Results 51 to 60 of about 890,702 (316)

The Use of Chinese Yang/Qi-Invigorating Tonic Botanical Drugs/Herbal Formulations in Ameliorating Chronic Kidney Disease by Enhancing Mitochondrial Function

open access: yesFrontiers in Pharmacology, 2021
Background: Chronic kidney disease (CKD) is a leading cause of morbidity and mortality. Mitochondrial dysfunction has been implicated as a key factor in the development of CKD.
Jiayi Tian   +12 more
doaj   +1 more source

Complications of percutaneous endoscopic gastrostomy in dogs and cats receiving corticosteroid treatment [PDF]

open access: yes, 2016
BACKGROUND: Corticosteroid treatment is commonly required in veterinary patients for treatment of inflammatory, immune‐mediated, neurologic, and neoplastic diseases, which also may require assisted enteral nutrition via percutaneous endoscopic ...
Aguiar, J, Chang, Y M, Garden, O A
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Protection of HT22 neuronal cells against chemically-induced ferroptosis by catechol estrogens: protein disulfide isomerase as a mechanistic target

open access: yesScientific Reports
Ferroptosis is a form of regulated cell death, characterized by excessive iron-dependent lipid peroxidation. Biochemically, ferroptosis can be selectively induced by erastin through glutathione depletion or through inhibition of glutathione peroxidase 4 ...
Xuanqi Huang, Ming-Jie Hou, Bao Ting Zhu
doaj   +1 more source

Coffee intake leads to preeclampsia-like syndromes in susceptible pregnant rats

open access: yesJournal of Nutritional Science
Coffee is one of the most popular beverages worldwide, and there is an increasing concern of the health risk of coffee consumption in pregnancy. Preeclampsia (PE) is a serious pregnancy disease that causes elevated blood pressure and proteinuria in ...
Linyan Chen, Yi Duan, Pan Wang
doaj   +1 more source

ADHD symptoms and use of anabolic androgenic steroids among male weightlifters

open access: yesScientific Reports, 2022
Use of anabolic androgenic steroids (AAS) is associated with adverse health effects. The factors that predispose to AAS use among athletes are poorly understood, but attention deficit/hyperactivity disorder (ADHD), which is known to occur among athletes ...
Emilie Kildal   +2 more
doaj   +1 more source

Influence of operating parameters on the biodegradation of steroid estrogens and nonylphenolic compounds during biological wastewater treatment processes [PDF]

open access: yes, 2009
This document is the unedited author's version of a Submitted Work that was subsequently accepted for publication in Environmental Science & Technology, copyright © American Chemical Society after peer review.
Ahel M.   +55 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Cholesterol sulfate in human physiology: what's it all about?

open access: yesJournal of Lipid Research, 2003
Cholesterol sulfate is quantitatively the most important known sterol sulfate in human plasma, where it is present in a concentration that overlaps that of the other abundant circulating steroid sulfate, dehydroepiandrosterone (DHEA) sulfate.
Charles A. Strott, Yuko Higashi
doaj   +1 more source

The Anabolic Androgenic Steroid Treatment Gap: A National Study of Substance Use Disorder Treatment

open access: yesSubstance Abuse: Research and Treatment, 2020
Background: Anabolic androgenic steroid (AAS) use is associated with serious mental and physical health problems. Evidence indicates that AAS use among people who use psychoactive substances is higher than in the general population.
Ingrid Amalia Havnes   +4 more
doaj   +1 more source

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