Results 1 to 10 of about 192,167 (361)

Impact of TR₃₄/L98H, TR₄₆/Y121F/T289A and TR₅₃ Alterations in Azole-Resistant Aspergillus fumigatus on Sterol Composition and Modifications after In Vitro Exposure to Itraconazole and Voriconazole [PDF]

Microorganisms, 2022
Background: Sterols are the main components of fungal membranes. Inhibiting their biosynthesis is the mode of action of azole antifungal drugs that are widely used to treat fungal disease including aspergillosis.
Rose-Anne Lavergne, Marjorie Albassier, Jean-Benoît Hardouin, Carlos Alvarez-Moreno, Fabrice Pagniez, Florent Morio, Patrice Le Pape, Isabelle Ourliac-Garnier   +7 more
doaj   +2 more sources

Exploration of Hypolipidemic Effects of Sterols from Pleurotus tuber-regium(Fr.) Sing Sclerotium [PDF]

Foods
The extraction technology of sterol was confirmed by ethanol reflux and saponification in this study. The orthogonal test was employed to assess the impact of extraction time, solid–liquid ratio, ethanol concentration and extraction temperature on the ...
Chao Wang, Yuan Liu, Yuting Duan, Haiping Lin   +3 more
doaj   +2 more sources

Chemical Analysis of Composition of Raw Soybean Oil Deodorized Distillates by GC-MS [PDF]

Pizhūhish va Nuāvarī dar ̒Ulūm va Sanāyi̒-i Ghaz̠āyī, 2021
Deodorizer distillate is regarded as a waste material of the edible oil industries. It has intricate nature that consists of a valuable source of bioactive and nutritive compounds including phytosterols, tocopherols and squalene that are valuable ...
Parisa Jafarian Asl, Razieh Niazmand, Moslem Jahani   +2 more
doaj   +1 more source

Unexpected Role of Sterol Synthesis in RNA Stability and Translation in Leishmania

Biomedicines, 2021
Leishmania parasites are trypanosomatid protozoans that cause leishmaniasis affecting millions of people worldwide. Sterols are important components of the plasma and organellar membranes.
Zemfira N. Karamysheva, Samrat Moitra, Andrea Perez, Sumit Mukherjee, Elena B. Tikhonova, Andrey L. Karamyshev, Kai Zhang   +6 more
doaj   +1 more source

A Comprehensive In Silico Study of New Metabolites from Heteroxenia fuscescens with SARS-CoV-2 Inhibitory Activity

Molecules, 2022
Chemical investigation of the total extract of the Egyptian soft coral Heteroxenia fuscescens, led to the isolation of eight compounds, including two new metabolites, sesquiterpene fusceterpene A (1) and a sterol fuscesterol A (4), along with six known ...
Fahd M. Abdelkarem, Alaa M. Nafady, Ahmed E. Allam, Mahmoud A. H. Mostafa, Rwaida A. Al Haidari, Heba Ali Hassan, Magdi E. A. Zaki, Hamdy K. Assaf, Mohamed R. Kamel, Sabry A. H. Zidan, Ahmed M. Sayed, Kuniyoshi Shimizu   +11 more
doaj   +1 more source

Identification and Distribution of Sterols, Bile Acids, and Acylcarnitines by LC–MS/MS in Humans, Mice, and Pigs—A Qualitative Analysis

Metabolites, 2022
Sterols, bile acids, and acylcarnitines are key players in human metabolism. Precise annotations of these metabolites with mass spectrometry analytics are challenging because of the presence of several isomers and stereoisomers, variability in ionization,
Ambrin Farizah Babu, Ville Mikael Koistinen, Soile Turunen, Gloria Solano-Aguilar, Joseph F. Urban, Iman Zarei, Kati Hanhineva   +6 more
doaj   +1 more source

Identification of unusual oxysterols biosynthesised in human pregnancy by charge-tagging and liquid chromatography - mass spectrometry

Frontiers in Endocrinology, 2022
The aim of this study was to identify oxysterols and any down-stream metabolites in placenta, umbilical cord blood plasma, maternal plasma and amniotic fluid to enhance our knowledge of the involvement of these molecules in pregnancy.
Alison L. Dickson, Eylan Yutuc, Catherine A. Thornton, Yuqin Wang, William J. Griffiths   +4 more
doaj   +1 more source

Structural Role of Plasma Membrane Sterols in Osmotic Stress Tolerance of Yeast Saccharomyces cerevisiae

Membranes, 2022
Yeast S. cerevisiae has been shown to suppress a sterol biosynthesis as a response to hyperosmotic stress. In the case of sodium stress, the failure to suppress biosynthesis leads to an increase in cytosolic sodium. The major yeast sterol, ergosterol, is
Svyatoslav S. Sokolov, Marina M. Popova, Peter Pohl, Andreas Horner, Sergey A. Akimov, Natalia A. Kireeva, Dmitry A. Knorre, Oleg V. Batishchev, Fedor F. Severin   +8 more
doaj   +1 more source

Antioxidant and Anti-Osteoporotic Activities of Aromatic Compounds and Sterols from Hericium erinaceum

Molecules, 2017
Hericium erinaceum, commonly called lion’s mane mushroom, is a traditional edible mushroom widely used in culinary applications and herbal medicines in East Asian countries. In this study, a new sterol, cerevisterol 6-cinnamate (6), was isolated from the
Wei Li, Sang Hyun Lee, Hae Dong Jang, Jin Yeul Ma, Young Ho Kim   +4 more
doaj   +1 more source

Endosperm sterol phenotype and germination in wheat [PDF]

, 1976
Free and conjugated sterols of endosperm, coats, scutellum, coleoptile and roots have been analysed at different germination stages in two wheat cultivars with different endosperm sterol phenotypes.
Carbonero Zalduegui, Pilar, García Olmedo, Francisco, Torres, V.   +2 more
core   +2 more sources