Angewandte Chemie, EarlyView.A radical cascade process involving the activation of two aliphatic C–H bonds in a series of five elementary steps converts readily available terminal alkynes into functionalized cyclopentylmethyl arylsulfones. The methodology delivers flexible synthetic intermediates and was applied to the preparation of diquinanes and triquinanes possessing a rare ...
Lise Benoist +4 more
wiley +2 more sources
Organotin(IV) Dithiocarbamate Complexes: Chemistry and Biological Activity
Molecules, 2018 Significant attention has been given to organotin(IV) dithiocabamate compounds in recent times. This is due to their ability to stabilize specific stereochemistry in their complexes, and their diverse application in agriculture, biology, catalysis and as
Jerry O. Adeyemi, Damian C. Onwudiwe
doaj +1 more source
On the mechanism of Dehydroquinate synthase : a thesis presented to Massey University in partial fulfilment of the requirements for the degree of Master of Science in Chemistry [PDF]
, 2001 The aim of this thesis is to investigate the influence of fluorine substitution on the second reaction of the shikimate pathway catalysed by the enzyme 3-dehydroquinate synthase.
Kathirgamanathan, Kalyani
core
Copper‐Catalyzed Three‐Component Selective 1,4‐Amino Oxygenation of 1,3‐Dienes
Angewandte Chemie, EarlyView.Enclosed is a copper‐catalyzed selective 1,4‐amino oxgenation of 1,3‐dienes with the presence of a strong Brønsted acid. This three‐component transformation offers a novel and powerful approach to construct (E)‐1,4‐allylic amino oxygenated motifs by the simultaneous installation of structurally diverse alkylamines and alcohols directly onto 1,3‐dienes.
Guangshou Feng +2 more
wiley +2 more sources
MNDO Study of Nitrogen Atom Inversion in Piperazine, N,N'-Dimethylpiperazine and N,N'-Dichloropiperazine [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 1997 MNDO semi-empirical SCF MO calculations are used to study the pyramidal nitrogen atom inversion and configurational equilibria in the title compounds.
Issa Yavari +3 more
doaj
Mechanism-based Enzyme Inactivators of Phytosterol Biosynthesis
Molecules, 2004 Current progress on the mechanism and substrate recognition by sterol methyl transferase (SMT), the role of mechanism-based inactivators, other inhibitors of SMT action to probe catalysis and phytosterol synthesis is reported.
W. David Nes +8 more
doaj +1 more source
Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis. [PDF]
, 2016 The use of photochemical transformations is a powerful strategy that allows for the formation of a high degree of molecular complexity from relatively simple building blocks in a single step. A central feature of all light-promoted transformations is the
Kärkäs, Markus D. +2 more
core +2 more sources
Angewandte Chemie, EarlyView.Nonheme Fe enzyme isopenicillin N synthase was reprogrammed and evolved as an efficient nitrogen migratase IPNSNim, converting diverse azanyl esters to valuable l‐arylglycines with up to 16 000 TTN and 97:3 e.r. IPNSNim and ACCONim allowed enantiodivergent preparation of both l‐ and d‐arylglycines.
Ken Lin +7 more
wiley +2 more sources
Genomics-inspired discovery of massiliachelin, an agrochelin epimer from Massilia sp. NR 4-1
Beilstein Journal of Organic Chemistry, 2019 A putative siderophore locus was detected in the genome of the violacein-producing bacterium Massilia sp. NR 4-1 and predicted to direct the biosynthesis of a molecule that is structurally related to the thiazoline-containing siderophore micacocidin.
Jan Diettrich +2 more
doaj +1 more source
Enantioselective synthesis of non-proteinogenic 2-arylallyl-α-amino acids via Pd/In catalytic cascades [PDF]
, 2006 An efficient synthesis of both R- and S-enantiomers of 2-arylallyl-α-amino acids via a diastereoselective Pd/In mediated catalytic allylation of chiral N-sulfinyl-α-imino esters is described.
Anwar +23 more
core +1 more source