Results 31 to 40 of about 118,878 (273)

Further studies on the substrate spectrum of phytanoyl-CoA hydroxylase

Journal of Lipid Research, 2003
Refsum disease is a peroxisomal disorder characterized by adult-onset retinitis pigmentosa, anosmia, sensory neuropathy, ataxia, and an accumulation of phytanic acid in plasma and tissues.
Veerle Foulon, Stanny Asselberghs, Wendy Geens, Guy P. Mannaerts, Minne Casteels, Paul P. Van Veldhoven   +5 more
doaj   +1 more source

Converting 1,1‐Bisborylalkanes into 1,2‐Bisborylalkanes Enabled by Iron Ligand‐to‐Metal Charge Transfer (LMCT) Photocatalysis

Angewandte Chemie, EarlyView.
1,2‐Bisborylalkanes are valuable intermediates for chemical synthesis as they could serve as a platform to generate value‐added products with two distinct functional groups at vicinal positions. A novel strategy to synthesize 1,2‐bisborylalkanes via Fe ligand‐to‐metal charge transfer (LMCT) photocatalysis is developed.
Zheye Zhang, George Chen, Michael Li, Carla Slebodnick, Diego Troya, Ming Chen   +5 more
wiley   +2 more sources

Teaching Stereochemistry with Multimedia and Hands-On Models: The Relationship between Students' Scientific Reasoning Skills and The Effectiveness of Model Type

Center for Educational Policy Studies Journal
This paper presents an analysis of the use of multimedia and hands-on models on university students’ understanding of stereochemistry. The relationship between students’ scientific reasoning skills and their understanding of stereochemistry was also ...
Rooserina Kusumaningdyah, Iztok Devetak, Yudhi Utomo, Effendy Effendy, Daratu Putri, Habiddin Habiddin   +5 more
doaj   +1 more source

Ceramide structural features required to stimulate ABCA1-mediated cholesterol efflux to apolipoprotein A-I

Journal of Lipid Research, 2006
Ceramide is a component of the sphingomyelin cycle and a well-established lipid signaling molecule. We recently reported that ceramide specifically increased ABCA1-mediated cholesterol efflux to apolipoprotein A-I (apoA-I), a critical process that leads ...
Amy B. Ghering, W. Sean Davidson
doaj   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

Stereocontrolled synthesis and nuclear magnetic resonance analysis of boranophosphate/phosphate chimeric oligonucleotides

Royal Society Open Science
This report describes the stereoselective synthesis of boranophosphate/phosphate (PB/PO) chimeric oligodeoxynucleotides (ODNs) and the nuclear magnetic resonance (NMR) analysis of oligomers containing PB linkages.
Kiyoshi Kakuta, Taiichi Sakamoto, Hajime Sato, Kazuki Sato, Takeshi Wada   +4 more
doaj   +1 more source

Review: Marine natural products [PDF]

, 2005
This review covers the literature published in 2003 for marine natural products, with 619 citations (413 for the period January to December 2003) referring to compounds isolated from marine microorganisms and phytoplankton, green algae, brown algae, red ...
Blunt, John W., Copp, Brent R., Munro, Murray H.G., Northcote, Peter T., Prinsep, Michèle R.   +4 more
core   +3 more sources

Nickel‐Catalyzed Enantioconvergent Arylation of Unactivated Cyclic Electrophiles: Asymmetric Synthesis of 3‐Substituted Pyrrolidines

Angewandte Chemie, EarlyView.
Metal‐catalyzed enantioconvergent substitutions of unactivated cyclic electrophiles by organometallic nucleophiles have not previously been reported. Herein, a chiral nickel catalyst is described that achieves this objective, coupling 3‐iodopyrrolidine derivatives with arylzinc nucleophiles.
Ting Hei Matthew Wong, Xiaoyu Tong, Gregory C. Fu   +2 more
wiley   +2 more sources

Amino Alcohols from the Ascidian Pseudodistoma sp.

Marine Drugs, 2014
Seven new amino alcohol compounds, pseudoaminols A–G (1–7), were isolated from the ascidian Pseudodistoma sp. collected off the coast of Chuja-do, Korea.
Tae Hyung Won, Minjung You, So-Hyoung Lee, Boon Jo Rho, Dong-Chan Oh, Ki-Bong Oh, Jongheon Shin   +6 more
doaj   +1 more source

Synthesis and Oxidative Transformations of New Chiral Pinane-Type γ-Ketothiols: Stereochemical Features of Reactions

Molecules, 2021
Chiral γ-ketothiols, thioacetates, thiobenzoate, disulfides, sulfones, thiosulfonates, and sulfonic acids were obtained from β-pinene for the first time.
Olga M. Lezina, Svetlana N. Subbotina, Larisa L. Frolova, Svetlana A. Rubtsova, Denis V. Sudarikov   +4 more
doaj   +1 more source