Results 31 to 40 of about 63,316 (301)

Ceramide structural features required to stimulate ABCA1-mediated cholesterol efflux to apolipoprotein A-I

Journal of Lipid Research, 2006
Ceramide is a component of the sphingomyelin cycle and a well-established lipid signaling molecule. We recently reported that ceramide specifically increased ABCA1-mediated cholesterol efflux to apolipoprotein A-I (apoA-I), a critical process that leads ...
Amy B. Ghering, W. Sean Davidson
doaj   +1 more source

Topics in Stereochemistry

, 2006
Topics in Stereochemistry, previously edited by "the father of stereochemistry" Ernest L. Eliel, is a longstanding, successful series covering the most important advances in the field.
Siegel, Jay S., Denmark, Scott E.
core   +1 more source

Recent Advances in Stereochemistry Reveal Classification Shortcomings

, 2020
We contend that the Polytope model utilized by IUPAC to specify stereoisomerism for species MLn with n > 3 should be universally applied. Such application recently led to the synthesis of isolable compounds displaying a new fundamental form of isomerism,
Peter J., Canfield, Linda J., Govenlock, Jeffrey, Reimers, Maxwell J., Crossley   +3 more
core   +1 more source

Teaching Stereochemistry with Multimedia and Hands-On Models: The Relationship between Students' Scientific Reasoning Skills and The Effectiveness of Model Type

Center for Educational Policy Studies Journal
This paper presents an analysis of the use of multimedia and hands-on models on university students’ understanding of stereochemistry. The relationship between students’ scientific reasoning skills and their understanding of stereochemistry was also ...
Rooserina Kusumaningdyah, Iztok Devetak, Yudhi Utomo, Effendy Effendy, Daratu Putri, Habiddin Habiddin   +5 more
doaj   +1 more source

Amino Alcohols from the Ascidian Pseudodistoma sp.

Marine Drugs, 2014
Seven new amino alcohol compounds, pseudoaminols A–G (1–7), were isolated from the ascidian Pseudodistoma sp. collected off the coast of Chuja-do, Korea.
Tae Hyung Won, Minjung You, So-Hyoung Lee, Boon Jo Rho, Dong-Chan Oh, Ki-Bong Oh, Jongheon Shin   +6 more
doaj   +1 more source

Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A

Angewandte Chemie, EarlyView.
Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham, Edward S. Hems, Daniel C. L. Van, Justin E. Clarke, Sergey Nepogodiev, Julius S. P. Adamson, Christian Bassi, Michael E. Webb, Glyn R. Hemsworth, Orde Q. Munro, Barrie Wilkinson, Ryan F. Seipke   +11 more
wiley   +2 more sources

Stereocontrolled synthesis and nuclear magnetic resonance analysis of boranophosphate/phosphate chimeric oligonucleotides

Royal Society Open Science
This report describes the stereoselective synthesis of boranophosphate/phosphate (PB/PO) chimeric oligodeoxynucleotides (ODNs) and the nuclear magnetic resonance (NMR) analysis of oligomers containing PB linkages.
Kiyoshi Kakuta, Taiichi Sakamoto, Hajime Sato, Kazuki Sato, Takeshi Wada   +4 more
doaj   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

Insights into the Phytochemistry of the Cuban Endemic Medicinal Plant Phyllanthus orbicularis: Fideloside, a Novel Bioactive 8-C-glycosyl 2,3-Dihydroflavonol

Molecules, 2019
Phyllanthus orbicularis (Phyllanthaceae) is an endemic evergreen tropical plant of Cuba that grows in the western part of the island and is used in traditional medicine as an infusion.
Antonio Francioso, Katrin Franke, Claudio Villani, Luciana Mosca, Maria D’Erme, Stefan Frischbutter, Wolfgang Brandt, Angel Sanchez-Lamar, Ludger Wessjohann   +8 more
doaj   +1 more source

Synthesis and Oxidative Transformations of New Chiral Pinane-Type γ-Ketothiols: Stereochemical Features of Reactions

Molecules, 2021
Chiral γ-ketothiols, thioacetates, thiobenzoate, disulfides, sulfones, thiosulfonates, and sulfonic acids were obtained from β-pinene for the first time.
Olga M. Lezina, Svetlana N. Subbotina, Larisa L. Frolova, Svetlana A. Rubtsova, Denis V. Sudarikov   +4 more
doaj   +1 more source