Results 61 to 70 of about 176,257 (369)
An Ultrapotent, Ultraeconomical, Antifreeze Polypeptide
Advanced Materials, EarlyView.Simple and inexpensive polypeptides composed of random copolymers of alanine and glutamic acid are effective antifreezes for applications in foods and biomedicine. The polypeptides, inspired by natural extremophile proteins, inhibit the growth of large ice crystals and prevent damage to sensitive biologics.
Thomas J. McPartlon +5 more
wiley +1 more source
Angewandte Chemie, EarlyView.Isotactic poly(cyclohexene carbonate) crystalizes both as enantiopure polymer and upon stereocomplexation of the two opposite enantiomers. Both structures are characterized by multiple H‐‐‐O═C tight attractive interactions, whereas in the stereocomplex a tight interdigitation of the two enantiomeric chains occurs due to additional intimate dipole ...
Massimo Christian D'Alterio +5 more
wiley +2 more sources
Molecules, 2019 Phyllanthus orbicularis (Phyllanthaceae) is an endemic evergreen tropical plant of Cuba that grows in the western part of the island and is used in traditional medicine as an infusion.
Antonio Francioso +8 more
doaj +1 more source
Advanced Materials, Volume 37, Issue 13, April 2, 2025.Metal‐covalent organic frameworks (MCOFs) are novel porous materials that exhibit the advantages of covalent and metal‐organic frameworks. However, it is extremely difficult to resolve their atomic structure and better understand their structure‐properties relation. This work utilizes a synergistic combination of advanced microscopy, spectroscopic, and
Seán Hennessey +11 more
wiley +1 more source
P450 Enzyme LyoI Performs Hydro‐2,2′‐Bifuran Oxidation in the Polyether Ionophore Lysocellin
Angewandte Chemie, EarlyView.In a study of the biosynthesis of the polyether ionophore lysocellin, the P450 enzyme LyoI was found to catalyze a rare oxidation of a hydro‐2,2′‐bifuran moiety to its hemiketal form. The oxidation was identified as the key for unlocking the bioactivity of lysocellin.
Michelle H. Rasmussen +4 more
wiley +2 more sources
Focus on chirality of HIV-1 non-nucleoside reverse transcriptase inhibitors [PDF]
, 2016 Chiral HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are of great interest since one enantiomer is often more potent than the corresponding counterpart against the HIV-1 wild type (WT) and the HIV-1 drug resistant mutant strains.
Famiglini, Valeria, Silvestri, Romano
core +2 more sources
Confirmation of the stereochemistry of spiroviolene
Beilstein Journal of Organic Chemistry, 2023 We confirm the previously revised stereochemistry of spiroviolene by X-ray crystallographically characterizing a hydrazone derivative of 9-oxospiroviolane, which is synthesized by hydroboration/oxidation of spiroviolene followed by oxidation of the resultant hydroxy group.
Yao Kong +9 more
openaire +3 more sources
Advanced Materials, EarlyView.Detecting proteins secreted by a single cell while retaining its viability remains challenging. A particles‐in‐particle (PiPs) system made by co‐encapsulating barcoded microparticles (BMPs) with a single cell inside an alginate hydrogel particle is introduced.
Félix Lussier +10 more
wiley +1 more source
Synthesis and Application of Bioactive N‐Functionalized Aziridines
Angewandte Chemie, EarlyView.This review discusses modern synthetic methods for the preparation of aziridine‐containing small molecules, including biocatalytic, electrocatalytic, and photocatalytic strategies. We highlight the compatibility of various synthetic methods with control of the exocyclic N‐substituent.
Hao Tan +4 more
wiley +2 more sources
Journal of Lipid Research, 2006 Ceramide is a component of the sphingomyelin cycle and a well-established lipid signaling molecule. We recently reported that ceramide specifically increased ABCA1-mediated cholesterol efflux to apolipoprotein A-I (apoA-I), a critical process that leads ...
Amy B. Ghering, W. Sean Davidson
doaj +1 more source