Results 71 to 80 of about 138,145 (310)

ZZE-Configuration of chromophore ß-153 in C-phycocyanin from Mastigocladus laminosus [PDF]

, 1987
The photochemistry of C-phycocyanin has been studied after denaturation in the dark. It shows an irreversible reaction which has characteristics of a Ζ,Ζ,Ε- to Z,Z,Z-isomerization of dihydrobilins. Its amplitude depends on the reaction conditions, with
Bode, W., Fischer, R., Huber, R., Rüdiger, W., Scheer, Hugo, Schirmer, T., Schmidt, G., Siebzehnrübl, S.   +7 more
core   +1 more source

Beyond Traditional RAFT Polymerization: Emerging Strategies and Future Perspectives; A Third Update

Advanced Science, EarlyView.
This review explores recent advances in the past five years for non‐traditional RAFT polymerization, focusing on new activation strategies, sustainable depolymerization, and integration with automated and AI‐driven synthesis. Together, these innovations advance polymer chemistry and reveal how the pieces of the non‐traditional RAFT puzzle are steadily ...
Vianna F. Jafari, James L. Grace, Jiajia Li, Joji Tanaka, Glen R. Jones, Athina Anastasaki, Wei You, Jian Zhu, Masami Kamigaito, Cyrille Boyer, Greg G. Qiao   +10 more
wiley   +1 more source

Stereodivergent Synthesis of Three Contiguous Stereogenic Centers by Cu/Ir‐Catalyzed Borylallylation

Angewandte Chemie, EarlyView.
An alkene borylallylation strategy enabled by cooperative Cu/Ir‐catalysis has been uncovered for accessing three contiguous stereogenic centres. This strategy is notable given the inherent challenges of constructing molecules with multiple stereocenters while maintaining high selectivity bearing diverse functional groups.
Suman Das, Stanna K. Dorn, M. Kevin Brown   +2 more
wiley   +2 more sources

Iron-mediated Preparation of Vinylcyclopropanes. Scope, Mechanism, and Applications [PDF]

, 2003
The addition of stabilized carbon nucleophiles to tricarbonyl(1-methoxycarbonylpentadienyl)iron(1+) cation (1a) proceeds via attack at C2 on the face of the ligand opposite the Fe(CO)3 group to generate tricarbonyl(pentenediyl)iron complexes 2. Oxidation
Cao, Yeyu, Donaldson, William A., Godula, Kamil, Yun, Young K.   +3 more
core   +1 more source

Synthesis of cyclopropyl-substituted furans by Brønsted acid promoted cascade reactions [PDF]

, 2015
Chloroacetic acid promotes an efficient and diastereoselective intramolecular cascade reaction of electron-deficient ynenones to deliver products featuring a 2,3,5-trisubstituted furan bearing a fused cyclopropyl substituent at the 5-position ...
Achmatowicz, Albrecht, Barluenga, Benary, Boto, Casey, Ciufolini, Clark, Corma, Csuk, Csuk, Donaldson, Donohoe, Fedoryński, Feist, Fritz, Gandini, Gilchrist, González, González, Hashmi, Hou, Högberg, Jung, Knorr, Kobayashi, Krasnaya, Kuroda, Lebel, Li, Li, Lipshutz, Ma, MacMillan, Paal, Pellissier, Ripaud, Sperry, Vicente, Wang, Wessjohann, Wipf, Wu, Xia, Yang, Zhang, Zimmerman   +46 more
core   +2 more sources

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

Chemical Synthesis of Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii Capsular Polysaccharide Fragments as Leads for Cross‐Protection

Angewandte Chemie, EarlyView.
A total of 16 chemically synthesized capsular polysaccharide (CPS) fragments related to Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii were analyzed by glycan microarray. Comparative screening revealed three conserved epitopes that act as cross‐protective vaccine lead candidates against multidrug‐resistant (MDR) bacterial ...
Amar Kumar Mishra, Emelie E. Reuber, Diksha Rai, Leif E. Sander, Julia Duerr, Simon Y. Graeber, Marcus A. Mall, Bettina C. Fries, Peter H. Seeberger, Suvarn S. Kulkarni   +9 more
wiley   +2 more sources

A Comparative Study on Interactions of Antimicrobial Peptides L- and D-phenylseptin with 1,2-dimyristoyl-sn-glycero-3-phosphocholine

Applied Sciences, 2019
L-phenylseptin (L-Phes) and D-phenylseptin (D-Phes) are amphibian antimicrobial peptides isolated from the skin secretion of Hypsiboas punctatus. In the N-termini, L-Phes and D-Phes contain three consecutive phenylalanine residues, l-Phe-l-Phe-l-Phe and ...
Batsaikhan Mijiddorj, Yuta Matsuo, Hisako Sato, Kazuyoshi Ueda, Izuru Kawamura   +4 more
doaj   +1 more source

[1,3]/[1,4]-Sulfur atom migration in β-hydroxyalkylphosphine sulfides

Beilstein Journal of Organic Chemistry, 2020
β-Hydroxyalkylphosphine sulfides undergo [1,3]- or [1,4]-sulfur atom phosphorus-to-carbon migration in the presence of Lewis or Brønsted acids. The direction of sulfur atom migration depends on the type of acid used for the reaction. In the presence of a
Katarzyna Włodarczyk, Piotr Borowski, Marek Stankevič   +2 more
doaj   +1 more source

On the prevalence of bridged macrocyclic pyrroloindolines formed in regiodivergent alkylations of tryptophan. [PDF]

, 2016
A Friedel-Crafts alkylation is described that efficiently transforms tryptophan-containing peptides into macrocycles of varying ring connectivity. Factors are surveyed that influence the distribution of regioisomers, with a focus on indole C3-alkylations
Curtin, Brice H, Harran, Patrick G, Houk, KN, Lawson, Kenneth V, Rose, Tristin E, Simon, Adam   +5 more
core   +1 more source