Results 71 to 80 of about 174,911 (284)

Cannabis through the looking glass: chemo- and enantio-selective separation of phytocannabinoids by enantioselective ultra high performance supercritical fluid chromatography [PDF]

, 2017
By using the Inverted Chirality Columns Approach (ICCA) we have developed an enantioselective UHPSFC method to determine the enantiomeric excess (ee) of (-)-Δ(9)-THC in medicinal marijuana (Bedrocan®).
Cavazzini, A, D'Acquarica, I, Gasparrini, F., Ismail, O, Manzo, C, Mazzoccanti, G, Villani, C, Wilcox, M   +7 more
core   +2 more sources

Absolute Stereochemistry of Ulapualide A. [PDF]

ChemInform, 2004
[structure: see text] The structure of ulapualide A (1) has been solved by X-ray crystallography in a complex with G-actin. The stereochemical configuration was assigned as 3S,9S,22S,23R,24S,26S,27S,31R,32R,33R.
Gerard Marriott, Ivan Rayment, John S. Allingham, Junichi Tanaka   +3 more
openaire   +4 more sources

Five-membered ring annelation in [2.2]paracyclophanes by aldol condensation

Beilstein Journal of Organic Chemistry, 2014
Under basic conditions 4,5,12,13-tetraacetyl[2.2]paracyclophane (9) cyclizes by a double aldol condensation to provide the two aldols 12 and 15 in a 3:7 ratio.
Henning Hopf, Swaminathan Vijay Narayanan, Peter G. Jones   +2 more
doaj   +1 more source

Further studies on the substrate spectrum of phytanoyl-CoA hydroxylase

Journal of Lipid Research, 2003
Refsum disease is a peroxisomal disorder characterized by adult-onset retinitis pigmentosa, anosmia, sensory neuropathy, ataxia, and an accumulation of phytanic acid in plasma and tissues.
Veerle Foulon, Stanny Asselberghs, Wendy Geens, Guy P. Mannaerts, Minne Casteels, Paul P. Van Veldhoven   +5 more
doaj   +1 more source

Synthesis and Structure-Activity Relationships of Novel Ecdysteroid Dioxolanes as MDR Modulators in Cancer

Molecules, 2013
Ecdysteroids, molting hormones of insects, can exert several mild, non-hormonal bioactivities in mammals, including humans. In a previous study, we have found a significant effect of certain derivatives on the ABCB1 transporter mediated multi-drug ...
Ana Martins, József Csábi, Attila Balázs, Diána Kitka, Leonard Amaral, József Molnár, András Simon, Gábor Tóth, Attila Hunyadi   +8 more
doaj   +1 more source

Enantioselective PCCP Brønsted acid-catalyzed aza-Piancatelli rearrangement. [PDF]

, 2019
An enantioselective aza-Piancatelli rearrangement has been developed using a chiral Brønsted acid based on pentacarboxycyclopentadiene (PCCP). This reaction provides rapid access to valuable chiral 4-amino-2-cyclopentenone building blocks from readily ...
Delgado, Jose M, Hammersley, Gabrielle R, Nichol, Meghan F, Read de Alaniz, Javier, Steffens, Helena C, Veits, Gesine K   +5 more
core  

Highly efficient synthesis of the tricyclic core of Taxol by cascade metathesis [PDF]

, 2014
An efficient enantioselective synthesis of the ABC tricyclic core of the anticancer drug Taxol is reported. The key step of this synthesis is a cascade metathesis reaction, which leads in one operation to the required tricycle if appropriate fine-tuning ...
Aldegunde M. J., Aldegunde M. J., Aldegunde M. J., Aurélien Letort, Bourgeois D., Bourgeois D., Bourgeois D., Bourgeois D., Bourgeois D., Chatterjee A. K., Cong Ma, De-Liang Long, Doi T., Garber S. B., Goldring P. D., Grieco P. A., Holton R. A., Holton R. A., Joëlle Prunet, Kim S.-H., Ma C., Masters J. J., Mendoza A., Morihara K., Mukaiyama T., Muller B., Muller B., Nicolaou K. C., Rémi Aouzal, Schiltz S., Scholl M., Schwab P., Swindell C. S., Wender P. A., Wender P. A., Wilde N. C., Winkler J. D., Yamazaki Y., Yared J. A., Yvon D.   +39 more
core   +3 more sources

Complete Stereochemistry of Tetrafibricin [PDF]

Organic Letters, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
Yoshito Kishi, Yoshihisa Kobayashi, Werngard Czechtizky   +2 more
openaire   +4 more sources

Crystal structure of 9-methacryloylanthracene

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C18H14O, with systematic name 1-(anthracen-9-yl)-2-methylprop-2-en-1-one, the ketonic C atom lies 0.2030 (16) Å out of the anthryl-ring-system plane. The dihedral angle between the planes of the anthryl and methacryloyl moieties is
Aditya Agrahari, Patrick O. Wagers, Steven M. Schildcrout, John Masnovi, Wiley J. Youngs   +4 more
doaj   +1 more source

Iron-mediated Preparation of Vinylcyclopropanes. Scope, Mechanism, and Applications [PDF]

, 2003
The addition of stabilized carbon nucleophiles to tricarbonyl(1-methoxycarbonylpentadienyl)iron(1+) cation (1a) proceeds via attack at C2 on the face of the ligand opposite the Fe(CO)3 group to generate tricarbonyl(pentenediyl)iron complexes 2. Oxidation
Cao, Yeyu, Donaldson, William A., Godula, Kamil, Yun, Young K.   +3 more
core   +1 more source