Results 61 to 70 of about 264,880 (337)

Effect of grafting on the binding transition of two flexible polymers

, 2016
We investigate the binding transition of two flexible polymers grafted to a steric surface with closeby end points. While free polymers show a discontinuous transition, grafting to a steric flat surface leads to a continuous binding transition.
Janke, Wolfhard, Tholen, Katharina, Zierenberg, Johannes   +2 more
core   +1 more source

Size Dependence of Steric Shielding and Multivalency Effects for Globular Binding Inhibitors [PDF]

, 2015
Competitive binding inhibitors based on multivalent nanoparticles have shown great potential for preventing virus infections. However, general design principles of highly efficient inhibitors are lacking as the quantitative impact of factors such as ...
Böttcher, Christoph, Dernedde, Jens, Haag, Rainer, Kuehne, Christian, Liese, Susanne, Ludwig, Kai, Netz, Roland, Vonnemann, Jonathan   +7 more
core   +2 more sources

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

A combined "electrochemical-frustrated Lewis pair" approach to hydrogen activation: surface catalytic effects at platinum electrodes [PDF]

, 2014
Herein, we extend our “combined electrochemical–frustrated Lewis pair” approach to include Pt electrode surfaces for the first time. We found that the voltammetric response of an electrochemical–frustrated Lewis pair (FLP) system involving the B(C6F5)3 ...
Ashley, Ashley, Binding, Brown, Cauliez, Chapman, Chase, Chatgilialoglu, Compton, Croissant, de Leon, Duñach, Erker, Esteves, Fang, Farrell, Griller, Gritzner, Herrington, Holschumacher, Iwasita, Jutzi, Kolychev, Lawrence, Lawrence, Lawrence, LeSuer, Liu, Lu, Ma, Merino-Jiménez, Ménard, Mömming, Pedersen, Santos, Spies, Srivastava, Stephan, Stephan, Stephan, Stephan, Stephan, Sumerin, Tran, Travis, Welch, Welch, Whited, Zhang   +48 more
core   +2 more sources

The Immobilization of Hyaluronic Acid in 3D Hydrogel Scaffolds Modulates Macrophage Polarization

Advanced Biology, EarlyView.
This study explores the use of collagen‐hyaluronic acid (HA) hydrogels for the 3D culture of macrophages, providing a useful tool for modelling macrophage behavior in tissues and diseases. It highlights how hydrogel composition, mechanical properties, and preparation methods influence macrophage behavior, revealing for the first time that HA's ...
Tiah CL Oates, Jasmin Boyd, Louise Dolan, C de Kergariou, Jingwen Zhu, Ash Toye, Adam W Perriman, Asme Boussahel   +7 more
wiley   +1 more source

Resummed thermodynamic perturbation theory for bond cooperativity in associating fluids with small bond angles: Effects of steric hindrance and ring formation [PDF]

, 2014
In this paper we develop a thermodynamic perturbation theory for two site associating fluids which exhibit bond cooperativity. We include both steric hindrance and ring formation such that the equation of state is bond angle dependent.
Amin Haghmoradi, Bennett D. Marshall, Frenkel D., Walter G. Chapman   +3 more
core   +2 more sources

First‐Principles Modeling of Solid Solution Softening and Hardening Effects in Al–Mg–Zr–Si Aluminum Alloys

Advanced Engineering Materials, EarlyView.
The role of various alloying elements in face‐centered cubic aluminum on the barrier of a Shockley partial dislocation during its motion is presented. The study aims to understand how alloying atoms such as Mg, Si, and Zr affect the energy landscape for dislocation motion, thus influencing the solid solution hardening and softening in aluminum, which ...
Inna Plyushchay, Zhengqing Wei, Nebahat Bulut, Sibylle Gemming   +3 more
wiley   +1 more source

Ferrocenoyl-adenines: substituent effects on regioselective acylation

Beilstein Journal of Organic Chemistry, 2022
A series of N6-substituted adenine–ferrocene conjugates was prepared and the reaction mechanism underlying the synthesis was explored. The SN2-like reaction between ferrocenoyl chloride and adenine anions is a regioselective process in which the product ...
Mateja Toma, Gabrijel Zubčić, Jasmina Lapić, Senka Djaković, Davor Šakić, Valerije Vrček   +5 more
doaj   +1 more source

Steric Effects of Alkyl Ammonium Salts on the Combustion of Exchanged Smectite Clays [PDF]

, 2018
Bomb calorimetry was explored as a new method for determining the cation exchange capacity (CEC) of clays. Smectite clays were modified with several alkyl ammonium salts varying in number of carbons and the spatial orientation of the carbons about the ...
Keith, Celeste A.
core   +1 more source

Clustering of microswimmers: Interplay of shape and hydrodynamics

, 2018
The spatiotemporal dynamics in systems of active self-propelled particles is controlled by the propulsion mechanism in combination with various direct interactions, such as steric repulsion, hydrodynamics, and chemical fields.
Gompper, Gerhard, Qi, Kai, Theers, Mario, Westphal, Elmar, Winkler, Roland G.   +4 more
core   +1 more source