Results 21 to 30 of about 117,522 (314)

Green Microalgae Strain Improvement for the Production of Sterols and Squalene

Plants, 2021
Sterols and squalene are essential biomolecules required for the homeostasis of eukaryotic membrane permeability and fluidity. Both compounds have beneficial effects on human health. As the current sources of sterols and squalene are plant and shark oils,
Supakorn Potijun, Suparat Jaingam, Nuttha Sanevas, Srunya Vajrodaya, Anchalee Sirikhachornkit   +4 more
doaj   +1 more source

The Cerebrospinal Fluid Profile of Cholesterol Metabolites in Parkinson’s Disease and Their Association With Disease State and Clinical Features

Frontiers in Aging Neuroscience, 2021
Disordered cholesterol metabolism is linked to neurodegeneration. In this study we investigated the profile of cholesterol metabolites found in the cerebrospinal fluid (CSF) of Parkinson’s disease (PD) patients. When adjustments were made for confounding
William J. Griffiths, Jonas Abdel-Khalik, Sarah F. Moore, Ruwani S. Wijeyekoon, Peter J. Crick, Eylan Yutuc, Krista Farrell, David P. Breen, David P. Breen, David P. Breen, Caroline H. Williams-Gray, Spyridon Theofilopoulos, Ernest Arenas, Miles Trupp, Roger A. Barker, Roger A. Barker, Yuqin Wang   +16 more
doaj   +1 more source

Identification of twenty-three mutations in fission yeast Scap that constitutively activate SREBP*

Journal of Lipid Research, 2008
The endoplasmic reticulum membrane protein SREBP cleavage-activating protein (Scap) senses sterols and regulates activation of sterol-regulatory element binding proteins (SREBPs), membrane-bound transcription factors that control lipid homeostasis in ...
Adam L. Hughes, Emerson V. Stewart, Peter J. Espenshade   +2 more
doaj   +1 more source

The zinc cluster protein Sut1 contributes to filamentation in Saccharomyces cerevisiae [PDF]

, 2013
Copyright © 2013, American Society for Microbiology. All Rights ReservedSut1 is a transcriptional regulator of the Zn(II)(2)Cys(6) family in the budding yeast Saccharomyces cerevisiae.
Höfken, T, Cui, M, Unden, H, Foster, HA, Naveenathayalan, A, Schwanbeck, R   +5 more
core   +1 more source

Effects of genotype and sowing date on phytostanol-phytosterol content and agronomic traits in wheat under organic agriculture [PDF]

, 2009
Cereals are an important source of sterols and stanols in the human diet. The present study underlines the effect of genotype and weather conditions in bread wheat, on total sterol and stanol content (TSS), agronomic traits, proteins and ash content ...
Merah, Othmane,, Cerny, Muriel, Bouniols, Andrée, Mouloungui, Zephirin,, Alignan, Marion,, Alignan, Marion, Mouloungui, Zéphirin, Cerny, Muriel,, Merah, Othmane, Roche, Jane   +9 more
core   +1 more source

Sterols from Thai Marine Sponge Petrosia (Strongylophora) sp. and Their Cytotoxicity

Marine Drugs, 2017
Eight new sterols (1–5 and 11–13), together with eight known compounds (6–10 and 14–16) were isolated from marine sponge Petrosia sp. The structures of these compounds were elucidated on the basis of extensive spectroscopic analysis.
Phanruethai Pailee, Chulabhorn Mahidol, Somsak Ruchirawat, Vilailak Prachyawarakorn   +3 more
doaj   +1 more source

Characterization of the sterol 14α-demethylases of Fusarium graminearum identifies a novel genus-specific CYP51 function [PDF]

, 2013
CYP51 encodes the cytochrome P450 sterol 14-demethylase, an enzyme essential for sterol biosynthesis and the target of azole fungicides. In Fusarium species, including pathogens of humans and plants, three CYP51 paralogues have been identified with one ...
Brewer, H. C., Bart A. Fraaije, Liu, X., Josie Parker, Urban, M., Hammond-Kosack, K. E., Josie E. Parker, Fraaije, B. A., Steven Kelly, Fan, J., Kelly, S. L., Steven L. Kelly, Kim E. Hammond‐Kosack, Martin Urban, Parker, J. E., Jieru Fan, Helen C. Brewer, Xili Liu, Hans J. Cools, Cools, H. J.   +19 more
core   +1 more source

Modulation of Lipid Transport and Adipose Tissue Deposition by Small Lipophilic Compounds

Frontiers in Cell and Developmental Biology, 2020
Small lipophilic molecules present in foods of plant origin have relevant biological activities at rather low concentrations. Evidence suggests that phytosterols, carotenoids, terpenoids, and tocopherols can interact with different metabolic pathways ...
José M. Castellano, Juan M. Espinosa, Javier S. Perona   +2 more
doaj   +1 more source

Sterol content analysis suggests altered eburicol 14 alpha-demethylase (CYP51) activity in isolates of Mycosphaerella graminicola adapted to azole fungicides [PDF]

, 2009
The recent decline in the effectiveness of some azole fungicides in controlling the wheat pathogen Mycosphaerella graminicola has been associated with mutations in the CYP51 gene encoding the azole target, the eburicol 14 alpha-demethylase (CYP51), an ...
Bean, T. P., Michael W. Shaw, Shaw, M. W., Bart A. Fraaije, Bean, T. P., Hawkins, N. D., Cools, H. J., Tim P. Bean, Jane L. Ward, Fraaije, B. A., Fraaije, B. A., Shaw, M. W., Hawkins, N. D., John A. Lucas, Ward, J. L., Lucas, J. A., Nathaniel D. Hawkins, Lucas, J. A., Hans J. Cools, Cools, H. J., Ward, J. L.   +20 more
core   +1 more source

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source