Results 111 to 120 of about 17,928 (220)
A platform approach to the affinity capture and enrichment of host cell proteins to enable their subsequent deep characterization and elucidation of variants or proteoforms (e.g., molecular size variants, charge variants, glycoforms, etc.). ABSTRACT Removing host cell proteins (HCPs) during biotherapeutic manufacturing is essential to ensure patient ...
Michael E. Dolan +6 more
wiley +1 more source
Marine polyhydroxylated macrolides’ drug discovery potential is limited by structural complexity and scarce material supply, hindering structure assignment, synthesis, and biological studies. Here, we present an integrated workflow that combines chemogenomic profiling, ultra‐high‐resolution NMR‐guided structural revision and stereochemical assignment ...
Malcolm R. P. George +9 more
wiley +2 more sources
This study focused on Artemisia selengensis leaves (ASL), a discarded agricultural waste. 72 compounds were identified by UPLC‐Q‐TOF‐MS. “Green” extraction with DES was optimized, and ASL's XO—inhibition was explored, presenting new ways for waste utilization. ABSTRACT Artemisia selengensis is a medicinal and edible plant, whose tender stems are widely
Lixia Li +8 more
wiley +1 more source
Mass spectra of stereoisomers of 1-substituted quinolizidin-1-ol derivatives.
Hidetoshi Fujiwara
openalex +2 more sources
Isopod feces–mediated shifts in germination timing enhance seedling establishment
Summary Seedlings are particularly vulnerable to herbivory because their defenses are underdeveloped and their capacity to tolerate damage is limited. However, how seedlings cope with such threats remains poorly understood. Animal feces may provide important chemical cues that influence plant responses to herbivory.
Akira Yamawo +10 more
wiley +1 more source
The Polytope Formalism: application to molecular constitution and the prospect of a complete description of Chemical Space. [PDF]
Canfield PJ, Crossley MJ.
europepmc +1 more source
Enhanced Solubility and Deprotection of Pyrene-4,5,9,10-tetraones through Propylene Glycol and Propanediol Protection. [PDF]
Wessling R +5 more
europepmc +1 more source
We develop new bifacial chiral non‐fullerene acceptors (NFAs) for organic solar cells (OSCs). Through comparative investigations of four NFAs including meso, racemic, and chiral entries, we demonstrate the superiority of homochiral NFAs for the first time.
Shuang Li +4 more
wiley +2 more sources
Rigorous treatment of polytopal rearrangements reveal surprising complexity of stereoisomerism configuration landscapes. [PDF]
Canfield PJ, Crossley MJ.
europepmc +1 more source

