Results 21 to 30 of about 14,256 (222)
Stereoselective Radical Translocations
CHIMIA, 2008 The stereochemical outcome of intramolecular radical mediated hydrogen transfer (= radical translocation) is discussed. Low to excellent levels of stereocontrol are observed making such processes attractive for applications in target-oriented synthesis.
Philippe Renaud +5 more
openaire +5 more sources
Molecules, 2022 Herein the reaction mechanism and the origin of stereoselectivity of asymmetric hydrogenation of oximes to hydroxylamines catalyzed by the cyclometalated iridium (III) complexes with chiral substituted single cyclopentadienyl ligands (Ir catalysts A1 and
Qaim Ali +6 more
doaj +1 more source
Synthesis of Glycosides of Glucuronic, Galacturonic and Mannuronic Acids: An Overview
Molecules, 2011 Uronic acids are carbohydrates present in relevant biologically active compounds. Most of the latter are glycosides or oligosaccharides linked by their anomeric carbon, so their synthesis requires glycoside-bond formation. The activation of this anomeric
José Kovensky, Anne Wadouachi
doaj +1 more source
Molecules, 2023 Pioglitazone, a PPAR-gamma activator used to diagnose hyperglycemia, was studied for its stereoselective deposition and active enantiomers in female albino Wistar rats.
Tatineni Spandana +8 more
doaj +1 more source
Angewandte Chemie, EarlyView.Manganese‐catalyzed enantioselective C(sp3)─H lactonization with hydrogen peroxide enables the direct desymmetrization of malonic monoesters and malonic acids, providing highly enantioenriched γ‐ and δ‐lactones (up to >99% ee) ABSTRACT Malonate derivatives are readily available starting materials widely employed in the synthesis of bioactive compounds.
Nikos Siakavaras +3 more
wiley +2 more sources
Chemical Proteomics Identifies Ketogenesis‐Mediated Cysteine Modifications Regulating Redox Function
Angewandte Chemie, EarlyView.Herein, we report ketone body induce cysteine modifications beyond lysine acylation, as revealed by integrating chemical proteomics with open‐search methods. Among the modifications, cysteine crotonation (Ccr) was chemically validated by endogenous peptide‐based co‐elution assays.
Yuan‐Fei Zhou +8 more
wiley +2 more sources
Diastereo- and enantioselective preparation of cyclopropanol derivatives
Beilstein Journal of Organic Chemistry, 2019 The diastereoselective carbocupration reaction of alkoxy-functionalized cyclopropene derivatives, followed by a subsequent trapping of the resulting cyclopropylmetal species with an electrophilic source of oxygen (oxenoid) afforded various ...
Marwan Simaan, Ilan Marek
doaj +1 more source
Elucidating the Stereodirecting Effect of C‐4 Acyl Groups on Galactosyl Donors
Angewandte Chemie, EarlyView.Tipping the balance of the reaction coordinate by changing a single protecting group. We demonstrate that α‐ and β‐galactosyl triflates are formed during galactosylation reactions and likely glycosylate according to a Curtin–Hammett scenario. C‐4 acyl groups exert their stereodirecting effect by sterically blocking displacement of α‐galactosyl ...
Floor ter Braak +8 more
wiley +2 more sources
(Z)-Selective Takai olefination of salicylaldehydes
Beilstein Journal of Organic Chemistry, 2017 The Takai olefination (or Takai reaction) is a method for the conversion of aldehydes to vinyl iodides, and has seen widespread implementation in organic synthesis. The reaction is usually noted for its high (E)-selectivity; however, herein we report the
Stephen M. Geddis +5 more
doaj +1 more source
Angewandte Chemie, EarlyView.Chiral cyclopropenimine–thiourea organocatalysts enabled both high reactivity and precise stereocontrol in the ring‐opening polymerization of rac‐lactide. The bifunctional system exhibited a TOF up to 1,710 h−1 with Pm = 0.90 at 25°C, and achieved Pm = 0.99 at −78°C while maintaining a TOF of 16.3 h−1.
Sumin Lee +8 more
wiley +2 more sources