Results 21 to 30 of about 11,587,644 (360)
Kinetics of the reaction of 5-substituted orotic acids with diazodiphenylmethane [PDF]
Journal of the Serbian Chemical Society, 2004 Rate konstants for the reaction of eight 5-substituted orotic acids with diazodiphenylmethane (DDM) in dimethylformamide (DMF) were determined at 30 ºC by the known spectrophotometricmethod.
Jovanović Bratislav Ž. +2 more
doaj +3 more sources
Molecules, 2001 Benzonorbornadiene 21, 7-spirocyclopropylbenzonorbornadiene 23, 7,7-dimethylbenzonorbornadiene 25, and 7-spirocyclopentylbenzonorbornadiene 27 have been reacted with 3,6-di(2-pyridyl)-s-tetrazine (rate: 21>23>25=27) to form symmetrical 4,5 ...
Peter A. Harrison, Ronald N. Warrener
doaj +1 more source
Transcriptome-Wide Off-Target Effects of Steric-Blocking Oligonucleotides
bioRxiv, 2020 Steric-blocking oligonucleotides (SBOs) are short, single-stranded nucleic acids designed to modulate gene expression by binding to mRNA and blocking access from cellular machinery such as splicing factors.
Erle M. Holgersen +17 more
semanticscholar +1 more source
Insights on tert-butyl alkylation effects on fluorobenzene
Scientific African, 2021 Directing effects of substituents on the benzene ring, ortho and para directors by electron donating groups and meta directors using electron withdrawing groups have been studied and reported widely. In particular and for many years, the directing effect
Lewis Mtashobya
doaj
Steric effects in induced-charge electro-osmosis for strong electric fields [PDF]
Phys. Rev. Fluids 8, 083702 (2023), 2023 We study the role of steric effects on the induced-charge electro-osmosis (ICEO) phenomenon using a recently developed mesoscale fluid model. A hybrid Eulerian-Lagrangian method is used to simulate the dynamics of discrete immersed ions in a thermally fluctuating solvent near a metallic plate embedded in the dielectric interface.
arxiv +1 more source
Does the Intra‐Atomic Deformation Energy of Interacting Quantum Atoms Represent Steric Energy?
ChemistryOpen, 2019 We show that the mutual, through‐space compression of atomic volume experienced by approaching topological atoms causes an exponential increase in the intra‐atomic energy of those atoms, regardless of approach orientation. This insight was obtained using
Benjamin C. B. Symons +4 more
doaj +1 more source
Strong-coupling theory of counterions with hard cores between symmetrically charged walls [PDF]
Physical Review E 102 (4), 042604 (2020), 2020 By a combination of Monte Carlo simulations and analytical calculations, we investigate the effective interactions between highly charged planar interfaces, neutralized by mobile counterions (salt-free system). While most previous analysis have focused on point-like counterions, we treat them as charged hard spheres.
arxiv +1 more source
Beilstein Journal of Organic Chemistry, 2011 A broad perspective of various factors influencing alkene selenenylation has been developed by concurrent detailed analysis of key experimental and theoretical data, such as asymmetric induction, stereochemistry, relative reactivities, and comparison ...
Vadim A. Soloshonok, Donna J. Nelson
doaj +1 more source
Molecules, 2023 A density functional theory (DFT) study combined with the steric maps of buried volume (%VBur) as molecular descriptors and an energy decomposition analysis through the ASM (activation strain model)–NEDA (natural energy decomposition analysis) approach ...
Olga D’Anania +2 more
doaj +1 more source
Bi-steric mTORC1 inhibitors induce apoptotic cell death in tumor models with hyperactivated mTORC1
The Journal of Clinical Investigation, 2023 The PI3K/AKT/mTOR pathway is commonly dysregulated in cancer. Rapalogs exhibit modest clinical benefit, likely owing to their lack of effects on 4EBP1. We hypothesized that bi-steric mTORC1-selective inhibitors would have greater potential for clinical ...
Heng Du +8 more
doaj +1 more source