Results 111 to 120 of about 17,928 (220)

Elucidation of Proteoforms of Chinese Hamster Ovary (CHO) Phospholipase B‐Like 2 (PLBL2) Captured From a Monoclonal Antibody

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 2, Page 406-419, February 2026.
A platform approach to the affinity capture and enrichment of host cell proteins to enable their subsequent deep characterization and elucidation of variants or proteoforms (e.g., molecular size variants, charge variants, glycoforms, etc.). ABSTRACT Removing host cell proteins (HCPs) during biotherapeutic manufacturing is essential to ensure patient ...
Michael E. Dolan   +6 more
wiley   +1 more source

Caylobolide B: Structure Revision, Total Synthesis, Biological Characterization, and Discovery of New Analogues

open access: yesAngewandte Chemie, Volume 138, Issue 4, 22 January 2026.
Marine polyhydroxylated macrolides’ drug discovery potential is limited by structural complexity and scarce material supply, hindering structure assignment, synthesis, and biological studies. Here, we present an integrated workflow that combines chemogenomic profiling, ultra‐high‐resolution NMR‐guided structural revision and stereochemical assignment ...
Malcolm R. P. George   +9 more
wiley   +2 more sources

Artemisia selengensis Leaves, a Vegetable Waste: LC‐MS‐Based Chemical Profiling, Ultrasound‐Assisted DES Extraction, and Xanthine Oxidase Inhibitory Activity

open access: yeseFood, Volume 7, Issue 1, February 2026.
This study focused on Artemisia selengensis leaves (ASL), a discarded agricultural waste. 72 compounds were identified by UPLC‐Q‐TOF‐MS. “Green” extraction with DES was optimized, and ASL's XO—inhibition was explored, presenting new ways for waste utilization. ABSTRACT Artemisia selengensis is a medicinal and edible plant, whose tender stems are widely
Lixia Li   +8 more
wiley   +1 more source

Isopod feces–mediated shifts in germination timing enhance seedling establishment

open access: yesNew Phytologist, Volume 249, Issue 4, Page 1909-1919, February 2026.
Summary Seedlings are particularly vulnerable to herbivory because their defenses are underdeveloped and their capacity to tolerate damage is limited. However, how seedlings cope with such threats remains poorly understood. Animal feces may provide important chemical cues that influence plant responses to herbivory.
Akira Yamawo   +10 more
wiley   +1 more source

Chiral Bifacial Non‐Fullerene Acceptors with Chirality‐Induced Spin Selectivity: A Homochiral Strategy to Improve Organic Solar Cell Performance

open access: yesAngewandte Chemie, Volume 138, Issue 3, 16 January 2026.
We develop new bifacial chiral non‐fullerene acceptors (NFAs) for organic solar cells (OSCs). Through comparative investigations of four NFAs including meso, racemic, and chiral entries, we demonstrate the superiority of homochiral NFAs for the first time.
Shuang Li   +4 more
wiley   +2 more sources

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