Genetically Encoded Sterol-Modification of a Synthetic Intrinsically Disordered Protein Drives Its Self-Assembly Into Diverse Morphologies. [PDF]
Kim SY +9 more
europepmc +1 more source
ABSTRACT This systematic review and meta‐analysis of randomized controlled trials (RCTs) was conducted to assess the effect of nutraceuticals containing Citrus bergamia on the management of obesity in adults by assessing measures related to obesity. We searched the following databases until October 2024: PubMed, Web of Science, Scopus, and the Cochrane
Carmelo Pujia +8 more
wiley +1 more source
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +2 more sources
Site-Specific Abiraterone Protein-Drug Conjugates via Hedgehog Autoprocessing. [PDF]
Gulzar A +8 more
europepmc +1 more source
Abstract This study investigated the combined effects of alcohol and sugar, termed sweetened alcohol consumption (SAC), and tannic acid (TA) intervention on hepatic health in adolescent rats. Sixty‐four male and female 42‐day‐old Sprague–Dawley rats were assigned to control, TA (50 mg/kg), SAC (10% ethanol +20% fructose), or SAC+TA groups and treated ...
Toluwase E. Olanipekun +4 more
wiley +1 more source
Antifungal efficacy of linoleic-acid-rich Cucurbita pepo L. seed oil revealed by GC-MS profiling of lipids and bioactive markers, ergosterol depletion, and network pharmacology. [PDF]
Mohamed ET.
europepmc +1 more source
Four isostructural complexes (C1–C4) derived from 2‐(tert‐butoxy)‐6‐(1H‐imidazol‐1‐yl)pyridine with axial halides exhibit octahedral trans M(L)4X2 geometries, confirmed by X‐ray diffraction. They feature a discrete 1,6M7−1 topology, identified using ToposPro analysis.
David Ezenarro‐Salcedo +10 more
wiley +1 more source
Maternal cariprazine exposure effects on lactating offspring sterol biosynthesis. [PDF]
Anderson AC +3 more
europepmc +1 more source
Evolutionary diversity of sphingolipid metabolism proteins in fungi. [PDF]
Płecha M +8 more
europepmc +1 more source
Targeting cholesterol-driven immunometabolism in cancer: from molecular circuits to clinical translation. [PDF]
Ma Q, Chen B, Li T, Lu Y, Li X.
europepmc +1 more source

