General amyloid inhibitors? A critical examination of the inhibition of IAPP amyloid formation by inositol stereoisomers. [PDF]
, 2014 Islet amyloid polypeptide (IAPP or amylin) forms amyloid deposits in the islets of Langerhans; a process that is believed to contribute to the progression of type 2 diabetes and to the failure of islet transplants.
Raleigh, David, Wang, Hui
core +2 more sources
Five-membered ring annelation in [2.2]paracyclophanes by aldol condensation
Beilstein Journal of Organic Chemistry, 2014 Under basic conditions 4,5,12,13-tetraacetyl[2.2]paracyclophane (9) cyclizes by a double aldol condensation to provide the two aldols 12 and 15 in a 3:7 ratio.
Henning Hopf +2 more
doaj +1 more source
Total synthesis of aurofusarin: studies on the atropisomeric stability of bis-naphthoquinones [PDF]
, 2018 An efficient annulation involving pyrone addition to a quinone and Dieckmann condensation was developed for rapid assembly of a γ-naphthopyrone monomeric precursor to the bis-naphthoquinone natural product aurofusarin.
Allen +42 more
core +1 more source
DESIGN OF AN EDUCATIONAL GAME AND ITS USE IN A TEAM GAME TOURNAMENT AS A STRATEGY TO ENGAGE STUDENTS IN REVIEWING STEREOCHEMISTRY CONCEPTS [PDF]
Química NovaThis paper presents a Chemistry Team Game Tournament (TGT) as a didactic strategy to review stereochemistry concepts. For this purpose, a multilingual (English, Italian, French, and Portuguese) educational game, Stereochemistry Race, was developed on the
José Nunes da Silva Júnior +8 more
doaj +1 more source
High resolution mass spectrometry in molecular structure and stereochemical studies - Effect of stereochemistry on the fragmentation of epimeric derivatives of azabicycloalkanes [PDF]
High resolution mass spectrometry in studies of stereochemistry effect on fragmentation of epimeric derivatives of ...
Burlingame, A. L. +2 more
core +1 more source
Enantioselective Synthesis of 5-epi-Citreoviral Using Ruthenium-Catalyzed Asymmetric Ring-Closing Metathesis [PDF]
, 2009 Chiral ruthenium olefin metathesis catalysts can perform asymmetric ring-closing reactions in ≥90% ee with low catalyst loadings. To illustrate the practicality of these reactions and the products they form, an enantioselective total synthesis of 5-epi ...
Funk, Timothy W.
core +2 more sources
Synthesis of cyclopropyl-substituted furans by Brønsted acid promoted cascade reactions [PDF]
, 2015 Chloroacetic acid promotes an efficient and diastereoselective intramolecular cascade reaction of electron-deficient ynenones to deliver products featuring a 2,3,5-trisubstituted furan bearing a fused cyclopropyl substituent at the 5-position ...
Achmatowicz +46 more
core +2 more sources
, 2020 This short chapter is really just to set the scene for the rest of the book, highlighting the importance of stereochemistry and the approaches we can use to study the topic. Don't worry if the new material appears daunting at this point. We'll go through it slowly in the relevant chapters.
+4 more sources
Detection of substrate binding motifs for morphine biosynthetic pathway intermediates in novel wound inducible (R,S)-reticuline 7-O-methyltransferase of Papaver somniferum [PDF]
, 2011 The benzylisoquinoline alkaloids (BIA) comprise a large and diverse group of nitrogen-containing secondary metabolites with about 2500 compounds identified in plants.
Abha Meena +5 more
core +2 more sources
Environmental Science and Technology, 2013 In this study, the systemic assessments of the stereoisomers of triazole fungicide difenoconazole are reported for the first time, including absolute stereochemistry, stereoselective bioactivity toward pathogens (Alternaria sonali, Fulvia fulva, Botrytis
F. Dong +11 more
semanticscholar +1 more source