (siRNAs) to cancer cells, inducing targeted-oncogene silencing, with a consequent inhibition of tumor growth. Although effective, this study was undertaken to advance
Charles E. Holjencin +10 more
doaj +1 more source
[1,3]/[1,4]-Sulfur atom migration in β-hydroxyalkylphosphine sulfides
Beilstein Journal of Organic Chemistry, 2020 β-Hydroxyalkylphosphine sulfides undergo [1,3]- or [1,4]-sulfur atom phosphorus-to-carbon migration in the presence of Lewis or Brønsted acids. The direction of sulfur atom migration depends on the type of acid used for the reaction. In the presence of a
Katarzyna Włodarczyk +2 more
doaj +1 more source